עקוב אחר
Wouter Karthaus
Wouter Karthaus
EPFL SV ISREC
כתובת אימייל מאומתת בדומיין epfl.ch
כותרת
צוטט על ידי
צוטט על ידי
שנה
Organoid cultures derived from patients with advanced prostate cancer‏
D Gao, I Vela, A Sboner, PJ Iaquinta, WR Karthaus, A Gopalan, ...‏
Cell 159 (1), 176-187, 2014‏
14612014
Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex‏
VSW Li, SS Ng, PJ Boersema, TY Low, WR Karthaus, JP Gerlach, ...‏
Cell 149 (6), 1245-1256, 2012‏
10072012
SOX2 promotes lineage plasticity and antiandrogen resistance in TP53-and RB1-deficient prostate cancer‏
P Mu, Z Zhang, M Benelli, WR Karthaus, E Hoover, CC Chen, ...‏
Science 355 (6320), 84-88, 2017‏
8932017
Identification of multipotent luminal progenitor cells in human prostate organoid cultures‏
WR Karthaus, PJ Iaquinta, J Drost, A Gracanin, R Van Boxtel, J Wongvipat, ...‏
Cell 159 (1), 163-175, 2014‏
7182014
Organoid culture systems for prostate epithelial and cancer tissue‏
J Drost, WR Karthaus, D Gao, E Driehuis, CL Sawyers, Y Chen, H Clevers‏
Nature protocols 11 (2), 347-358, 2016‏
5742016
Efficient intracellular delivery of native proteins‏
DS D’Astolfo, RJ Pagliero, A Pras, WR Karthaus, H Clevers, V Prasad, ...‏
Cell 161 (3), 674-690, 2015‏
3832015
A rectal cancer organoid platform to study individual responses to chemoradiation‏
K Ganesh, C Wu, KP O’Rourke, BC Szeglin, Y Zheng, CEG Sauvé, ...‏
Nature medicine 25 (10), 1607-1614, 2019‏
3722019
Genome sequencing of normal cells reveals developmental lineages and mutational processes‏
S Behjati, M Huch, R Van Boxtel, W Karthaus, DC Wedge, AU Tamuri, ...‏
Nature 513 (7518), 422-425, 2014‏
3702014
Controlled gene expression in primary Lgr5 organoid cultures‏
BK Koo, DE Stange, T Sato, W Karthaus, HF Farin, M Huch, JH Van Es, ...‏
Nature methods 9 (1), 81-83, 2012‏
3632012
Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon‏
N Sasaki, N Sachs, K Wiebrands, SIJ Ellenbroek, A Fumagalli, ...‏
Proceedings of the National Academy of Sciences 113 (37), E5399-E5407, 2016‏
3352016
The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells‏
DJ Vander Griend, WL Karthaus, S Dalrymple, A Meeker, AM DeMarzo, ...‏
Cancer research 68 (23), 9703-9711, 2008‏
3052008
Patient derived organoids to model rare prostate cancer phenotypes‏
L Puca, R Bareja, D Prandi, R Shaw, M Benelli, WR Karthaus, J Hess, ...‏
Nature communications 9 (1), 2404, 2018‏
2992018
Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell–derived IFN-γ‏
HF Farin, WR Karthaus, P Kujala, M Rakhshandehroo, G Schwank, ...‏
Journal of Experimental Medicine 211 (7), 1393-1405, 2014‏
2862014
Regenerative potential of prostate luminal cells revealed by single-cell analysis‏
WR Karthaus, M Hofree, D Choi, EL Linton, M Turkekul, A Bejnood, ...‏
Science 368 (6490), 497-505, 2020‏
2002020
FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes‏
EJ Adams, WR Karthaus, E Hoover, D Liu, A Gruet, Z Zhang, H Cho, ...‏
Nature 571 (7765), 408-412, 2019‏
1962019
Tumor microenvironment-derived NRG1 promotes antiandrogen resistance in prostate cancer‏
Z Zhang, WR Karthaus, YS Lee, VR Gao, C Wu, JW Russo, M Liu, ...‏
Cancer Cell 38 (2), 279-296. e9, 2020‏
1692020
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer‏
N Shah, P Wang, J Wongvipat, WR Karthaus, W Abida, J Armenia, ...‏
Elife 6, e27861, 2017‏
1642017
Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling‏
JM Chan, S Zaidi, JR Love, JL Zhao, M Setty, KM Wadosky, A Gopalan, ...‏
Science 377 (6611), 1180-1191, 2022‏
1172022
ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis‏
R Bose, WR Karthaus, J Armenia, W Abida, PJ Iaquinta, Z Zhang, ...‏
Nature 546 (7660), 671-675, 2017‏
822017
FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer‏
A Arruabarrena-Aristorena, JLV Maag, S Kittane, Y Cai, WR Karthaus, ...‏
Cancer cell 38 (4), 534-550. e9, 2020‏
772020
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מאמרים 1–20