| Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling N Kayagaki, IB Stowe, BL Lee, K O’Rourke, K Anderson, S Warming, ... Nature 526 (7575), 666-671, 2015 | 3069 | 2015 |
| Differential activation of transcription factors induced by Ca2+ response amplitude and duration RE Dolmetsch, RS Lewis, CC Goodnow, JI Healy Nature 386 (6627), 855-858, 1997 | 2394 | 1997 |
| Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice CC Goodnow, J Crosbie, S Adelstein, TB Lavoie, SJ Smith-Gill, RA Brink, ... Nature 334 (6184), 676-682, 1988 | 1976 | 1988 |
| C3d of complement as a molecular adjuvant: bridging innate and acquired immunity PW Dempsey, MED Allison, S Akkaraju, CC Goodnow, DT Fearon Science 271 (5247), 348-350, 1996 | 1564 | 1996 |
| A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity CG Vinuesa, MC Cook, C Angelucci, V Athanasopoulos, L Rui, KM Hill, ... Nature 435 (7041), 452-458, 2005 | 994 | 2005 |
| Aire regulates negative selection of organ-specific T cells A Liston, S Lesage, J Wilson, L Peltonen, CC Goodnow Nature immunology 4 (4), 350-354, 2003 | 987 | 2003 |
| Cellular and genetic mechanisms of self tolerance and autoimmunity CC Goodnow, J Sprent, BF de St Groth, CG Vinuesa Nature 435 (7042), 590-597, 2005 | 940 | 2005 |
| Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens SB Hartley, J Crosbie, R Brink, AB Kantor, A Basten, CC Goodnow Nature 353 (6346), 765-769, 1991 | 918 | 1991 |
| Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis CK Heazlewood, MC Cook, R Eri, GR Price, SB Tauro, D Taupin, ... PLoS medicine 5 (3), e54, 2008 | 820 | 2008 |
| Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus N Simpson, PA Gatenby, A Wilson, S Malik, DA Fulcher, SG Tangye, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2010 | 818 | 2010 |
| Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death SB Hartley, MP Cooke, DA Fulcher, AW Harris, S Cory, A Basten, ... Cell 72 (3), 325-335, 1993 | 703 | 1993 |
| Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire JG Cyster, SB Hartley, CC Goodnow Nature 371 (6496), 389-395, 1994 | 695 | 1994 |
| Two levels of protection for the B cell genome during somatic hypermutation M Liu, JL Duke, DJ Richter, CG Vinuesa, CC Goodnow, SH Kleinstein, ... Nature 451 (7180), 841-845, 2008 | 688 | 2008 |
| Induction of self-tolerance in mature peripheral B lymphocytes CC Goodnow, J Crosbie, H Jorgensen, RA Brink, A Basten Nature 342 (6248), 385-391, 1989 | 679 | 1989 |
| DNA repair is limiting for haematopoietic stem cells during ageing A Nijnik, L Woodbine, C Marchetti, S Dawson, T Lambe, C Liu, ... Nature 447 (7145), 686-690, 2007 | 603 | 2007 |
| CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells JC Rathmell, MP Cooke, WY Ho, J Grein, SE Townsend, MM Davis, ... Nature 376 (6536), 181-184, 1995 | 599 | 1995 |
| Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. CC Goodnow Proceedings of the National Academy of Sciences 93 (6), 2264-2271, 1996 | 584 | 1996 |
| Control systems and decision making for antibody production CC Goodnow, CG Vinuesa, KL Randall, F Mackay, R Brink Nature immunology 11 (8), 681-688, 2010 | 515 | 2010 |
| Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells DHD Gray, N Seach, T Ueno, MK Milton, A Liston, AM Lew, CC Goodnow, ... Blood 108 (12), 3777-3785, 2006 | 508 | 2006 |
| Expansion or elimination of B cells in vivo: dual roles for CD40-and Fas (CD95)-ligands modulated by the B cell antigen receptor JC Rathmell, SE Townsend, JC Xu, RA Flavell, CC Goodnow Cell 87 (2), 319-329, 1996 | 504 | 1996 |
