| Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle V Sauzeau, H Le Jeune, C Cario-Toumaniantz, A Smolenski, ... Journal of Biological Chemistry 275 (28), 21722-21729, 2000 | 772 | 2000 |
| Rho kinases in cardiovascular physiology and pathophysiology G Loirand, P Guérin, P Pacaud Circulation research 98 (3), 322-334, 2006 | 747 | 2006 |
| Human urotensin II–induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase V Sauzeau, E Le Mellionnec, J Bertoglio, E Scalbert, P Pacaud, G Loirand Circulation research 88 (11), 1102-1104, 2001 | 388 | 2001 |
| The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure C Guilluy, J Brégeon, G Toumaniantz, M Rolli-Derkinderen, K Retailleau, ... Nature medicine 16 (2), 183-190, 2010 | 300 | 2010 |
| Relation between muscarinic receptor cationic current and internal calcium in guinea‐pig jejunal smooth muscle cells. P Pacaud, TB Bolton The Journal of Physiology 441 (1), 477-499, 1991 | 229 | 1991 |
| RhoA expression is controlled by nitric oxide through cGMP-dependent protein kinase activation V Sauzeau, M Rolli-Derkinderen, C Marionneau, G Loirand, P Pacaud Journal of biological chemistry 278 (11), 9472-9480, 2003 | 219 | 2003 |
| RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling C Guilluy, S Eddahibi, C Agard, C Guignabert, M Izikki, L Tu, L Savale, ... American journal of respiratory and critical care medicine 179 (12), 1151-1158, 2009 | 218 | 2009 |
| Rho kinase blockade prevents inflammation via nuclear factor κB inhibition: evidence in Crohn’s disease and experimental colitis JP Segain, DR de la Blétière, V Sauzeau, A Bourreille, G Hilaret, ... Gastroenterology 124 (5), 1180-1187, 2003 | 196 | 2003 |
| The role of Rho protein signaling in hypertension G Loirand, P Pacaud Nature Reviews Cardiology 7 (11), 637-647, 2010 | 190 | 2010 |
| Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells M Rolli-Derkinderen, V Sauzeau, L Boyer, E Lemichez, C Baron, ... Circulation research 96 (11), 1152-1160, 2005 | 189 | 2005 |
| Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension C Guilluy, V Sauzeau, M Rolli‐Derkinderen, P Guérin, C Sagan, ... British journal of pharmacology 146 (7), 1010-1018, 2005 | 185 | 2005 |
| Evidence for two distinct calcium channels in rat vascular smooth muscle cells in short-term primary culture G Loirand, P Pacaud, C Mironneau, J Mironneau Pflügers Archiv 407, 566-568, 1986 | 163 | 1986 |
| Extracellular nucleotides induce arterial smooth muscle cell migration via osteopontin H Chaulet, C Desgranges, MA Renault, F Dupuch, G Ezan, F Peiretti, ... Circulation research 89 (9), 772-778, 2001 | 157 | 2001 |
| Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation Y Gouëffic, C Guilluy, P Guérin, P Patra, P Pacaud, G Loirand Cardiovascular research 72 (2), 339-348, 2006 | 152 | 2006 |
| Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension C Agard, M Rolli‐Derkinderen, E Dumas‐de‐La‐Roque, M Rio, C Sagan, ... British journal of pharmacology 158 (5), 1285-1294, 2009 | 136 | 2009 |
| Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells C Guilluy, M Rolli-Derkinderen, PL Tharaux, G Melino, P Pacaud, ... Journal of biological chemistry 282 (5), 2918-2928, 2007 | 131 | 2007 |
| Small G proteins in the cardiovascular system: physiological and pathological aspects G Loirand, V Sauzeau, P Pacaud Physiological reviews 93 (4), 1659-1720, 2013 | 130 | 2013 |
| P2Y1, P2Y2, P2Y4, and P2Y6 receptors are coupled to Rho and Rho kinase activation in vascular myocytes V Sauzeau, H le Jeune, C Cario-Toumaniantz, N Vaillant, AP Gadeau, ... American Journal of Physiology-Heart and Circulatory Physiology 278 (6 …, 2000 | 128 | 2000 |
| Calcium-activated chloride current in rat vascular smooth muscle cells in short-term primary culture P Pacaud, G Loirand, JL Lavie, C Mironneau, J Mironneau Pflügers Archiv-European Journal of Physiology 413, 629-636, 1989 | 126 | 1989 |
| Structure–activity relationships and structural conformation of a novel urotensin II-related peptide D Chatenet, C Dubessy, J Leprince, C Boularan, L Carlier, ... Peptides 25 (10), 1819-1830, 2004 | 117 | 2004 |
lemichezDépartement de Microbiologie, Institut PasteurVerified email at inserm.fr
