| Peripheral cannabinoid receptor, CB2, regulates bone mass O Ofek, M Karsak, N Leclerc, M Fogel, B Frenkel, K Wright, J Tam, ... Proceedings of the National Academy of Sciences 103 (3), 696-701, 2006 | 581 | 2006 |
| Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity J Tam, VK Vemuri, J Liu, S Bátkai, B Mukhopadhyay, G Godlewski, ... The Journal of clinical investigation 120 (8), 2953-2966, 2010 | 477 | 2010 |
| Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes T Jourdan, G Godlewski, R Cinar, A Bertola, G Szanda, J Liu, J Tam, ... Nature medicine 19 (9), 1132-1140, 2013 | 339 | 2013 |
| Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance J Tam, R Cinar, J Liu, G Godlewski, D Wesley, T Jourdan, G Szanda, ... Cell metabolism 16 (2), 167-179, 2012 | 305 | 2012 |
| Depression induces bone loss through stimulation of the sympathetic nervous system R Yirmiya, I Goshen, A Bajayo, T Kreisel, S Feldman, J Tam, V Trembovler, ... Proceedings of the National Academy of Sciences 103 (45), 16876-16881, 2006 | 237 | 2006 |
| Endocannabinoids in liver disease J Tam, J Liu, B Mukhopadhyay, R Cinar, G Godlewski, G Kunos Hepatology 53 (1), 346-355, 2011 | 207 | 2011 |
| The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling J Tam, V Trembovler, V Di Marzo, S Petrosino, G Leo, A Alexandrovich, ... The FASEB journal 22 (1), 285-294, 2008 | 195 | 2008 |
| Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice J Liu, L Zhou, K Xiong, G Godlewski, B Mukhopadhyay, J Tam, S Yin, ... Gastroenterology 142 (5), 1218-1228. e1, 2012 | 172 | 2012 |
| Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling J Tam, O Ofek, E Fride, C Ledent, Y Gabet, R Müller, A Zimmer, K Mackie, ... Molecular pharmacology 70 (3), 786-792, 2006 | 165 | 2006 |
| Hepatic cannabinoid‐1 receptors mediate diet‐induced insulin resistance by increasing de novo synthesis of long‐chain ceramides R Cinar, G Godlewski, J Liu, J Tam, T Jourdan, B Mukhopadhyay, ... Hepatology 59 (1), 143-153, 2014 | 139 | 2014 |
| Endocannabinoids and the regulation of bone metabolism I Bab, O Ofek, J Tam, J Rehnelt, A Zimmer Journal of neuroendocrinology 20, 69-74, 2008 | 138 | 2008 |
| The case for peripheral CB1 receptor blockade in the treatment of visceral obesity and its cardiometabolic complications G Kunos, J Tam British journal of pharmacology 163 (7), 1423-1431, 2011 | 117 | 2011 |
| Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet S Srivastava, Y Kashiwaya, MT King, U Baxa, J Tam, G Niu, X Chen, ... The FASEB Journal 26 (6), 2351-2362, 2012 | 110 | 2012 |
| Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy T Jourdan, G Szanda, AZ Rosenberg, J Tam, BJ Earley, G Godlewski, ... Proceedings of the National Academy of Sciences 111 (50), E5420-E5428, 2014 | 95 | 2014 |
| Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects G Godlewski, SO Alapafuja, S Bátkai, SP Nikas, R Cinar, L Offertáler, ... Chemistry & biology 17 (11), 1256-1266, 2010 | 92 | 2010 |
| miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression G Hanin, N Yayon, Y Tzur, R Haviv, ER Bennett, S Udi, ... Gut 67 (6), 1124-1134, 2018 | 85 | 2018 |
| Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver B Mukhopadhyay, R Cinar, S Yin, J Liu, J Tam, G Godlewski, ... Proceedings of the National Academy of Sciences 108 (15), 6323-6328, 2011 | 85 | 2011 |
| Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer S Sen, I Talukdar, Y Liu, J Tam, S Reddy, NJG Webster Journal of Biological Chemistry 285 (33), 25426-25437, 2010 | 77 | 2010 |
| Oleoyl serine, an endogenous N-acyl amide, modulates bone remodeling and mass R Smoum, A Bar, B Tan, G Milman, M Attar-Namdar, O Ofek, JM Stuart, ... Proceedings of the National Academy of Sciences 107 (41), 17710-17715, 2010 | 72 | 2010 |
| Lower circulating endocannabinoid levels in children with autism spectrum disorder A Aran, M Eylon, M Harel, L Polianski, A Nemirovski, S Tepper, ... Molecular autism 10 (1), 1-11, 2019 | 69 | 2019 |
George KunosScientific Director, NIAAA/NIHVerified email at nih.gov
