| Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. RY Hampton, RG Gardner, J Rine Molecular biology of the cell 7 (12), 2029-2044, 1996 | 675 | 1996 |
| Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation NW Bays, RG Gardner, LP Seelig, CA Joazeiro, RY Hampton Nature cell biology 3 (1), 24-29, 2001 | 572 | 2001 |
| Endoplasmic reticulum degradation requires lumen to cytosol signaling: transmembrane control of Hrd1p by Hrd3p RG Gardner, GM Swarbrick, NW Bays, SR Cronin, S Wilhovsky, L Seelig, ... The Journal of cell biology 151 (1), 69-82, 2000 | 386 | 2000 |
| Degradation-mediated protein quality control in the nucleus RG Gardner, ZW Nelson, DE Gottschling Cell 120 (6), 803-815, 2005 | 326 | 2005 |
| Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates JC Rosenbaum, EK Fredrickson, ML Oeser, CM Garrett-Engele, ... Molecular cell 41 (1), 93-106, 2011 | 213 | 2011 |
| Ubp10/Dot4p regulates the persistence of ubiquitinated histone H2B: distinct roles in telomeric silencing and general chromatin RG Gardner, ZW Nelson, DE Gottschling Molecular and cellular biology, 2005 | 196 | 2005 |
| A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes RG Gardner, RY Hampton Journal of biological chemistry 274 (44), 31671-31678, 1999 | 184 | 1999 |
| Cotrafficking of SV2 and synaptotagmin at the synapse J Yao, A Nowack, P Kensel-Hammes, RG Gardner, SM Bajjalieh Journal of Neuroscience 30 (16), 5569-5578, 2010 | 171 | 2010 |
| In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation RG Gardner, AG Shearer, RY Hampton Molecular and cellular biology, 2001 | 152 | 2001 |
| α-Arrestins Aly1 and Aly2 regulate intracellular trafficking in response to nutrient signaling AF O'Donnell, A Apffel, RG Gardner, MS Cyert Molecular biology of the cell 21 (20), 3552-3566, 2010 | 132 | 2010 |
| HRD Gene Dependence of Endoplasmic Reticulum-associated Degradation S Wilhovsky, R Gardner, R Hampton Molecular biology of the cell 11 (5), 1697-1708, 2000 | 128 | 2000 |
| Exposed hydrophobicity is a key determinant of nuclear quality control degradation EK Fredrickson, JC Rosenbaum, MN Locke, TI Milac, RG Gardner Molecular biology of the cell 22 (13), 2384-2395, 2011 | 122 | 2011 |
| Use of a modified Bacteroides-Prevotella shuttle vector to transfer a reconstructed beta-1, 4-D-endoglucanase gene into Bacteroides uniformis and Prevotella ruminicola B (1) 4 RG Gardner, JB Russell, DB Wilson, GR Wang, NB Shoemaker Applied and environmental microbiology 62 (1), 196-202, 1996 | 119 | 1996 |
| A ‘distributed degron’allows regulated entry into the ER degradation pathway RG Gardner, RY Hampton The EMBO Journal, 1999 | 106 | 1999 |
| Sequence determinants for regulated degradation of yeast 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein R Gardner, S Cronin, B Leader, J Rine, R Hampton Molecular biology of the cell 9 (9), 2611-2626, 1998 | 91 | 1998 |
| Selective destruction of abnormal proteins by ubiquitin-mediated protein quality control degradation EK Fredrickson, RG Gardner Seminars in cell & developmental biology 23 (5), 530-537, 2012 | 75 | 2012 |
| A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability LA Richardson, BJ Reed, JM Charette, EF Freed, EK Fredrickson, ... Cell reports 2 (2), 372-385, 2012 | 71 | 2012 |
| Protein quality control degradation in the nucleus C Enam, Y Geffen, T Ravid, RG Gardner Annual Review of Biochemistry 87, 725-749, 2018 | 70 | 2018 |
| The Recruitment of the Saccharomyces cerevisiae Paf1 Complex to Active Genes Requires a Domain of Rtf1 That Directly Interacts with the Spt4-Spt5 Complex MK Mayekar, RG Gardner, KM Arndt Molecular and cellular biology 33 (16), 3259-3273, 2013 | 69 | 2013 |
| Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin CG Amrich, CP Davis, WP Rogal, MK Shirra, A Heroux, RG Gardner, ... Journal of Biological Chemistry 287 (14), 10863-10875, 2012 | 69 | 2012 |
