Madsen KL
Madsen KL
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How curved membranes recruit amphipathic helices and protein anchoring motifs
NS Hatzakis, VK Bhatia, J Larsen, KL Madsen, PY Bolinger, AH Kunding, ...
Nature chemical biology 5 (11), 835-841, 2009
Amphipathic motifs in BAR domains are essential for membrane curvature sensing
VK Bhatia, KL Madsen, PY Bolinger, A Kunding, P Hedegård, U Gether, ...
The EMBO journal 28 (21), 3303-3314, 2009
Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD
TS Thorsen, KL Madsen, N Rebola, M Rathje, V Anggono, A Bach, ...
Proceedings of the National Academy of Sciences 107 (1), 413-418, 2010
Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions
C Bjerggaard, JU Fog, H Hastrup, K Madsen, CJ Loland, JA Javitch, ...
Journal of Neuroscience 24 (31), 7024-7036, 2004
BAR domains, amphipathic helices and membrane-anchored proteins use the same mechanism to sense membrane curvature
KL Madsen, VK Bhatia, U Gether, D Stamou
FEBS letters 584 (9), 1848-1855, 2010
GABAA receptor function is regulated by lipid bilayer elasticity
R Søgaard, TM Werge, C Bertelsen, C Lundbye, KL Madsen, CH Nielsen, ...
Biochemistry 45 (43), 13118-13129, 2006
Molecular determinants for the complex binding specificity of the PDZ domain in PICK1
KL Madsen, T Beuming, MY Niv, C Chang, KK Dev, H Weinstein, ...
Journal of Biological Chemistry 280 (21), 20539-20548, 2005
PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance
B Holst, KL Madsen, AM Jansen, C Jin, M Rickhag, VK Lund, M Jensen, ...
PLoS Biol 11 (4), e1001542, 2013
Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1
M Bassan, H Liu, KL Madsen, W Armsen, J Zhou, T DeSilva, W Chen, ...
European Journal of Neuroscience 27 (1), 66-82, 2008
AMPA receptor pHluorin-GluA2 reports NMDA receptor-induced intracellular acidification in hippocampal neurons
M Rathje, H Fang, JL Bachman, V Anggono, U Gether, RL Huganir, ...
Proceedings of the National Academy of Sciences 110 (35), 14426-14431, 2013
A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter
M Rickhag, FH Hansen, G Sørensen, KN Strandfelt, B Andresen, ...
Nature communications 4 (1), 1-14, 2013
Membrane localization is critical for activation of the PICK1 BAR domain
KL Madsen, J Eriksen, L Milan‐Lobo, DS Han, MY Niv, ...
Traffic 9 (8), 1327-1343, 2008
Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway
KL Madsen, TS Thorsen, T Rahbek-Clemmensen, J Eriksen, U Gether
Journal of Biological Chemistry 287 (15), 12293-12308, 2012
Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release
M Rickhag, WA Owens, MT Winkler, KN Strandfelt, M Rathje, G Sørensen, ...
Journal of Biological Chemistry 288 (38), 27534-27544, 2013
Structure–activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1
A Bach, N Stuhr-Hansen, TS Thorsen, N Bork, IS Moreira, K Frydenvang, ...
Organic & biomolecular chemistry 8 (19), 4281-4288, 2010
The BAR domain protein PICK1 controls vesicle number and size in adrenal chromaffin cells
PS Pinheiro, AM Jansen, H de Wit, B Tawfik, KL Madsen, M Verhage, ...
Journal of Neuroscience 34 (32), 10688-10700, 2014
Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands
S Erlendsson, M Rathje, PO Heidarsson, FM Poulsen, KL Madsen, ...
Journal of Biological Chemistry 289 (36), 25327-25340, 2014
Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-ray scattering
ML Karlsen, TS Thorsen, N Johner, I Ammendrup-Johnsen, S Erlendsson, ...
Structure 23 (7), 1258-1270, 2015
Functional modulation of the glutamate transporter variant GLT1b by the PDZ domain protein PICK1
R Sogaard, L Borre, TH Braunstein, KL Madsen, N MacAulay
Journal of Biological Chemistry 288 (28), 20195-20207, 2013
Early stage alpha-synuclein amyloid fibrils are reservoirs of membrane-binding species
T Skamris, C Marasini, KL Madsen, V Foderà, B Vestergaard
Scientific reports 9 (1), 1-11, 2019
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