עקוב אחר
Vassilios Myrianthopoulos
Vassilios Myrianthopoulos
כתובת אימייל מאומתת בדומיין pharm.uoa.gr
כותרת
צוטט על ידי
צוטט על ידי
שנה
Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases
P Polychronopoulos, P Magiatis, AL Skaltsounis, V Myrianthopoulos, ...
Journal of medicinal chemistry 47 (4), 935-946, 2004
4892004
Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1
N Oumata, K Bettayeb, Y Ferandin, L Demange, A Lopez-Giral, ...
Journal of medicinal chemistry 51 (17), 5229-5242, 2008
1972008
Senescence and senotherapeutics: a new field in cancer therapy
V Myrianthopoulos, K Evangelou, PVS Vasileiou, T Cooks, ...
Pharmacology & therapeutics 193, 31-49, 2019
1702019
Soluble 3′, 6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase-3 alter circadian period
K Vougogiannopoulou, Y Ferandin, K Bettayeb, V Myrianthopoulos, ...
Journal of medicinal chemistry 51 (20), 6421-6431, 2008
1362008
Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining
K Vougas, T Sakellaropoulos, A Kotsinas, GRP Foukas, A Ntargaras, ...
Pharmacology & therapeutics 203, 107395, 2019
1032019
6-Br-5methylindirubin-3′ oxime (5-Me-6-BIO) targeting the leishmanial glycogen synthase kinase-3 (GSK-3) short form affects cell-cycle progression and induces apoptosis-like …
E Xingi, D Smirlis, V Myrianthopoulos, P Magiatis, KM Grant, L Meijer, ...
International journal for parasitology 39 (12), 1289-1303, 2009
872009
Novel inverse binding mode of indirubin derivatives yields improved selectivity for DYRK kinases
V Myrianthopoulos, M Kritsanida, N Gaboriaud-Kolar, P Magiatis, ...
ACS Medicinal Chemistry Letters 4 (1), 22-26, 2013
772013
An integrated computational approach to the phenomenon of potent and selective inhibition of aurora kinases B and C by a series of 7-substituted indirubins
V Myrianthopoulos, P Magiatis, Y Ferandin, AL Skaltsounis, L Meijer, ...
Journal of medicinal chemistry 50 (17), 4027-4037, 2007
732007
Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a …
N Druzhyna, B Szczesny, G Olah, K Módis, A Asimakopoulou, A Pavlidou, ...
Pharmacological research 113, 18-37, 2016
682016
Discovery and optimization of a selective ligand for the switch/sucrose nonfermenting-related bromodomains of polybromo protein-1 by the use of virtual screening and hydration …
V Myrianthopoulos, N Gaboriaud-Kolar, C Tallant, ML Hall, S Grigoriou, ...
Journal of Medicinal Chemistry 59 (19), 8787-8803, 2016
542016
Identification of the substrate recognition and transport pathway in a eukaryotic member of the nucleobase-ascorbate transporter (NAT) family
V Kosti, G Lambrinidis, V Myrianthopoulos, G Diallinas, E Mikros
PLoS One 7 (7), e41939, 2012
532012
Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 transporter
E Krypotou, V Kosti, S Amillis, V Myrianthopoulos, E Mikros, G Diallinas
Journal of Biological Chemistry 287 (44), 36792-36803, 2012
512012
Two new peltogynoids from Acacia nilotica Delile with kinase inhibitory activity
A Ahmadu, A Abdulkarim, R Grougnet, V Myrianthopoulos, F Tillequin, ...
Planta medica 76 (05), 458-460, 2010
512010
Selective cytotoxicity of the herbal substance acteoside against tumor cells and its mechanistic insights
C Cheimonidi, P Samara, P Polychronopoulos, EN Tsakiri, T Nikou, ...
Redox Biology 16, 169-178, 2018
502018
Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation
V Myrianthopoulos, PF Cartron, Z Liutkevičiūtė, S Klimašauskas, ...
European journal of medicinal chemistry 114, 390-396, 2016
482016
An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase 3
A Efstathiou, N Gaboriaud-Kolar, D Smirlis, V Myrianthopoulos, ...
Parasites & vectors 7, 1-12, 2014
412014
Exploring and exploiting the systemic effects of deregulated replication licensing
TG Petrakis, ES Komseli, M Papaioannou, K Vougas, A Polyzos, ...
Seminars in Cancer Biology 37, 3-15, 2016
402016
A substrate translocation trajectory in a cytoplasm‐facing topological model of the monocarboxylate/H+ symporter Jen1p
I Soares‐Silva, J Sá‐Pessoa, V Myrianthopoulos, E Mikros, M Casal, ...
Molecular microbiology 81 (3), 805-817, 2011
312011
Investigating and re-evaluating the role of glycogen synthase kinase 3 beta kinase as a molecular target for cardioprotection by using novel pharmacological inhibitors
PE Nikolaou, K Boengler, P Efentakis, K Vouvogiannopoulou, A Zoga, ...
Cardiovascular research 115 (7), 1228-1243, 2019
292019
The emerging field of senotherapeutic drugs
V Myrianthopoulos
Future medicinal chemistry 10 (20), 2369-2372, 2018
272018
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מאמרים 1–20