| A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis L Fang, Q Zhu, M Neuenschwander, E Specker, A Wulf-Goldenberg, ... Cancer research 76 (4), 891-901, 2016 | 174 | 2016 |
| Wnt/β‐catenin signalling induces MLL to create epigenetic changes in salivary gland tumours P Wend, L Fang, Q Zhu, JH Schipper, C Loddenkemper, F Kosel, ... The EMBO journal 32 (14), 1977-1989, 2013 | 116 | 2013 |
| KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells X Qi, Y Li, Y Zhang, T Xu, B Lu, L Fang, J Gao, L Yu, D Zhu, B Yang, Q He, ... Acta Pharmacologica Sinica 40 (4), 546-555, 2019 | 101 | 2019 |
| A deep learning framework to predict binding preference of RNA constituents on protein surface JH Lam, Y Li, L Zhu, R Umarov, H Jiang, A Héliou, FK Sheong, T Liu, ... Nature communications 10 (1), 4941, 2019 | 84 | 2019 |
| Design, synthesis and evaluation of galanthamine derivatives as acetylcholinesterase inhibitors P Jia, R Sheng, J Zhang, L Fang, Q He, B Yang, Y Hu European Journal of Medicinal Chemistry 44 (2), 772-784, 2009 | 81 | 2009 |
| Combined Wnt/β-catenin, Met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome JD Holland, B Györffy, R Vogel, K Eckert, G Valenti, L Fang, P Lohneis, ... Cell reports 5 (5), 1214-1227, 2013 | 78 | 2013 |
| Q39, a novel synthetic Quinoxaline 1, 4-Di-N-oxide compound with anti-cancer activity in hypoxia Q Weng, D Wang, P Guo, L Fang, Y Hu, Q He, B Yang European Journal of Pharmacology 581 (3), 262-269, 2008 | 66 | 2008 |
| The evolution of posttranscriptional regulation B Schaefke, W Sun, YS Li, L Fang, W Chen Wiley Interdisciplinary Reviews: RNA 9 (5), e1485, 2018 | 63 | 2018 |
| Full-length transcriptome reconstruction reveals a large diversity of RNA and protein isoforms in rat hippocampus X Wang, X You, JD Langer, J Hou, F Rupprecht, I Vlatkovic, C Quedenau, ... Nature communications 10 (1), 5009, 2019 | 53 | 2019 |
| Tracing tumorigenesis in a solid tumor model at single-cell resolution SD Praktiknjo, B Obermayer, Q Zhu, L Fang, H Liu, H Quinn, M Stoeckius, ... Nature communications 11 (1), 991, 2020 | 50 | 2020 |
| Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT H Yi, G Li, Y Long, W Liang, H Cui, B Zhang, Y Tan, Y Li, L Shen, D Deng, ... Oncogene 39 (28), 5152-5164, 2020 | 34 | 2020 |
| Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization Q Weng, J Wang, J Wang, J Wang, F Sattar, Z Zhang, J Zheng, Z Xu, ... Cell death & Disease 9 (2), 251, 2018 | 32 | 2018 |
| The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer Q Zhu, L Fang, J Heuberger, A Kranz, J Schipper, K Scheckenbach, ... Cell Reports 26 (2), 415-428. e5, 2019 | 23 | 2019 |
| MZ3 induces apoptosis in human leukemia cells L Fang, Q He, Y Hu, B Yang Cancer chemotherapy and pharmacology 59, 397-405, 2007 | 23 | 2007 |
| A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicing T Chen, B Zhang, T Ziegenhals, AB Prusty, S Fröhler, C Grimm, Y Hu, ... PLoS Genetics 15 (10), e1008460, 2019 | 22 | 2019 |
| CIGAR‐seq, a CRISPR/Cas‐based method for unbiased screening of novel mRNA modification regulators L Fang, W Wang, G Li, L Zhang, J Li, D Gan, J Yang, Y Tang, Z Ding, ... Molecular systems biology 16 (11), e10025, 2020 | 17 | 2020 |
| MZ3 can induce G2/M-phase arrest and apoptosis in human leukemia cells L Fang, L Shen, Y Fang, Y Hu, Q He, B Yang Journal of cancer research and clinical oncology 134, 1337-1345, 2008 | 14 | 2008 |
| CASB: a concanavalin A‐based sample barcoding strategy for single‐cell sequencing L Fang, G Li, Z Sun, Q Zhu, H Cui, Y Li, J Zhang, W Liang, W Wei, Y Hu, ... Molecular systems biology 17 (4), e10060, 2021 | 13 | 2021 |
| Hypoxia-mediated fenretinide (4-HPR) resistance in childhood acute lymphoblastic leukemia cells B Yang, L Fan, L Fang, Q He Cancer chemotherapy and pharmacology 58, 540-546, 2006 | 13 | 2006 |
| CRISPR-iPAS: a novel dCAS13-based method for alternative polyadenylation interference S Tian, B Zhang, Y He, Z Sun, J Li, Y Li, H Yi, Y Zhao, X Zou, Y Li, H Cui, ... Nucleic Acids Research 50 (5), e26-e26, 2022 | 12 | 2022 |
wei chenProfessor of Systems Biology, Southern University of Science and TechnologyVerified email at sustech.edu.cn
