Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation L Cegelski, JS Pinkner, ND Hammer, CK Cusumano, CS Hung, E Chorell, ... Nature chemical biology 5 (12), 913-919, 2009 | 491 | 2009 |
Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria JS Pinkner, H Remaut, F Buelens, E Miller, V Åberg, N Pemberton, ... Proceedings of the National Academy of Sciences 103 (47), 17897-17902, 2006 | 366 | 2006 |
The bacterial curli system possesses a potent and selective inhibitor of amyloid formation ML Evans, E Chorell, JD Taylor, J Åden, A Götheson, F Li, M Koch, ... Molecular cell 57 (3), 445-455, 2015 | 219 | 2015 |
Design and evaluation of pilicides: potential novel antibacterial agents directed against uropathogenic Escherichia coli A Svensson, A Larsson, H Emtenäs, M Hedenström, T Fex, SJ Hultgren, ... ChemBioChem (Print) 2 (12), 915-918, 2001 | 171 | 2001 |
Promiscuous cross-seeding between bacterial amyloids promotes interspecies biofilms Y Zhou, D Smith, BJ Leong, K Brännström, F Almqvist, MR Chapman Journal of Biological Chemistry 287 (42), 35092-35103, 2012 | 145 | 2012 |
Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation I Horvath, CF Weise, EK Andersson, E Chorell, M Sellstedt, C Bengtsson, ... Journal of the American Chemical Society 134 (7), 3439-3444, 2012 | 141 | 2012 |
Synthesis of 2-Substituted Pyridines via a Regiospecific Alkylation, Alkynylation, and Arylation of Pyridine N-Oxides H Andersson, F Almqvist, R Olsson Organic Letters 9 (7), 1335-1337, 2007 | 135 | 2007 |
Pilicides—small molecules targeting bacterial virulence V Åberg, F Almqvist Organic & biomolecular chemistry 5 (12), 1827-1834, 2007 | 133 | 2007 |
An enantioselective ketene− imine cycloaddition method for synthesis of substituted ring-fused 2-pyridinones H Emtenäs, L Alderin, F Almqvist The Journal of organic chemistry 66 (20), 6756-6761, 2001 | 122 | 2001 |
Pathogenic H elicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system MG Varga, CL Shaffer, JC Sierra, G Suarez, MB Piazuelo, ME Whitaker, ... Oncogene 35 (48), 6262-6269, 2016 | 118 | 2016 |
Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity E Chorell, JS Pinkner, G Phan, S Edvinsson, F Buelens, H Remaut, ... Journal of medicinal chemistry 53 (15), 5690-5695, 2010 | 113 | 2010 |
Adhesive Fiber Stratification in Uropathogenic Escherichia coli Biofilms Unveils Oxygen-Mediated Control of Type 1 Pili KA Floyd, JL Moore, AR Eberly, JAD Good, CL Shaffer, H Zaver, ... PLoS pathogens 11 (3), e1004697, 2015 | 99 | 2015 |
T cells recognize a glycopeptide derived from type II collagen in a model for rheumatoid arthritis J Broddefalk, J Bäcklund, F Almqvist, M Johansson, R Holmdahl, ... Journal of the American Chemical Society 120 (31), 7676-7683, 1998 | 99 | 1998 |
Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria M Hall, C Grundström, A Begum, MJ Lindberg, UH Sauer, F Almqvist, ... Proceedings of the National Academy of Sciences 113 (51), 14733-14738, 2016 | 89 | 2016 |
Targeting virulence for antimicrobial chemotherapy YM Lee, F Almqvist, SJ Hultgren Current opinion in pharmacology 3 (5), 513-519, 2003 | 87 | 2003 |
New Ligands for the Titanium (IV)‐Induced Asymmetric Reduction of Ketones with Catecholborane F Almqvist, L Torstensson, A Gudmundsson, T Frejd Angewandte Chemie International Edition in English 36 (4), 376-377, 1997 | 87 | 1997 |
Design and parallel solid-phase synthesis of ring-fused 2-pyridinones that target pilus biogenesis in pathogenic bacteria H Emtenäs, K Åhlin, JS Pinkner, SJ Hultgren, F Almqvist Journal of combinatorial chemistry 4 (6), 630-639, 2002 | 84 | 2002 |
The C-terminal repeating units of CsgB direct bacterial functional amyloid nucleation ND Hammer, BA McGuffie, Y Zhou, MP Badtke, AA Reinke, K Brännström, ... Journal of molecular biology 422 (3), 376-389, 2012 | 83 | 2012 |
Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli SE Greene, JS Pinkner, E Chorell, KW Dodson, CL Shaffer, MS Conover, ... MBio 5 (6), 10.1128/mbio. 02038-14, 2014 | 79 | 2014 |
Asymmetric Reduction of Ketones with Catecholborane Using 2,6‐BODOL Complexes of Titanium(IV) as Catalysts I Sarvary, F Almqvist, T Frejd Chemistry–A European Journal 7 (10), 2158-2166, 2001 | 79 | 2001 |