עקוב אחר
Helena Coelho
Helena Coelho
UCIBIO
כתובת אימייל מאומתת בדומיין campus.fct.unl.pt
כותרת
צוטט על ידי
צוטט על ידי
שנה
Structural characterization of N‐linked glycans in the receptor binding domain of the SARS‐CoV‐2 spike protein and their interactions with human lectins
MP Lenza, I Oyenarte, T Diercks, JI Quintana, A Gimeno, H Coelho, ...
Angewandte Chemie 132 (52), 23971-23979, 2020
872020
Delineating Binding Modes of Gal/GalNAc and Structural Elements of the Molecular Recognition of Tumor‐Associated Mucin Glycopeptides by the Human Macrophage Galactose‐Type Lectin
F Marcelo, F Garcia‐Martin, T Matsushita, J Sardinha, H Coelho, ...
Chemistry–A European Journal 20 (49), 16147-16155, 2014
672014
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3
M de las Rivas, EJP Daniel, Y Narimatsu, I Compañón, K Kato, ...
Nature Chemical Biology, 2020
572020
Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition
D Madariaga, N Martinez-Saez, VJ Somovilla, H Coelho, ...
ACS chemical biology 10 (3), 747-756, 2015
472015
The quest for anticancer vaccines: Deciphering the fine-epitope specificity of cancer-related monoclonal antibodies by combining microarray screening and Saturation Transfer …
H Coelho, T Matsushita, G Artigas, H Hinou, FJ Cañada, R Lo-Man, ...
Journal of the American Chemical Society 137 (39), 12438-12441, 2015
412015
The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences
M De Las Rivas, E Lira-Navarrete, EJP Daniel, I Compañón, H Coelho, ...
Nature communications 8 (1), 1959, 2017
402017
Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4
M De Las Rivas, EJ Paul Daniel, H Coelho, E Lira-Navarrete, L Raich, ...
ACS central science 4 (9), 1274-1290, 2018
372018
Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties
F Cochet, FA Facchini, L Zaffaroni, JM Billod, H Coelho, A Holgado, ...
Scientific reports 9 (1), 919, 2019
312019
The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose‐Type Lectin
A Diniz, H Coelho, JS Dias, SJ van Vliet, J Jiménez‐Barbero, F Corzana, ...
Chemistry–A European Journal 25 (61), 13945-13955, 2019
292019
Crystal structure of the carbohydrate recognition domain of the human macrophage galactose C-type lectin bound to GalNAc and the tumor-associated Tn antigen
A Gabba, A Bogucka, JG Luz, A Diniz, H Coelho, F Corzana, FJ Cañada, ...
Biochemistry 60 (17), 1327-1336, 2021
222021
Structural Analysis of a GalNAc‐T2 Mutant Reveals an Induced‐Fit Catalytic Mechanism for GalNAc‐Ts
M de Las Rivas, H Coelho, A Diniz, E Lira‐Navarrete, I Compañón, ...
Chemistry–A European Journal 24 (33), 8382-8392, 2018
212018
Glycans in infectious diseases. A molecular recognition perspective
L Unione, A Gimeno, P Valverde, I Calloni, H Coelho, S Mirabella, ...
Current medicinal chemistry 24 (36), 4057-4080, 2017
212017
Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
H Coelho, M Rivas, AS Grosso, A Diniz, CO Soares, RA Francisco, ...
JACS Au 2 (3), 631-645, 2022
132022
Molecular Recognition Insights of Sialic Acid Glycans by Distinct Receptors Unveiled by NMR and Molecular Modeling
CO Soares, AS Grosso, J Ereño-Orbea, H Coelho, F Marcelo
Frontiers in Molecular Biosciences 8, 727847, 2021
132021
Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody
J Macías-León, IA Bermejo, A Asín, A García-García, I Compañón, ...
Chemical Communications 56 (96), 15137-15140, 2020
112020
Co‐administration of Antimicrobial Peptides Enhances Toll‐like Receptor 4 Antagonist Activity of a Synthetic Glycolipid
FA Facchini, H Coelho, SE Sestito, S Delgado, A Minotti, D Andreu, ...
ChemMedChem 13 (3), 280-287, 2018
82018
Peptidomimetic β-secretase inhibitors comprising a sequence of amyloid-β peptide for Alzheimer’s disease
H Vila-Real, H Coelho, J Rocha, A Fernandes, MR Ventura, CD Maycock, ...
Journal of medicinal chemistry 58 (14), 5408-5418, 2015
82015
Structural basis for the synthesis of the core 1 structure by C1GalT1
AM González-Ramírez, AS Grosso, Z Yang, I Compañón, H Coelho, ...
Nature Communications 13 (1), 2398, 2022
72022
Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody
MP Lenza, U Atxabal, C Nycholat, I Oyenarte, A Franconetti, JI Quintana, ...
JACS Au 3 (1), 204-215, 2022
62022
Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune‐Related Lectins
CDL Lima, H Coelho, A Gimeno, F Trovão, A Diniz, JS Dias, ...
Chemistry–A European Journal 27 (29), 7951-7958, 2021
62021
המערכת אינה יכולה לבצע את הפעולה כעת. נסה שוב מאוחר יותר.
מאמרים 1–20