Don Kirkpatrick
Don Kirkpatrick
CTO, Interline Therapeutics
Verified email at - Homepage
Cited by
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The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
B Bingol, JS Tea, L Phu, M Reichelt, CE Bakalarski, Q Song, O Foreman, ...
Nature 510 (7505), 370-375, 2014
The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications
DS Kirkpatrick, SA Gerber, SP Gygi
Methods 35 (3), 265-273, 2005
Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain
F Huang, D Kirkpatrick, X Jiang, S Gygi, A Sorkin
Molecular cell 21 (6), 737-748, 2006
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies
K Newton, ML Matsumoto, IE Wertz, DS Kirkpatrick, JR Lill, J Tan, ...
Cell 134 (4), 668-678, 2008
Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases
JMM Tan, ESP Wong, DS Kirkpatrick, O Pletnikova, HS Ko, SP Tay, ...
Human molecular genetics 17 (3), 431-439, 2008
Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology
DS Kirkpatrick, NA Hathaway, J Hanna, S Elsasser, J Rush, D Finley, ...
Nature cell biology 8 (7), 700-710, 2006
K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody
ML Matsumoto, KE Wickliffe, KC Dong, C Yu, I Bosanac, D Bustos, L Phu, ...
Molecular cell 39 (3), 477-484, 2010
Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome
CJ Westlake, LM Baye, MV Nachury, KJ Wright, KE Ervin, L Phu, ...
Proceedings of the National Academy of Sciences 108 (7), 2759-2764, 2011
Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation
J Hanna, NA Hathaway, Y Tone, B Crosas, S Elsasser, DS Kirkpatrick, ...
Cell 127 (1), 99-111, 2006
Loss of the tumor suppressor BAP1 causes myeloid transformation
A Dey, D Seshasayee, R Noubade, DM French, J Liu, MS Chaurushiya, ...
Science 337 (6101), 1541-1546, 2012
c‐IAP1 and UbcH5 promote K11‐linked polyubiquitination of RIP1 in TNF signalling
JN Dynek, T Goncharov, EC Dueber, AV Fedorova, A Izrael‐Tomasevic, ...
The EMBO journal 29 (24), 4198-4209, 2010
Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations
Z Sheng, S Zhang, D Bustos, T Kleinheinz, CE Le Pichon, SL Dominguez, ...
Science translational medicine 4 (164), 164ra161-164ra161, 2012
Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities
B Crosas, J Hanna, DS Kirkpatrick, DP Zhang, Y Tone, NA Hathaway, ...
Cell 127 (7), 1401-1413, 2006
USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
CN Cunningham, JM Baughman, L Phu, JS Tea, C Yu, M Coons, ...
Nature cell biology 17 (2), 160-169, 2015
Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics
DS Kirkpatrick, C Denison, SP Gygi
Nature cell biology 7 (8), 750-757, 2005
Discovery of novel blood-brain barrier targets to enhance brain uptake of therapeutic antibodies
YJY Zuchero, X Chen, N Bien-Ly, D Bumbaca, RK Tong, X Gao, S Zhang, ...
Neuron 89 (1), 70-82, 2016
Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling
MG Callow, H Tran, L Phu, T Lau, J Lee, WN Sandoval, PS Liu, ...
PloS one 6 (7), e22595, 2011
Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling
I Bosanac, IE Wertz, B Pan, C Yu, S Kusam, C Lam, L Phu, Q Phung, ...
Molecular cell 40 (4), 548-557, 2010
APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1
NV Dimova, NA Hathaway, BH Lee, DS Kirkpatrick, ML Berkowitz, ...
Nature cell biology 14 (2), 168-176, 2012
A novel acetylation of β-tubulin by San modulates microtubule polymerization via down-regulating tubulin incorporation
CW Chu, F Hou, J Zhang, L Phu, AV Loktev, DS Kirkpatrick, PK Jackson, ...
Molecular biology of the cell 22 (4), 448-456, 2011
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