| Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016 | 2177 | 2016 |
| Pan-cancer analysis of whole genomes I The, TPCA of Whole, Genomes Consortium Nature 578 (7793), 82, 2020 | 1522 | 2020 |
| Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library H Koike-Yusa, Y Li, EP Tan, MDC Velasco-Herrera, K Yusa Nature biotechnology 32 (3), 267-273, 2014 | 1220 | 2014 |
| Heterogeneity of genomic evolution and mutational profiles in multiple myeloma N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ... Nature communications 5 (1), 1-13, 2014 | 954 | 2014 |
| Subclonal diversification of primary breast cancer revealed by multiregion sequencing LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ... Nature medicine 21 (7), 751, 2015 | 836 | 2015 |
| MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ... Science 334 (6053), 252-255, 2011 | 733 | 2011 |
| Patterns of somatic structural variation in human cancer genomes Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ... Nature 578 (7793), 112-121, 2020 | 699 | 2020 |
| A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ... Cell reports 17 (4), 1193-1205, 2016 | 636 | 2016 |
| Chromothripsis and kataegis induced by telomere crisis J Maciejowski, Y Li, N Bosco, PJ Campbell, T de Lange Cell 163 (7), 1641-1654, 2015 | 630 | 2015 |
| A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ... Nature 538 (7625), 378-382, 2016 | 554 | 2016 |
| Analyses of non-coding somatic drivers in 2,658 cancer whole genomes E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ... Nature 578 (7793), 102-111, 2020 | 505 | 2020 |
| Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ... Science 345 (6196), 2014 | 438 | 2014 |
| RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia E Papaemmanuil, I Rapado, Y Li, NE Potter, DC Wedge, J Tubio, ... Nature genetics 46 (2), 116-125, 2014 | 404 | 2014 |
| SvABA: genome-wide detection of structural variants and indels by local assembly JA Wala, P Bandopadhayay, NF Greenwald, R O'Rourke, T Sharpe, ... Genome research 28 (4), 581-591, 2018 | 333 | 2018 |
| Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ... Nature genetics 52 (3), 306-319, 2020 | 320 | 2020 |
| Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia Y Li, C Schwab, SL Ryan, E Papaemmanuil, HM Robinson, P Jacobs, ... Nature 508 (7494), 98-102, 2014 | 290 | 2014 |
| Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer KC Akdemir, VT Le, S Chandran, Y Li, RG Verhaak, R Beroukhim, ... Nature genetics 52 (3), 294-305, 2020 | 202 | 2020 |
| Fast and accurate genomic analyses using genome graphs G Rakocevic, V Semenyuk, WP Lee, J Spencer, J Browning, IJ Johnson, ... Nature genetics 51 (2), 354-362, 2019 | 199 | 2019 |
| Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups N Bolli, G Biancon, M Moarii, S Gimondi, Y Li, C de Philippis, F Maura, ... Leukemia 32 (12), 2604-2616, 2018 | 184 | 2018 |
| The linker histone H1. 0 generates epigenetic and functional intratumor heterogeneity CM Torres, A Biran, MJ Burney, H Patel, T Henser-Brownhill, AHS Cohen, ... Science 353 (6307), 2016 | 169 | 2016 |
