Bruno Pagano
Bruno Pagano
Department of Pharmacy, University of Naples Federico II
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Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4
L Martino, A Virno, B Pagano, A Virgilio, S Di Micco, A Galeone, ...
Journal of the American Chemical Society 129 (51), 16048-16056, 2007
Stability and binding properties of a modified thrombin binding aptamer
B Pagano, L Martino, A Randazzo, C Giancola
Biophysical Journal 94 (2), 562-569, 2008
Structural revision of clusianone and 7-epi-clusianone and anti-HIV activity of polyisoprenylated benzophenones
AL Piccinelli, O Cuesta-Rubio, MB Chica, N Mahmood, B Pagano, ...
Tetrahedron 61 (34), 8206-8211, 2005
Shedding light on the interaction between TMPyP4 and human telomeric quadruplexes
L Martino, B Pagano, I Fotticchia, S Neidle, C Giancola
The Journal of Physical Chemistry B 113 (44), 14779-14786, 2009
The G‐Triplex DNA
V Limongelli, S De Tito, L Cerofolini, M Fragai, B Pagano, R Trotta, ...
Angewandte Chemie 125 (8), 2325-2329, 2013
Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle
S Cosconati, L Marinelli, R Trotta, A Virno, S De Tito, R Romagnoli, ...
Journal of the American Chemical Society 132 (18), 6425-6433, 2010
Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes
B Pagano, CA Mattia, C Giancola
International Journal of Molecular Sciences 10 (7), 2935-2957, 2009
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations
F Moraca, J Amato, F Ortuso, A Artese, B Pagano, E Novellino, S Alcaro, ...
Proceedings of the National Academy of Sciences 114 (11), E2136-E2145, 2017
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death
S Cosconati, A Rizzo, R Trotta, B Pagano, S Iachettini, S De Tito, I Lauri, ...
Journal of Medicinal Chemistry 55 (22), 9785-9792, 2012
Targeting DNA quadruplexes with distamycin A and its derivatives: an ITC and NMR study
B Pagano, A Virno, CA Mattia, L Mayol, A Randazzo, C Giancola
Biochimie 90 (8), 1224-1232, 2008
Thermodynamics and Kinetics of PNA− DNA Quadruplex-Forming Chimeras
L Petraccone, B Pagano, V Esposito, A Randazzo, G Piccialli, G Barone, ...
Journal of the American Chemical Society 127 (46), 16215-16223, 2005
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis
E Salvati, P Zizza, A Rizzo, S Iachettini, C Cingolani, C D’Angelo, M Porru, ...
Nucleic Acids Research 42 (5), 2945-2957, 2014
State-of-the-Art Methodologies for the Discovery and Characterization of DNA G-Quadruplex Binders.
B Pagano, S Cosconati, V Gabelica, L Petraccone, S De Tito, L Marinelli, ...
Current Pharmaceutical Design 18 (14), 1880-1899, 2012
Energetics of quadruplex-drug recognition in anticancer therapy
B Pagano, C Giancola
Current Cancer Drug Targets 7 (6), 520-540, 2007
Toward the development of specific G-quadruplex binders: Synthesis, biophysical, and biological studies of new hydrazone derivatives
J Amato, R Morigi, B Pagano, A Pagano, S Ohnmacht, A De Magis, ...
Journal of Medicinal Chemistry 59 (12), 5706-5720, 2016
Studying the effect of crowding and dehydration on DNA G-quadruplexes
L Petraccone, B Pagano, C Giancola
Methods 57 (1), 76-83, 2012
Exploring the Chemical Space of G-Quadruplex Binders: Discovery of a Novel Chemotype Targeting the Human Telomeric Sequence
FS Di Leva, P Zizza, C Cingolani, C D'Angelo, B Pagano, J Amato, ...
Journal of Medicinal Chemistry 56 (23), 9646–9654, 2013
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands
A Peduto, B Pagano, C Petronzi, A Massa, V Esposito, A Virgilio, ...
Bioorganic & Medicinal Chemistry 19 (21), 6419-6429, 2011
Targeting G-Quadruplex Structure in the Human c-Kit Promoter with Short PNA Sequences
J Amato, B Pagano, N Borbone, G Oliviero, V Gabelica, ED Pauw, ...
Bioconjugate Chemistry 22 (4), 654-663, 2011
Looking for efficient G‐quadruplex ligands: evidence for selective stabilizing properties and telomere damage by drug‐like molecules
B Pagano, J Amato, N Iaccarino, C Cingolani, P Zizza, A Biroccio, ...
ChemMedChem 10 (4), 640-649, 2015
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