| TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models TR Jay, CM Miller, PJ Cheng, LC Graham, S Bemiller, ML Broihier, G Xu, ... Journal of Experimental Medicine 212 (3), 287-295, 2015 | 693 | 2015 |
| APOE stabilization by exercise prevents aging neurovascular dysfunction and complement induction I Soto, LC Graham, HJ Richter, SN Simeone, JE Radell, W Grabowska, ... PLoS biology 13 (10), e1002279, 2015 | 137 | 2015 |
| Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease LC Graham, JM Harder, I Soto, WN De Vries, SWM John, GR Howell Scientific reports 6 (1), 21568, 2016 | 110 | 2016 |
| Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice GR Howell, I Soto, M Ryan, LC Graham, RS Smith, SWM John Journal of neuroinflammation 10, 1-8, 2013 | 93 | 2013 |
| Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s disease HM Jackson, I Soto, LC Graham, GW Carter, GR Howell BMC genomics 14, 1-12, 2013 | 48 | 2013 |
| Exercise prevents obesity-induced cognitive decline and white matter damage in mice LC Graham, WA Grabowska, Y Chun, SL Risacher, VM Philip, AJ Saykin, ... Neurobiology of aging 80, 154-172, 2019 | 42 | 2019 |
| Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease RS Pandey, L Graham, A Uyar, C Preuss, GR Howell, GW Carter Molecular Neurodegeneration 14, 1-15, 2019 | 38 | 2019 |
| The fetal brain transcriptome and neonatal behavioral phenotype in the Ts1Cje mouse model of Down syndrome F Guedj, JLA Pennings, MA Ferres, LC Graham, HC Wick, KA Miczek, ... American Journal of Medical Genetics Part A 167 (9), 1993-2008, 2015 | 37 | 2015 |
| Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity H Yang, LC Graham, AM Reagan, WA Grabowska, WH Schott, GR Howell Journal of Neuroinflammation 16, 1-18, 2019 | 32 | 2019 |
| DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer’s disease HM Jackson, KD Onos, KW Pepper, LC Graham, EC Akeson, C Byers, ... PloS one 10 (5), e0125897, 2015 | 31 | 2015 |
| Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease I Soto, WA Grabowska, KD Onos, LC Graham, HM Jackson, SN Simeone, ... Neurobiology of aging 42, 50-60, 2016 | 28 | 2016 |
| Deficiency of complement component C1Q prevents cerebrovascular damage and white matter loss in a mouse model of chronic obesity LC Graham, HE Kocalis, I Soto, GR Howell Eneuro 7 (3), 2020 | 10 | 2020 |
| Transcriptional profiling predicts running promotes cerebrovascular remodeling in young but not midlife mice KE Foley, HS Yang, LC Graham, GR Howell BMC genomics 20, 1-14, 2019 | 9 | 2019 |
| The 677C > T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice AM Reagan, KE Christensen, LC Graham, AA Bedwell, K Eldridge, ... Journal of Cerebral Blood Flow & Metabolism 42 (12), 2333-2350, 2022 | 7 | 2022 |
| The Maine Cancer Genomics Initiative: implementing a community cancer genomics program across an entire rural state J Rueter, EC Anderson, LC Graham, A Antov, P Helbig, L Gaitor, J Bourne, ... JCO precision oncology 7, e2200619, 2023 | 3 | 2023 |
| P4‐248: THE ROLE OF TREM2 EXPRESSION ON MYELOID CELLS IN ALZHEIMER'S DISEASE B Lamb, C Miller, T Jay, L Graham, S Bemiller, G Xu, D Margevicius, ... Alzheimer's & Dementia 10, P876-P877, 2014 | 2 | 2014 |
| Genetically modified mouse models of alzheimer's disease G Howell, G Carter, M Sasner, S Rizzo, H Williams, B Lamb, P Territo, ... US Patent App. 17/253,473, 2021 | 1 | 2021 |
| Genome-matched treatments and patient outcomes in the Maine Cancer Genomics Initiative (MCGI) EC Anderson, J DiPalazzo, FL Lucas, MJ Hall, A Antov, P Helbig, ... NPJ Precision Oncology 8 (1), 67, 2024 | | 2024 |
| Mixed-methods analysis of physician genomic confidence in the pre-implementation phase of the cluster randomized trial evaluating genomic tumor boards (SWOG S2108CD, NCT05455606). MS Trivedi, J Rueter, JM Unger, KB Arnold, S Colby, AM Michel, ... JCO Oncology Practice 19 (11_suppl), 439-439, 2023 | | 2023 |
| Transcriptional profiling reveals running promotes cerebrovascular remodeling in young but not aged mice KE Foley, S Yang, LC Graham, GR Howell bioRxiv, 574673, 2019 | | 2019 |
