Nociceptors are interleukin-1β sensors AM Binshtok, H Wang, K Zimmermann, F Amaya, D Vardeh, L Shi, ... Journal of Neuroscience 28 (52), 14062-14073, 2008 | 760 | 2008 |
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence I Tegeder, M Costigan, RS Griffin, A Abele, I Belfer, H Schmidt, C Ehnert, ... Nature medicine 12 (11), 1269-1277, 2006 | 663 | 2006 |
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers AM Binshtok, BP Bean, CJ Woolf Nature 449 (7162), 607-610, 2007 | 523 | 2007 |
BACE1 regulates voltage-gated sodium channels and neuronal activity DY Kim, BW Carey, H Wang, LAM Ingano, AM Binshtok, MH Wertz, ... Nature cell biology 9 (7), 755-764, 2007 | 390 | 2007 |
Voltage-gated sodium channels in pain states: role in pathophysiology and targets for treatment SD Dib-Hajj, AM Binshtok, TR Cummins, MF Jarvis, T Samad, ... Brain research reviews 60 (1), 65-83, 2009 | 188 | 2009 |
TRPM2 mediates neutrophil killing of disseminated tumor cells M Gershkovitz, Y Caspi, T Fainsod-Levi, B Katz, J Michaeli, S Khawaled, ... Cancer research 78 (10), 2680-2690, 2018 | 168 | 2018 |
Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons DP Roberson, S Gudes, JM Sprague, HAW Patoski, VK Robson, F Blasl, ... Nature neuroscience 16 (7), 910-918, 2013 | 163 | 2013 |
Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents AM Binshtok, P Gerner, SB Oh, M Puopolo, S Suzuki, DP Roberson, ... The Journal of the American Society of Anesthesiologists 111 (1), 127-137, 2009 | 146 | 2009 |
Functionally distinct NMDA receptors mediate horizontal connectivity within layer 4 of mouse barrel cortex IA Fleidervish, AM Binshtok, MJ Gutnick Neuron 21 (5), 1055-1065, 1998 | 125 | 1998 |
Targeting of sodium channel blockers into nociceptors to produce long‐duration analgesia: a systematic study and review DP Roberson, AM Binshtok, F Blasl, BP Bean, CJ Woolf British journal of pharmacology 164 (1), 48-58, 2011 | 106 | 2011 |
The role of slow and persistent TTX-resistant sodium currents in acute tumor necrosis factor-α-mediated increase in nociceptors excitability S Gudes, O Barkai, Y Caspi, B Katz, S Lev, AM Binshtok Journal of Neurophysiology 113 (2), 601-619, 2015 | 102 | 2015 |
Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314 M Puopolo, AM Binshtok, GL Yao, SB Oh, CJ Woolf, BP Bean Journal of neurophysiology 109 (7), 1704-1712, 2013 | 94 | 2013 |
NMDA receptors in layer 4 spiny stellate cells of the mouse barrel cortex contain the NR2C subunit AM Binshtok, IA Fleidervish, R Sprengel, MJ Gutnick Journal of Neuroscience 26 (2), 708-715, 2006 | 89 | 2006 |
Capsaicin combined with local anesthetics preferentially prolongs sensory/nociceptive block in rat sciatic nerve P Gerner, AM Binshtok, CF Wang, ND Hevelone, BP Bean, CJ Woolf, ... The Journal of the American Society of Anesthesiologists 109 (5), 872-878, 2008 | 88 | 2008 |
Selectively targeting pain in the trigeminal system HY Kim, K Kim, HY Li, G Chung, CK Park, JS Kim, SJ Jung, MK Lee, ... Pain 150 (1), 29-40, 2010 | 72 | 2010 |
Expression of TRPV1 channels after nerve injury provides an essential delivery tool for neuropathic pain attenuation HM Zakir, RM Mostafeezur, A Suzuki, S Hitomi, I Suzuki, T Maeda, K Seo, ... Public Library of Science 7 (9), e44023, 2012 | 58 | 2012 |
Quaternary lidocaine derivative QX-314 activates and permeates human TRPV1 and TRPA1 to produce inhibition of sodium channels and cytotoxicity T Stueber, MJ Eberhardt, C Hadamitzky, A Jangra, S Schenk, F Dick, ... Anesthesiology 124 (5), 1153-1165, 2016 | 51 | 2016 |
Differential cytotoxicity and intracellular calcium-signalling following activation of the calcium-permeable ion channels TRPV1 and TRPA1 T Stueber, MJ Eberhardt, Y Caspi, S Lev, A Binshtok, A Leffler Cell calcium 68, 34-44, 2017 | 44 | 2017 |
Privileged crosstalk between TRPV1 channels and mitochondrial calcium shuttling machinery controls nociception II Nita, Y Caspi, S Gudes, D Fishman, S Lev, M Hersfinkel, I Sekler, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (12), 2868-2880, 2016 | 41 | 2016 |
KV7/M channels as targets for lipopolysaccharide‐induced inflammatory neuronal hyperexcitability A Tzour, H Leibovich, O Barkai, Y Biala, S Lev, Y Yaari, AM Binshtok The Journal of Physiology 595 (3), 713-738, 2017 | 38 | 2017 |