Radiosynthesis and bioimaging of the tuberculosis chemotherapeutics isoniazid, rifampicin and pyrazinamide in baboons L Liu, Y Xu, C Shea, JS Fowler, JM Hooker, PJ Tonge Journal of medicinal chemistry 53 (7), 2882-2891, 2010 | 87 | 2010 |
Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor J Schiebel, A Chang, S Shah, Y Lu, L Liu, P Pan, MW Hirschbeck, ... Journal of Biological Chemistry 289 (23), 15987-16005, 2014 | 72 | 2014 |
Noninvasive determination of 2-[18F]-fluoroisonicotinic acid hydrazide pharmacokinetics by positron emission tomography in Mycobacterium tuberculosis-infected mice EA Weinstein, L Liu, AA Ordonez, H Wang, JM Hooker, PJ Tonge, SK Jain Antimicrobial agents and chemotherapy 56 (12), 6284-6290, 2012 | 67 | 2012 |
Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase H Wang, L Liu, Y Lu, P Pan, JM Hooker, JS Fowler, PJ Tonge Bioorganic & medicinal chemistry letters 25 (21), 4782-4786, 2015 | 11 | 2015 |
Radiosynthesis and biological evaluation of a novel enoyl-ACP reductase inhibitor for Staphylococcus aureus H Wang, Y Lu, L Liu, SW Kim, JM Hooker, JS Fowler, PJ Tonge European journal of medicinal chemistry 88, 66-73, 2014 | 9 | 2014 |
Radiolabelling of novel enoyl-ACP reductase inhibitors for non-invasive imaging of Staphylococcus aureus infection in mice using PET H Wang, Y Lu, L Liu, D Alexoff, SW Kim, J Fowler, P Tonge Journal of Nuclear Medicine 54 (supplement 2), 1094-1094, 2013 | | 2013 |
Noninvasive Determination of 2-[18F]-Fluoroisonicotinic Acid Hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis-Infected Mice EA Weinstein, L Liu, AA Ordonez, H Wang, JM Hooker, PJ Tonge, SK Jain Antimicrobial agents and chemotherapy 57 (1), 678, 2013 | | 2013 |
Imaging the distribution of Carbon-11 labeled rifampicin, isoniazid and pyrazinamide in baboons using PET L Liu, Y Xu, C Shea, J Fowler, J Hooker, P Tonge Journal of Nuclear Medicine 52 (supplement 1), 1517-1517, 2011 | | 2011 |
The Use of Short lived Isotopes for Exploring Drug Binding Partners of Isoniazid in Mycobacterium Tuberculosis J Borgaro, L Liu, J Hooker, P Tonge The FASEB Journal 24 (1 Supplement), 681.3-681.3, 2010 | | 2010 |
Slow onset inhibitors of bacterial fatty acid biosynthesis: Residence time, in vivo activity and in vivo imaging PJ Tonge, C am Ende, S Knudson, S Luckner, BG Reddy, K England, ... The FASEB Journal 24 (1 Supplement), 71.3-71.3, 2010 | | 2010 |
Imaging the Distribution of Carbon-11 Labeled Rifampicin, Isoniazid and Pyrazinamide in Baboons using PET L Liu, JM Hooker, JS Fowler, PJ Tonge The FASEB Journal 24 (1 Supplement), 907.7-907.7, 2010 | | 2010 |