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Stefanie Saenger
Stefanie Saenger
Principal Associate, Neuroscience and Rare Diseases, Exploratory Neurobiology - Target Engagement
Verified email at roche.com
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Cited by
Cited by
Year
Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and mouse behaviour
O Hernández-Hernández, C Guiraud-Dogan, G Sicot, A Huguet, S Luilier, ...
Brain 136 (3), 957-970, 2013
862013
Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK1 receptor antagonist
TM Ballard, S Sänger, GA Higgins
European journal of pharmacology 412 (3), 255-264, 2001
702001
Separation of fast from slow anabolism by site-specific PEGylation of insulin-like growth factor I (IGF-I)
F Metzger, W Sajid, S Saenger, C Staudenmaier, C van der Poel, ...
Journal of Biological Chemistry 286 (22), 19501-19510, 2011
502011
Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function
MR Pitcher, CS Ward, EM Arvide, CA Chapleau, L Pozzo-Miller, ...
Human Molecular Genetics 22 (13), 2626-2633, 2013
472013
Polyethylene glycol-coupled IGF1 delays motor function defects in a mouse model of spinal muscular atrophy with respiratory distress type 1
F Krieger, N Elflein, S Saenger, E Wirthgen, K Rak, S Frantz, A Hoeflich, ...
Brain 137 (5), 1374-1393, 2014
412014
PEGylation enhances the therapeutic potential for insulin-like growth factor I in central nervous system disorders
S Saenger, C Goeldner, JR Frey, L Ozmen, S Ostrowitzki, W Spooren, ...
Growth Hormone & IGF Research 21 (5), 292-303, 2011
352011
Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity
S Saenger, B Holtmann, MR Nilges, S Schroeder, A Hoeflich, H Kletzl, ...
Amyotrophic lateral sclerosis 13 (5), 418-429, 2012
322012
Impaired myogenic development, differentiation and function in hESC-derived SMA myoblasts and myotubes
N Hellbach, S Peterson, D Haehnke, A Shankar, S LaBarge, C Pivaroff, ...
PLoS One 13 (10), e0205589, 2018
252018
PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia
K Parker, A Berretta, S Saenger, M Sivaramakrishnan, SA Shirley, ...
Scientific Reports 7 (1), 241, 2017
192017
Intramuscular administration of PEGylated IGF-I improves skeletal muscle regeneration after myotoxic injury
KJB Martins, SM Gehrig, T Naim, S Saenger, D Baum, F Metzger, ...
Growth Hormone & IGF Research 23 (4), 128-133, 2013
152013
Phenotype analysis of male transgenic mice overexpressing mutant IGFBP-2 lacking the Cardin–Weintraub sequence motif: Reduced expression of synaptic markers and myelin basic …
N Schindler, J Mayer, S Saenger, U Gimsa, C Walz, J Brenmoehl, D Ohde, ...
Growth Hormone & IGF Research 33, 1-8, 2017
132017
Assessment of systemic administration of PEGylated IGF-1 in a mouse model of traumatic brain injury
DM Sama, SW Carlson, B Joseph, S Saenger, F Metzger, KE Saatman
Restorative neurology and neuroscience 36 (4), 559-569, 2018
112018
PEGylation of lysine residues reduces the pro-migratory activity of IGF-I
M Sivaramakrishnan, AS Kashyap, B Amrein, S Saenger, S Meier, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (10), 4734-4742, 2013
112013
Skeletal muscle dysfunction and mitochondrial deficits in spinal muscular atrophy (SMA)
N Hellbach, KD McCarthy, S Saenger, S Peterson, U Schmidt, S Paushkin, ...
Neuromuscular Disorders 1 (27), S30, 2017
12017
PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia
A Clarkson, A Berretta, F Metzger, K Parker, S Saenger, SA Shirley, ...
Nature Publishing Group, 2017
2017
OR2-3: The Cardin-Weintraub Motif present in IGFBP-2 is required for growth and function of the mouse brain
N Schindler, J Mayer, T Kirschstein, S Saenger, U Gimsa, J Brenmoehl, ...
Growth Hormone & IGF Research, S8, 2014
2014
P02-33 Intramuscular administration of PEGylated IGF-I accelerates skeletal muscle regeneration after myotoxic injury
F Metzger, KJ Martins, SM Gehrig, T Naim, S Saenger, D Baum, GS Lynch
Growth Hormone & IGF Research, S54-S55, 2012
2012
P78 Elimination of acute drug side effects without loss of efficacy by site-specific PEGylation of insulin-like growth factor I
F Metzger, C Staudenmaier, S Saenger, A Schuler, W Sajid, F Hesse, ...
Growth Hormone & IGF Research, S67, 2010
2010
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