עקוב אחר
Eyal Gottlieb
Eyal Gottlieb
The University of Texas, MD Anderson Cancer Center
כתובת אימייל מאומתת בדומיין mdanderson.org
כותרת
צוטט על ידי
צוטט על ידי
שנה
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
53912018
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ...
Nature 496 (7444), 238-242, 2013
34052013
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
L Galluzzi, I Vitale, JM Abrams, ES Alnemri, EH Baehrecke, ...
Cell Death & Differentiation 19 (1), 107-120, 2012
31362012
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
K Bensaad, A Tsuruta, MA Selak, MNC Vidal, K Nakano, R Bartrons, ...
Cell 126 (1), 107-120, 2006
23742006
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
MA Selak, SM Armour, ED MacKenzie, H Boulahbel, DG Watson, ...
Cancer cell 7 (1), 77-85, 2005
23122005
Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages
EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ...
Cell 167 (2), 457-470. e13, 2016
16622016
Targeting metabolic transformation for cancer therapy
DA Tennant, RV Durán, E Gottlieb
Nature reviews cancer 10 (4), 267-277, 2010
12732010
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
ODK Maddocks, CR Berkers, SM Mason, L Zheng, K Blyth, E Gottlieb, ...
Nature 493 (7433), 542-546, 2013
9552013
Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer
A King, MA Selak, E Gottlieb
Oncogene 25 (34), 4675-4682, 2006
8592006
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation
M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ...
Cell metabolism 18 (5), 698-711, 2013
7992013
Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis
E Gottlieb, SM Armour, MH Harris, CB Thompson
Cell Death & Differentiation 10 (6), 709-717, 2003
7972003
Mitochondrial tumour suppressors: a genetic and biochemical update
E Gottlieb, IPM Tomlinson
Nature Reviews Cancer 5 (11), 857-866, 2005
7772005
p53 status determines the role of autophagy in pancreatic tumour development
MT Rosenfeldt, J O’Prey, JP Morton, C Nixon, G MacKay, A Mrowinska, ...
Nature 504 (7479), 296-300, 2013
7232013
Glutaminolysis activates Rag-mTORC1 signaling
RV Durán, W Oppliger, AM Robitaille, L Heiserich, R Skendaj, E Gottlieb, ...
Molecular cell 47 (3), 349-358, 2012
7222012
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
ZT Schug, B Peck, DT Jones, Q Zhang, S Grosskurth, IS Alam, ...
Cancer cell 27 (1), 57-71, 2015
7042015
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
B Chaneton, P Hillmann, L Zheng, ACL Martin, ODK Maddocks, ...
Nature 491 (7424), 458-462, 2012
6622012
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
J Kaplon, L Zheng, K Meissl, B Chaneton, VA Selivanov, G Mackay, ...
Nature 498 (7452), 109-112, 2013
6292013
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
6092015
Predicting selective drug targets in cancer through metabolic networks
O Folger, L Jerby, C Frezza, E Gottlieb, E Ruppin, T Shlomi
Molecular systems biology 7 (1), 501, 2011
5872011
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
C Frezza, L Zheng, O Folger, KN Rajagopalan, ED MacKenzie, L Jerby, ...
Nature 477 (7363), 225-228, 2011
5432011
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מאמרים 1–20