Noel Filipe de Miranda
Noel Filipe de Miranda
Principal Investigator at Leiden University Medical Center
Verified email at
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Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data
F Finotello, C Mayer, C Plattner, G Laschober, D Rieder, H Hackl, ...
Genome medicine 11, 1-20, 2019
Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors
T Duhen, R Duhen, R Montler, J Moses, T Moudgil, NF De Miranda, ...
Nature communications 9 (1), 2724, 2018
Neoantigen landscape dynamics during human melanoma–T cell interactions
EME Verdegaal, NFCC De Miranda, M Visser, T Harryvan, ...
Nature 536 (7614), 91-95, 2016
Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas
K Georgiou, L Chen, M Berglund, W Ren, NFCC de Miranda, S Lisboa, ...
Blood 127 (24), 3026-3034, 2016
Cancer immunotherapy: broadening the scope of targetable tumours
J van den Bulk, EME Verdegaal, NFCC de Miranda
Open biology 8 (6), 180037, 2018
The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers
LL Kodach, E Wiercinska, NFCC De Miranda, SA Bleuming, AR Musler, ...
Gastroenterology 134 (5), 1332-1341. e3, 2008
Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I–II colon cancer patients
WE Mesker, GJ Liefers, J Junggeburt, GW van Pelt, P Alberici, ...
Analytical Cellular Pathology 31 (3), 169-178, 2009
Mutational signature analysis reveals NTHL1 deficiency to cause a multi-tumor phenotype
JE Grolleman, RM De Voer, FA Elsayed, M Nielsen, RDA Weren, C Palles, ...
Cancer cell 35 (2), 256-266. e5, 2019
Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations
C Wu, NFCC de Miranda, L Chen, AM Wasik, L Mansouri, W Jurczak, ...
Oncotarget 7 (25), 38180, 2016
A 40-marker panel for high dimensional characterization of cancer immune microenvironments by imaging mass cytometry
ME Ijsselsteijn, R van der Breggen, A Farina Sarasqueta, F Koning, ...
Frontiers in immunology 10, 2534, 2019
Memory CD4+ T cells are generated in the human fetal intestine
N Li, V van Unen, T Abdelaal, N Guo, SA Kasatskaya, K Ladell, ...
Nature immunology 20 (3), 301-312, 2019
Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients
NFCC de Miranda, K Georgiou, L Chen, C Wu, Z Gao, A Zaravinos, ...
Blood 124 (16), 2544-2553, 2014
Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment
YM Schrage, IH Briaire-de Bruijn, NFCC de Miranda, J van Oosterwijk, ...
Cancer Research 69 (15), 6216-6222, 2009
High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity
NL De Vries, V Van Unen, ME Ijsselsteijn, T Abdelaal, R Van Der Breggen, ...
Gut 69 (4), 691-703, 2020
HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression
JWF Dierssen, NFCC de Miranda, S Ferrone, M van Puijenbroek, ...
BMC cancer 7, 1-11, 2007
Analysis of PD-L1, T-cell infiltrate and HLA expression in chondrosarcoma indicates potential for response to immunotherapy specifically in the dedifferentiated subtype
M Kostine, AHG Cleven, NFCC de Miranda, A Italiano, AM Cleton-Jansen, ...
Modern Pathology 29 (9), 1028-1037, 2016
γδ T cells are effectors of immunotherapy in cancers with HLA class I defects
NL de Vries, J van de Haar, V Veninga, M Chalabi, ME Ijsselsteijn, ...
Nature 613 (7945), 743-750, 2023
Iron loading is a prominent feature of activated microglia in Alzheimer’s disease patients
B Kenkhuis, A Somarakis, L de Haan, O Dzyubachyk, ME IJsselsteijn, ...
Acta neuropathologica communications 9, 1-15, 2021
DNA repair genes are selectively mutated in diffuse large B cell lymphomas
NFCC de Miranda, R Peng, K Georgiou, C Wu, EF Sörqvist, M Berglund, ...
Journal of Experimental Medicine 210 (9), 1729-1742, 2013
DNA repair: the link between primary immunodeficiency and cancer
NFCC de Miranda, A Björkman, Q Pan‐Hammarström
Annals of the New York Academy of Sciences 1246 (1), 50-63, 2011
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