Mechanical regulation of glycolysis via cytoskeleton architecture JS Park, CJ Burckhardt, R Lazcano, LM Solis, T Isogai, L Li, CS Chen, ... Nature 578 (7796), 621-626, 2020 | 451 | 2020 |
Initiation of lamellipodia and ruffles involves cooperation between mDia1 and the Arp2/3 complex T Isogai, R van der Kammen, D Leyton-Puig, KM Kedziora, K Jalink, ... Journal of cell science 128 (20), 3796-3810, 2015 | 114 | 2015 |
Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors D Leyton-Puig, T Isogai, E Argenzio, B Van Den Broek, J Klarenbeek, ... Nature communications 8 (1), 16068, 2017 | 109 | 2017 |
SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton T Isogai, R Van Der Kammen, M Innocenti Scientific reports 5 (1), 9802, 2015 | 92 | 2015 |
Robust and automated detection of subcellular morphological motifs in 3D microscopy images MK Driscoll, ES Welf, AR Jamieson, KM Dean, T Isogai, R Fiolka, ... Nature methods 16 (10), 1037-1044, 2019 | 86 | 2019 |
Insights into the molecular evolution of the PDZ/LIM family and identification of a novel conserved protein motif AJW Te Velthuis, T Isogai, L Gerrits, CP Bagowski PloS one 2 (2), e189, 2007 | 84 | 2007 |
Actin-membrane release initiates cell protrusions ES Welf, CE Miles, J Huh, E Sapoznik, J Chi, MK Driscoll, T Isogai, J Noh, ... Developmental cell 55 (6), 723-736. e8, 2020 | 72 | 2020 |
PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins D Leyton-Puig, KM Kedziora, T Isogai, B van den Broek, K Jalink, ... Biology open 5 (7), 1001-1009, 2016 | 66 | 2016 |
Enhanced dendritic actin network formation in extended lamellipodia drives proliferation in growth-challenged Rac1P29S melanoma cells AS Mohan, KM Dean, T Isogai, SY Kasitinon, VS Murali, P Roudot, ... Developmental cell 49 (3), 444-460. e9, 2019 | 43 | 2019 |
New nuclear and perinuclear functions of formins T Isogai, M Innocenti Biochemical Society Transactions 44 (6), 1701-1708, 2016 | 29 | 2016 |
Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA–mDia2 signaling and filopodium formation E Argenzio, J Klarenbeek, KM Kedziora, L Nahidiazar, T Isogai, ... Journal of Biological Chemistry 293 (50), 19161-19176, 2018 | 25 | 2018 |
Proteomic analyses uncover a new function and mode of action for mouse homolog of Diaphanous 2 (mDia2)*[S] T Isogai, R Van Der Kammen, SS Goerdayal, AJR Heck, AFM Altelaar, ... Molecular & Cellular Proteomics 14 (4), 1064-1078, 2015 | 22 | 2015 |
Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation J Noh, T Isogai, J Chi, K Bhatt, G Danuser Cell systems 13 (6), 471-487. e8, 2022 | 19* | 2022 |
Invadosomes-shaping actin networks to follow mechanical cues K Kedziora, T Isogai, K Jalink, M Innocenti Frontiers in bioscience 21 (6), 1092-1117, 2016 | 18 | 2016 |
Discovery of functional interactions among actin regulators by analysis of image fluctuations in an unperturbed motile cell system T Isogai, G Danuser Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 17 | 2018 |
Cell forces meet cell metabolism T Isogai, JS Park, G Danuser Nature cell biology 19 (6), 591-593, 2017 | 17 | 2017 |
u-track 3D: measuring and interrogating dense particle dynamics in three dimensions P Roudot, WR Legant, Q Zou, KM Dean, T Isogai, ES Welf, AF David, ... BioRxiv, 2020.11. 30.404814, 2020 | 15 | 2020 |
u-track3D: Measuring, navigating, and validating dense particle trajectories in three dimensions P Roudot, WR Legant, Q Zou, KM Dean, T Isogai, ES Welf, AF David, ... Cell Reports Methods 3 (12), 2023 | 13 | 2023 |
Quantitative proteomics illuminates a functional interaction between mDia2 and the proteasome T Isogai, R Van Der Kammen, OB Bleijerveld, SS Goerdayal, E Argenzio, ... Journal of proteome research 15 (12), 4624-4637, 2016 | 13 | 2016 |
Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D T Isogai, KM Dean, P Roudot, Q Shao, JD Cillay, ES Welf, MK Driscoll, ... bioRxiv, 756718, 2019 | 12 | 2019 |