Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4619 | 2013 |
Candidate gene for the chromosome 1 familial Alzheimer's disease locus E Levy-Lahad, W Wasco, P Poorkaj, DM Romano, J Oshima, ... Science 269 (5226), 973-977, 1995 | 3652 | 1995 |
Synaptic, transcriptional and chromatin genes disrupted in autism S De Rubeis, X He, AP Goldberg, CS Poultney, K Samocha, AE Cicek, ... Nature 515 (7526), 209-215, 2014 | 2895 | 2014 |
Functional impact of global rare copy number variation in autism spectrum disorders D Pinto, AT Pagnamenta, L Klei, R Anney, D Merico, R Regan, J Conroy, ... Nature 466 (7304), 368-372, 2010 | 2368 | 2010 |
Patterns and rates of exonic de novo mutations in autism spectrum disorders BM Neale, Y Kou, L Liu, A Ma’Ayan, KE Samocha, A Sabo, CF Lin, ... Nature 485 (7397), 242-245, 2012 | 2086 | 2012 |
Positional cloning of the Werner's syndrome gene CE Yu, J Oshima, YH Fu, EM Wijsman, F Hisama, R Alisch, S Matthews, ... Science 272 (5259), 258-262, 1996 | 2080 | 1996 |
Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria GU Höglinger, G Respondek, M Stamelou, C Kurz, KA Josephs, AE Lang, ... Movement Disorders 32 (6), 853-864, 2017 | 1930 | 2017 |
Tau is a candidate gene for chromosome 17 frontotemporal dementia P Poorkaj, TD Bird, E Wijsman, E Nemens, RM Garruto, L Anderson, ... Annals of neurology 43 (6), 815-825, 1998 | 1767 | 1998 |
Mapping autism risk loci using genetic linkage and chromosomal rearrangements P Szatmari, A Paterson, L Zwaigenbaum, W Roberts, J Brian, XQ Liu, ... Nature genetics 39 (3), 319, 2007 | 1672* | 2007 |
Autism genome-wide copy number variation reveals ubiquitin and neuronal genes JT Glessner, K Wang, G Cai, O Korvatska, CE Kim, S Wood, H Zhang, ... Nature 459 (7246), 569-573, 2009 | 1632 | 2009 |
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study E Majounie, AE Renton, K Mok, EGP Dopper, A Waite, S Rollinson, ... The Lancet Neurology 11 (4), 323-330, 2012 | 1383 | 2012 |
Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14 GD Schellenberg, TD Bird, EM Wijsman, HT Orr, L Anderson, E Nemens, ... Science 258 (5082), 668-671, 1992 | 1379 | 1992 |
Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17 M Hong, V Zhukareva, V Vogelsberg-Ragaglia, Z Wszolek, L Reed, ... Science 282 (5395), 1914-1917, 1998 | 1227 | 1998 |
Common genetic variants on 5p14. 1 associate with autism spectrum disorders K Wang, H Zhang, D Ma, M Bucan, JT Glessner, BS Abrahams, ... Nature 459 (7246), 528-533, 2009 | 1147 | 2009 |
A framework for the interpretation of de novo mutation in human disease KE Samocha, EB Robinson, SJ Sanders, C Stevens, A Sabo, LM McGrath, ... Nature genetics 46 (9), 944-950, 2014 | 1131 | 2014 |
A familial Alzheimer's disease locus on chromosome 1 E Levy-Lahad, EM Wijsman, E Nemens, L Anderson, KA Goddard, ... Science 269 (5226), 970-973, 1995 | 1130 | 1995 |
Convergence of genes and cellular pathways dysregulated in autism spectrum disorders D Pinto, E Delaby, D Merico, M Barbosa, A Merikangas, L Klei, ... The American Journal of Human Genetics 94 (5), 677-694, 2014 | 1127 | 2014 |
Dementia and Alzheimer disease incidence: a prospective cohort study WA Kukull, R Higdon, JD Bowen, WC McCormick, L Teri, ... Archives of neurology 59 (11), 1737-1746, 2002 | 1041 | 2002 |
TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis VM Van Deerlin, JB Leverenz, LM Bekris, TD Bird, W Yuan, LB Elman, ... The Lancet Neurology 7 (5), 409-416, 2008 | 891 | 2008 |
Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial MW Dysken, M Sano, S Asthana, JE Vertrees, M Pallaki, M Llorente, ... Jama 311 (1), 33-44, 2014 | 772 | 2014 |