Ian Mackenzie
Ian Mackenzie
Division of Neuropathology, Department of Pathology and Lab Medicine, University of British Columbia
Verified email at
Cited by
Cited by
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
M Neumann, DM Sampathu, LK Kwong, AC Truax, MC Micsenyi, TT Chou, ...
Science 314 (5796), 130-133, 2006
Inflammation and Alzheimer’s disease
H Akiyama, S Barger, S Barnum, B Bradt, J Bauer, GM Cole, NR Cooper, ...
Neurobiology of aging 21 (3), 383-421, 2000
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
M DeJesus-Hernandez, IR Mackenzie, BF Boeve, AL Boxer, M Baker, ...
Neuron 72 (2), 245-256, 2011
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
M Baker, IR Mackenzie, SM Pickering-Brown, J Gass, R Rademakers, ...
Nature 442 (7105), 916-919, 2006
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature
PT Nelson, I Alafuzoff, EH Bigio, C Bouras, H Braak, NJ Cairns, ...
Journal of Neuropathology & Experimental Neurology 71 (5), 362-381, 2012
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
NJ Cairns, EH Bigio, IRA Mackenzie, M Neumann, VMY Lee, ...
Acta neuropathologica 114, 5-22, 2007
Primary age-related tauopathy (PART): a common pathology associated with human aging
JF Crary, JQ Trojanowski, JA Schneider, JF Abisambra, EL Abner, ...
Acta neuropathologica 128, 755-766, 2014
Pathological TDP‐43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
IRA Mackenzie, EH Bigio, PG Ince, F Geser, M Neumann, NJ Cairns, ...
Annals of Neurology: Official Journal of the American Neurological …, 2007
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update
IRA Mackenzie, M Neumann, EH Bigio, NJ Cairns, I Alafuzoff, J Kril, ...
Acta neuropathologica 119, 1-4, 2010
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
IRA Mackenzie, R Rademakers, M Neumann
The Lancet Neurology 9 (10), 995-1007, 2010
A harmonized classification system for FTLD-TDP pathology
IRA Mackenzie, M Neumann, A Baborie, DM Sampathu, D Du Plessis, ...
Acta neuropathologica 122, 111-113, 2011
ALS‐associated fused in sarcoma (FUS) mutations disrupt Transportin‐mediated nuclear import
D Dormann, R Rodde, D Edbauer, E Bentmann, I Fischer, A Hruscha, ...
The EMBO journal 29 (16), 2841-2857, 2010
A new subtype of frontotemporal lobar degeneration with FUS pathology
M Neumann, R Rademakers, S Roeber, M Baker, HA Kretzschmar, ...
Brain 132 (11), 2922-2931, 2009
Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation
H Lui, J Zhang, SR Makinson, MK Cahill, KW Kelley, HY Huang, Y Shang, ...
Cell 165 (4), 921-935, 2016
Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration
J Gass, A Cannon, IR Mackenzie, B Boeve, M Baker, J Adamson, R Crook, ...
Human molecular genetics 15 (20), 2988-3001, 2006
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
VM Van Deerlin, PMA Sleiman, M Martinez-Lage, A Chen-Plotkin, ...
Nature genetics 42 (3), 234-239, 2010
The heritability and genetics of frontotemporal lobar degeneration
JD Rohrer, R Guerreiro, J Vandrovcova, J Uphill, D Reiman, J Beck, ...
Neurology 73 (18), 1451-1456, 2009
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions
NJ Cairns, M Neumann, EH Bigio, IE Holm, D Troost, KJ Hatanpaa, ...
The American journal of pathology 171 (1), 227-240, 2007
TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics
IR Mackenzie, AM Nicholson, M Sarkar, J Messing, MD Purice, C Pottier, ...
Neuron 95 (4), 808-816. e9, 2017
Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin
F Hu, T Padukkavidana, CB Vægter, OA Brady, Y Zheng, IR Mackenzie, ...
Neuron 68 (4), 654-667, 2010
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