Quantitative MALDI tandem mass spectrometric imaging of cocaine from brain tissue with a deuterated internal standard DA Pirman, RF Reich, A Kiss, RMA Heeren, RA Yost Analytical chemistry 85 (2), 1081-1089, 2013 | 183 | 2013 |
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer Nature 547, 109-113, 2017 | 179 | 2017 |
Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase AK Padyana, S Gross, L Jin, G Cianchetta, R Narayanaswamy, F Wang, ... Nature communications 10 (1), 97, 2019 | 103 | 2019 |
Quantitative tandem mass spectrometric imaging of endogenous acetyl-L-carnitine from piglet brain tissue using an internal standard DA Pirman, RA Yost Analytical chemistry 83 (22), 8575-8581, 2011 | 88 | 2011 |
Recurrent germline DLST mutations in individuals with multiple pheochromocytomas and paragangliomas L Remacha, D Pirman, CE Mahoney, J Coloma, B Calsina, ... The American Journal of Human Genetics 104 (4), 651-664, 2019 | 85 | 2019 |
Identifying tissue-specific signal variation in MALDI mass spectrometric imaging by use of an internal standard DA Pirman, A Kiss, RMA Heeren, RA Yost Analytical chemistry 85 (2), 1090-1096, 2013 | 84 | 2013 |
A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition CE Mahoney, D Pirman, V Chubukov, T Sleger, S Hayes, ZP Fan, ... Nature communications 10 (1), 96, 2019 | 70 | 2019 |
Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDH Cell Reports 17 (3), 876-890, 2016 | 67 | 2016 |
Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer SA Best, PM Gubser, S Sethumadhavan, A Kersbergen, YLN Abril, ... Cell Metabolism 34 (6), 874-887. e6, 2022 | 61 | 2022 |
Targeting hepatic glutaminase activity to ameliorate hyperglycemia RA Miller, Y Shi, W Lu, DA Pirman, A Jatkar, M Blatnik, H Wu, C Cárdenas, ... Nature medicine 24 (4), 518-524, 2018 | 61 | 2018 |
Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5) K Huard, J Brown, JC Jones, S Cabral, K Futatsugi, M Gorgoglione, ... Scientific reports 5 (1), 17391, 2015 | 61 | 2015 |
Changes in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometry DA Pirman, E Efuet, XP Ding, Y Pan, L Tan, SM Fischer, RN DuBois, ... PloS one 8 (4), e61379, 2013 | 43 | 2013 |
Preclinical toxicology profile of squalene epoxidase inhibitors R Nagaraja, A Olaharski, R Narayanaswamy, C Mahoney, D Pirman, ... Toxicology and Applied Pharmacology 401, 115103, 2020 | 16 | 2020 |
Quantitative profiling of tissue drug distribution by MS imaging D Pirman Bioanalysis 7 (20), 2649-2656, 2015 | 12 | 2015 |
Metabolic analysis reveals evidence for branched chain amino acid catabolism crosstalk and the potential for improved treatment of organic acidurias S McCalley, D Pirman, M Clasquin, K Johnson, S Jin, J Vockley Molecular genetics and metabolism 128 (1-2), 57-61, 2019 | 11 | 2019 |
Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase. Nat Commun 10: 97 AK Padyana, S Gross, L Jin, G Cianchetta, R Narayanaswamy, F Wang, ... | 11 | 2019 |
Phenotyping hepatocellular metabolism using uniformly labeled carbon-13 molecular probes and LC-HRMS stable isotope tracing JK Meissen, DA Pirman, M Wan, E Miller, A Jatkar, R Miller, RC Steenwyk, ... Analytical Biochemistry 508, 129-137, 2016 | 11 | 2016 |
Correction: Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer A Zabala-Letona, A Arruabarrena-Aristorena, N Martín-Martín, ... Nature 554 (7693), 554-554, 2018 | 8 | 2018 |
Plasma concentration and local anesthetic activity of procaine hydrochloride following subcutaneous administration to horses NL Kuchembuck, PT Colahan, KD Zientek, DA Pirman, K Wegner, ... American journal of veterinary research 68 (5), 495-500, 2007 | 8 | 2007 |
Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux SN Masud, M Chandrashekhar, M Aregger, G Tan, X Zhang, P Mero, ... Nature Chemical Biology 18 (12), 1370-1379, 2022 | 3 | 2022 |