| Atomic Structure of Acetyicholinesterase from JL Sussman, M Harel, F Frolow, C Oefner, A Goldman, L Toker, I Silman Science 253 (5022), 872-879, 1991 | 3100 | 1991 |
| The α/β hydrolase fold DL Ollis, E Cheah, M Cygler, B Dijkstra, F Frolow, SM Franken, M Harel, ... Protein Engineering, Design and Selection 5 (3), 197-211, 1992 | 2463 | 1992 |
| Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase M Harel, I Schalk, L Ehret-Sabatier, F Bouet, M Goeldner, C Hirth, ... Proceedings of the National Academy of Sciences 90 (19), 9031-9035, 1993 | 1030 | 1993 |
| FoldIndex©: a simple tool to predict whether a given protein sequence is intrinsically unfolded J Prilusky, CE Felder, T Zeev-Ben-Mordehai, EH Rydberg, O Man, ... Bioinformatics 21 (16), 3435-3438, 2005 | 1024 | 2005 |
| Three-dimensional tertiary structure of yeast phenylalanine transfer RNA SH Kim, FL Suddath, GJ Quigley, A McPherson, JL Sussman, AHJ Wang, ... Science 185 (4149), 435-440, 1974 | 1009 | 1974 |
| Function and structure of inherently disordered proteins AK Dunker, I Silman, VN Uversky, JL Sussman Current opinion in structural biology 18 (6), 756-764, 2008 | 937 | 2008 |
| Protein production and purification S Gräslund, P Nordlund, J Weigelt, BM Hallberg, J Bray, O Gileadi, ... Nature methods 5 (2), 135, 2008 | 817 | 2008 |
| Three-dimensional structures of avidin and the avidin-biotin complex O Livnah, EA Bayer, M Wilchek, JL Sussman Proceedings of the National Academy of Sciences 90 (11), 5076-5080, 1993 | 783 | 1993 |
| Structure of acetylcholinesterase complexed with E2020 (Aricept®): implications for the design of new anti-Alzheimer drugs G Kryger, I Silman, JL Sussman Structure 7 (3), 297-307, 1999 | 751 | 1999 |
| Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes M Harel, A Aharoni, L Gaidukov, B Brumshtein, O Khersonsky, R Meged, ... Nature structural & molecular biology 11 (5), 412-419, 2004 | 717 | 2004 |
| The pitch of chromatin DNA is reflected in its nucleotide sequence EN Trifonov, JL Sussman Proceedings of the National Academy of Sciences 77 (7), 3816-3820, 1980 | 685 | 1980 |
| Relationship between sequence conservation and three‐dimensional structure in a large family of esterases, lipases, and related proteins M Cygler, JD Schrag, JL Sussman, M Harel, I Silman, MK Gentry, ... Protein Science 2 (3), 366-382, 1993 | 681 | 1993 |
| Acetylcholinesterase: from 3D structure to function H Dvir, I Silman, M Harel, TL Rosenberry, JL Sussman Chemico-biological interactions 187 (1-3), 10-22, 2010 | 570 | 2010 |
| Specific chemical and structural damage to proteins produced by synchrotron radiation M Weik, RBG Ravelli, G Kryger, S McSweeney, ML Raves, M Harel, ... Proceedings of the National Academy of Sciences 97 (2), 623-628, 2000 | 555 | 2000 |
| Protein Data Bank (PDB): database of three-dimensional structural information of biological macromolecules JL Sussman, D Lin, J Jiang, NO Manning, J Prilusky, O Ritter, EE Abola Acta Crystallographica Section D: Biological Crystallography 54 (6), 1078-1084, 1998 | 551 | 1998 |
| Acetylcholinesterase:‘classical’and ‘non-classical’functions and pharmacology I Silman, JL Sussman Current opinion in pharmacology 5 (3), 293-302, 2005 | 542 | 2005 |
| Structure of acetylcholinesterase complexed with the nootropic alkaloid,(–)-huperzine A ML Raves, M Harel, YP Pang, I Silman, AP Kozikowski, JL Sussman Nature structural biology 4 (1), 57-63, 1997 | 510 | 1997 |
| Crystal structure of yeast phenylalanine transfer RNA: I. Crystallographic refinement JL Sussman, SR Holbrook, RW Warrant, GM Church, SH Kim Journal of molecular biology 123 (4), 607-630, 1978 | 414 | 1978 |
| The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase M Harel, DM Quinn, HK Nair, I Silman, JL Sussman Journal of the American Chemical Society 118 (10), 2340-2346, 1996 | 412 | 1996 |
| Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system Y Shaaltiel, D Bartfeld, S Hashmueli, G Baum, E Brill‐Almon, G Galili, ... Plant biotechnology journal 5 (5), 579-590, 2007 | 390 | 2007 |
Felix FrolowProfessor of Structural Biology and BiotechnologyVerified email at post.tau.ac.il
