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Hu Meng
Hu Meng
Verified email at pennmedicine.upenn.edu
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Cited by
Year
Motions of allosteric and orthosteric ligand-binding sites in proteins are highly correlated
X Ma, H Meng, L Lai
Journal of Chemical Information and Modeling 56 (9), 1725-1733, 2016
742016
Diverse ways of perturbing the human arachidonic acid metabolic network to control inflammation
H Meng, Y Liu, L Lai
Accounts of chemical research 48 (8), 2242-2250, 2015
682015
Discovery of novel 15-lipoxygenase activators to shift the human arachidonic acid metabolic network toward inflammation resolution
H Meng, CL McClendon, Z Dai, K Li, X Zhang, S He, E Shang, Y Liu, L Lai
Journal of Medicinal Chemistry 59 (9), 4202-4209, 2016
552016
Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion
R Choa, J Tohyama, S Wada, H Meng, J Hu, M Okumura, RM May, ...
Science 373 (6554), eabd2893, 2021
482021
Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives
X Jiang, L Zhou, D Wei, H Meng, Y Liu, L Lai
Bioorganic & medicinal chemistry letters 18 (24), 6549-6552, 2008
352008
Myeloid cell hypoxia-inducible factors promote resolution of inflammation in experimental colitis
N Lin, JES Shay, H Xie, DSM Lee, N Skuli, Q Tang, Z Zhou, A Azzam, ...
Frontiers in immunology 9, 2565, 2018
332018
Molecular mechanism of 15-lipoxygenase allosteric activation and inhibition
H Meng, Z Dai, W Zhang, Y Liu, L Lai
Physical Chemistry Chemical Physics 20 (21), 14785-14795, 2018
252018
Genomic and lipidomic analyses differentiate the compensatory roles of two COX isoforms during systemic inflammation in mice 1, 2 [S]
X Li, LL Mazaleuskaya, LL Ballantyne, H Meng, GA FitzGerald, CD Funk
Journal of lipid research 59 (1), 102-112, 2018
222018
A novel allosteric inhibitor that prevents IKKβ activation
H Liu, H Liang, H Meng, X Deng, X Zhang, L Lai
Medchemcomm 9 (2), 239-243, 2018
152018
Flipping the cyclooxygenase (Ptgs) genes reveals isoform-specific compensatory functions 1, 2 [S]
X Li, LL Mazaleuskaya, C Yuan, LL Ballantyne, H Meng, WL Smith, ...
Journal of Lipid Research 59 (1), 89-101, 2018
142018
Cyclooxygenase-2, asymmetric dimethylarginine, and the cardiovascular hazard from nonsteroidal anti-inflammatory drugs
E Ricciotti, C Castro, SY Tang, WTE Briggs, JA West, D Malik, ...
Circulation 138 (21), 2367-2378, 2018
132018
Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase
H Meng, Y Liu, Y Zhai, L Lai
European Journal of Medicinal Chemistry 59, 160-167, 2013
122013
Sexual dimorphism in the response to chronic circadian misalignment on a high-fat diet
ST Anderson, H Meng, TG Brooks, SY Tang, R Lordan, A Sengupta, ...
Science Translational Medicine 15 (696), eabo2022, 2023
112023
Considerations for the safe operation of schools during the coronavirus pandemic
R Lordan, S Prior, E Hennessy, A Naik, S Ghosh, GK Paschos, C Skarke, ...
Frontiers in public health 9, 751451, 2021
112021
Deep phenotyping of the lipidomic response in COVID‐19 and non‐COVID‐19 sepsis
H Meng, A Sengupta, E Ricciotti, A Mrčela, D Mathew, LL Mazaleuskaya, ...
Clinical and Translational Medicine 13 (11), e1440, 2023
52023
Differential compensation of two cyclooxygenases in renal homeostasis is independent of prostaglandin-synthetic capacity under basal conditions
X Li, LL Mazaleuskaya, LL Ballantyne, H Meng, GA FitzGerald, CD Funk
The FASEB Journal 32 (10), 5326, 2018
42018
Identification of 1, 4‐Dihydrothieno [3′, 2′: 5, 6] thiopyrano [4, 3‐c] pyrazole Derivatives as Human 5‐Lipo‐oxygenase Inhibitors
J Hu, W Zhu, H Meng, Y Liu, X Wang, C Hu
Chemical Biology & Drug Design 84 (6), 642-647, 2014
42014
Nonsteroidal anti-inflammatory drugs as a targeted therapy for bone marrow failure in Ghosal hematodiaphyseal dysplasia
TJ Brown, N Barrett, H Meng, E Ricciotti, C McDonnell, A Dancis, ...
Blood 141 (13), 1553-1559, 2023
32023
The role of thymic stromal lymphopoietin (TSLP) in protection from type II diabetes
R Choa, S Wada, H Meng, RAL Pai, M Okumura, J Tohyama, A Nace, ...
The Journal of Immunology 204 (1_Supplement), 145.8-145.8, 2020
32020
Modulation of the immune response to severe acute respiratory syndrome coronavirus 2 vaccination by nonsteroidal anti-inflammatory drugs
C Skarke, R Lordan, K Barekat, A Naik, D Mathew, T Ohtani, ...
Journal of Pharmacology and Experimental Therapeutics 386 (2), 198-204, 2023
22023
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