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Alessandro Bitto
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Astrocyte senescence as a component of Alzheimer’s disease
R Bhat, EP Crowe, A Bitto, M Moh, CD Katsetos, FU Garcia, FB Johnson, ...
Public Library of Science 7 (9), e45069, 2012
5302012
Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
A Bitto, TK Ito, VV Pineda, NJ LeTexier, HZ Huang, E Sutlief, H Tung, ...
elife 5, e16351, 2016
3862016
Stress-induced senescence in human and rodent astrocytes
A Bitto, C Sell, E Crowe, A Lorenzini, M Malaguti, S Hrelia, C Torres
Experimental cell research 316 (17), 2961-2968, 2010
2002010
Functional mitochondria are required for α-synuclein toxicity in aging yeast
S Buttner, A Bitto, J Ring, M Augsten, P Zabrocki, T Eisenberg, ...
Journal of biological chemistry 283 (12), 7554-7560, 2008
1592008
P62/SQSTM1 at the interface of aging, autophagy, and disease
A Bitto, CA Lerner, T Nacarelli, E Crowe, C Torres, C Sell
Age 36, 1123-1137, 2014
1582014
Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts
C Lerner, A Bitto, D Pulliam, T Nacarelli, M Konigsberg, H Van Remmen, ...
Aging cell 12 (6), 966-977, 2013
1292013
Biochemical genetic pathways that modulate aging in multiple species
A Bitto, AM Wang, CF Bennett, M Kaeberlein
Cold Spring Harbor perspectives in medicine 5 (11), a025114, 2015
1202015
Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice
SC Johnson, M Yanos, M Sangesland, A Bitto, A Gagnidze, J Cordoba, ...
Frontiers in genetics 6, 155155, 2015
902015
Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth
G Monami, V Emiliozzi, A Bitto, F Lovat, SQ Xu, S Goldoni, M Fassan, ...
The American journal of pathology 174 (3), 1037-1047, 2009
902009
Antiaging diets: Separating fact from fiction
MB Lee, CM Hill, A Bitto, M Kaeberlein
Science 374 (6570), eabe7365, 2021
832021
Long-term IGF-I exposure decreases autophagy and cell viability
A Bitto, C Lerner, C Torres, M Roell, M Malaguti, V Perez, A Lorenzini, ...
PloS one 5 (9), e12592, 2010
592010
17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex
DE Harrison, R Strong, P Reifsnyder, N Kumar, E Fernandez, K Flurkey, ...
Aging Cell 20 (5), e13328, 2021
552021
Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans
CF Bennett, JJ Kwon, C Chen, J Russell, K Acosta, N Burnaevskiy, ...
PLoS genetics 13 (3), e1006695, 2017
482017
Proepithelin is an autocrine growth factor for bladder cancer
F Lovat, A Bitto, SQ Xu, M Fassan, S Goldoni, D Metalli, V Wubah, ...
Carcinogenesis 30 (5), 861-868, 2009
462009
SS‐31 and NMN: Two paths to improve metabolism and function in aged hearts
JA Whitson, A Bitto, H Zhang, MT Sweetwyne, R Coig, S Bhayana, ...
Aging Cell 19 (10), e13213, 2020
452020
Rejuvenation: it’s in our blood
A Bitto, M Kaeberlein
Cell metabolism 20 (1), 2-4, 2014
452014
mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases
SC Johnson, F Martinez, A Bitto, B Gonzalez, C Tazaerslan, C Cohen, ...
Kidney international 95 (2), 455-466, 2019
402019
Regional metabolic signatures in the Ndufs4 (KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease
SC Johnson, EB Kayser, R Bornstein, J Stokes, A Bitto, KY Park, A Pan, ...
Molecular genetics and metabolism 130 (2), 118-132, 2020
392020
Design, Synthesis, and Biological Evaluation of Levoglucosenone‐Derived Ras Activation Inhibitors
C Müller, MA Gomez‐Zurita Frau, D Ballinari, S Colombo, A Bitto, ...
ChemMedChem: Chemistry Enabling Drug Discovery 4 (4), 524-528, 2009
342009
Hepatic S6K1 partially regulates lifespan of mice with mitochondrial complex I deficiency
TK Ito, C Lu, J Khan, Q Nguyen, HZ Huang, D Kim, J Phillips, J Tan, Y Lee, ...
Frontiers in genetics 8, 113, 2017
222017
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Articles 1–20