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Lena F Burbulla
Lena F Burbulla
Heisenberg Professor, LMU Munich
Verified email at mail03.med.uni-muenchen.de
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Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13493*2021
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
LF Burbulla, P Song, JR Mazzulli, E Zampese, YC Wong, S Jeon, ...
Science 357 (6357), 1255-1261, 2017
7262017
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression
P Reinhardt, B Schmid, LF Burbulla, DC Schöndorf, L Wagner, M Glatza, ...
Cell stem cell 12 (3), 354-367, 2013
5462013
Functional impairment in miro degradation and mitophagy is a shared feature in familial and sporadic Parkinson’s disease
CH Hsieh, A Shaltouki, AE Gonzalez, AB da Cruz, LF Burbulla, ...
Cell stem cell 19 (6), 709-724, 2016
4352016
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1
G Krebiehl, S Ruckerbauer, LF Burbulla, N Kieper, B Maurer, J Waak, ...
PloS one 5 (2), e9367, 2010
4322010
Activation of β-glucocerebrosidase reduces pathological α-synuclein and restores lysosomal function in Parkinson's patient midbrain neurons
JR Mazzulli, F Zunke, T Tsunemi, NJ Toker, S Jeon, LF Burbulla, ...
Journal of Neuroscience 36 (29), 7693-7706, 2016
2672016
Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis
LF Burbulla, C Schelling, H Kato, D Rapaport, D Woitalla, C Schiesling, ...
Human molecular genetics 19 (22), 4437-4452, 2010
1622010
Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain.
SM Graves, Z Xie, E Zampese, KA Stout, RA Tai, SE Schwarzschild, ...
Nature Neuroscience, 1-6, 2019
1172019
Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1
LF Burbulla, JC Fitzgerald, K Stegen, J Westermeier, AK Thost, H Kato, ...
Cell death & disease 5 (4), e1180-e1180, 2014
1022014
A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson’s disease
LF Burbulla, S Jeon, J Zheng, P Song, RB Silverman, D Krainc
Science translational medicine 11 (514), eaau6870, 2019
962019
Converging environmental and genetic pathways in the pathogenesis of Parkinson's disease
LF Burbulla, R Krüger
Journal of the neurological sciences 306 (1-2), 1-8, 2011
742011
Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function
MJ Kim, S Jeon, LF Burbulla, D Krainc
Human molecular genetics 27 (11), 1972-1988, 2018
672018
Iron overload is accompanied by mitochondrial and lysosomal dysfunction in WDR45 mutant cells
P Seibler, LF Burbulla, M Dulovic, S Zittel, J Heine, T Schmidt, F Rudolph, ...
Brain 141 (10), 3052-3064, 2018
612018
Balance is the challenge–the impact of mitochondrial dynamics in Parkinson’s disease
LF Burbulla, G Krebiehl, R Krüger
European journal of clinical investigation 40 (11), 1048-1060, 2010
612010
Knockdown of Hsc70-5/mortalin induces loss of synaptic mitochondria in a Drosophila Parkinson’s disease model
J Zhu, N Vereshchagina, V Sreekumar, LF Burbulla, AC Costa, KJ Daub, ...
PloS one 8 (12), e83714, 2013
522013
The convergence of alpha-synuclein, mitochondrial, and lysosomal pathways in vulnerability of midbrain dopaminergic neurons in Parkinson’s disease
G Minakaki, D Krainc, LF Burbulla
Frontiers in Cell and Developmental Biology 8, 580634, 2020
482020
Variants in Miro1 cause alterations of ER-mitochondria contact sites in fibroblasts from Parkinson’s disease patients
C Berenguer-Escuder, D Grossmann, F Massart, P Antony, LF Burbulla, ...
Journal of clinical medicine 8 (12), 2226, 2019
442019
Gelator length precisely tunes supramolecular hydrogel stiffness and neuronal phenotype in 3D culture
JM Godbe, R Freeman, LF Burbulla, J Lewis, D Krainc, SI Stupp
ACS biomaterials science & engineering 6 (2), 1196-1207, 2020
432020
A novel heterozygous OPA3 mutation located in the mitochondrial target sequence results in altered steady-state levels and fragmented mitochondrial network
T Grau, LF Burbulla, G Engl, C Delettre, B Delprat, K Oexle, B Leo-Kottler, ...
Journal of medical genetics 50 (12), 848-858, 2013
362013
Interactions of dopamine, iron, and alpha-synuclein linked to dopaminergic neuron vulnerability in Parkinson's disease and Neurodegeneration with Brain Iron Accumulation disorders
RM Wise, A Wagener, UM Fietzek, T Klopstock, EV Mosharov, FA Zucca, ...
Neurobiology of Disease 175, 105920, 2022
352022
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