Oleg Butovsky
Oleg Butovsky
Associate Professor of Neurology, Harvard Medical School. Principal Investigator.
Verified email at rics.bwh.harvard.edu - Homepage
Cited by
Cited by
Identification of a unique TGF-β–dependent molecular and functional signature in microglia
O Butovsky, MP Jedrychowski, CS Moore, R Cialic, AJ Lanser, G Gabriely, ...
Nature neuroscience 17 (1), 131-143, 2014
Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood
Y Ziv, N Ron, O Butovsky, G Landa, E Sudai, N Greenberg, H Cohen, ...
Nature neuroscience 9 (2), 268-275, 2006
Microglia activated by IL-4 or IFN-γ differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells
O Butovsky, Y Ziv, A Schwartz, G Landa, AE Talpalar, S Pluchino, ...
Molecular and Cellular Neuroscience 31 (1), 149-160, 2006
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases
S Krasemann, C Madore, R Cialic, C Baufeld, N Calcagno, R El Fatimy, ...
Immunity 47 (3), 566-581. e9, 2017
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
H Asai, S Ikezu, S Tsunoda, M Medalla, J Luebke, T Haydar, B Wolozin, ...
Nature neuroscience 18 (11), 1584, 2015
Microglia function in the central nervous system during health and neurodegeneration
M Colonna, O Butovsky
Annual review of immunology 35, 441-468, 2017
Differential roles of microglia and monocytes in the inflamed central nervous system
R Yamasaki, H Lu, O Butovsky, N Ohno, AM Rietsch, R Cialic, PM Wu, ...
Journal of Experimental Medicine 211 (8), 1533-1549, 2014
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
Y Shi, K Yamada, SA Liddelow, ST Smith, L Zhao, W Luo, RM Tsai, ...
Nature 549 (7673), 523-527, 2017
Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion
E Hauben, O Butovsky, U Nevo, E Yoles, G Moalem, E Agranov, F Mor, ...
Journal of Neuroscience 20 (17), 6421-6430, 2000
Microglial phenotype: is the commitment reversible?
M Schwartz, O Butovsky, W Brück, UK Hanisch
Trends in neurosciences 29 (2), 68-74, 2006
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
TR Jay, CM Miller, PJ Cheng, LC Graham, S Bemiller, ML Broihier, G Xu, ...
Journal of Experimental Medicine 212 (3), 287-295, 2015
Activation of microglia by aggregated β-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-γ and IL-4 render them protective
O Butovsky, AE Talpalar, K Ben-Yaakov, M Schwartz
Molecular and Cellular Neuroscience 29 (3), 381-393, 2005
Glatiramer acetate fights against Alzheimer’s disease by inducing dendritic-like microglia expressing insulin-like growth factor 1
O Butovsky, M Koronyo-Hamaoui, G Kunis, E Ophir, G Landa, H Cohen, ...
Proceedings of the National Academy of Sciences 103 (31), 11784-11789, 2006
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
O Butovsky, S Siddiqui, G Gabriely, AJ Lanser, B Dake, G Murugaiyan, ...
The Journal of clinical investigation 122 (9), 3063-3087, 2012
Loss of ‘homeostatic’microglia and patterns of their activation in active multiple sclerosis
T Zrzavy, S Hametner, I Wimmer, O Butovsky, HL Weiner, H Lassmann
Brain 140 (7), 1900-1913, 2017
Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis
O Butovsky, G Landa, G Kunis, Y Ziv, H Avidan, N Greenberg, A Schwartz, ...
The Journal of clinical investigation 116 (4), 905-915, 2006
Targeting mi R‐155 restores abnormal microglia and attenuates disease in SOD 1 mice
O Butovsky, MP Jedrychowski, R Cialic, S Krasemann, G Murugaiyan, ...
Annals of neurology 77 (1), 75-99, 2015
Microglial signatures and their role in health and disease
O Butovsky, HL Weiner
Nature Reviews Neuroscience 19 (10), 622-635, 2018
Vaccination for neuroprotection in the mouse optic nerve: implications for optic neuropathies
J Fisher, H Levkovitch-Verbin, H Schori, E Yoles, O Butovsky, JF Kaye, ...
Journal of Neuroscience 21 (1), 136-142, 2001
Dark microglia: a new phenotype predominantly associated with pathological states
K Bisht, KP Sharma, C Lecours, M Gabriela Sánchez, H El Hajj, G Milior, ...
Glia 64 (5), 826-839, 2016
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