Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response Q Zhong, CF Chen, S Li, Y Chen, CC Wang, J Xiao, PL Chen, ZD Sharp, ... science 285 (5428), 747-750, 1999 | 844 | 1999 |
Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response S Li, NSY Ting, L Zheng, PL Chen, Y Ziv, Y Shiloh, EYHP Lee, WH Lee Nature 406 (6792), 210-215, 2000 | 432 | 2000 |
Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development. CY Liu, A Flesken-Nikitin, S Li, Y Zeng, WH Lee Genes & development 10 (14), 1835-1843, 1996 | 411 | 1996 |
Telomerase directly regulates NF-κB-dependent transcription A Ghosh, G Saginc, SC Leow, E Khattar, EM Shin, TD Yan, M Wong, ... Nature cell biology 14 (12), 1270-1281, 2012 | 381 | 2012 |
The nuclear localization sequences of the BRCA1 protein interact with the importin-α subunit of the nuclear transport signal receptor CF Chen, S Li, Y Chen, PL Chen, ZD Sharp, WH Lee Journal of Biological Chemistry 271 (51), 32863-32868, 1996 | 316 | 1996 |
Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1 L Zheng, H Pan, S Li, A Flesken-Nikitin, PL Chen, TG Boyer, WH Lee Molecular cell 6 (4), 757-768, 2000 | 311 | 2000 |
Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage S Li, PL Chen, T Subramanian, G Chinnadurai, G Tomlinson, CK Osborne, ... Journal of Biological Chemistry 274 (16), 11334-11338, 1999 | 264 | 1999 |
Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA S Li, JE Rosenberg, AA Donjacour, IL Botchkina, YK Hom, GR Cunha, ... Cancer research 64 (14), 4833-4840, 2004 | 248 | 2004 |
Lessons learned from BRCA1 and BRCA2 L Zheng, S Li, TG Boyer, WH Lee Oncogene 19 (53), 6159-6175, 2000 | 238 | 2000 |
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA S Li, J Crothers, CM Haqq, EH Blackburn Journal of Biological Chemistry 280 (25), 23709-23717, 2005 | 213 | 2005 |
H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions Y Cai, Y Zhang, YP Loh, JQ Tng, MC Lim, Z Cao, A Raju, ... Nature communications 12 (1), 719, 2021 | 176 | 2021 |
Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene MK Ramlee, J Wang, WX Toh, S Li Genes 7 (8), 50, 2016 | 174 | 2016 |
The role of telomere biology in cancer L Xu, S Li, BA Stohr Annual Review of Pathology: Mechanisms of Disease 8, 49-78, 2013 | 169 | 2013 |
Genes and pathways downstream of telomerase in melanoma metastasis S Bagheri, M Nosrati, S Li, S Fong, S Torabian, J Rangel, DH Moore, ... Proceedings of the National Academy of Sciences 103 (30), 11306-11311, 2006 | 167 | 2006 |
Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity CM Koh, E Khattar, SC Leow, CY Liu, J Muller, WX Ang, Y Li, G Franzoso, ... The Journal of clinical investigation 125 (5), 2109-2122, 2015 | 165 | 2015 |
Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs S Li, CY Ku, AA Farmer, YS Cong, CF Chen, WH Lee Journal of Biological Chemistry 273 (11), 6183-6189, 1998 | 158 | 1998 |
Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression S Li, S Makovets, T Matsuguchi, JD Blethrow, KM Shokat, EH Blackburn Cell 136 (1), 50-61, 2009 | 156 | 2009 |
VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma X Yao, J Tan, KJ Lim, J Koh, WF Ooi, Z Li, D Huang, M Xing, YS Chan, ... Cancer discovery 7 (11), 1284-1305, 2017 | 131 | 2017 |
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity WF Ooi, M Xing, C Xu, X Yao, MK Ramlee, MC Lim, F Cao, K Lim, D Babu, ... Nature communications 7 (1), 12983, 2016 | 130 | 2016 |
Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression E Khattar, P Kumar, CY Liu, SC Akıncılar, A Raju, M Lakshmanan, ... The Journal of clinical investigation 126 (10), 4045-4060, 2016 | 127 | 2016 |