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Luke Pennington
Luke Pennington
Verified email at stanford.edu
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Year
Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange
LF Pennington, S Tarchevskaya, D Brigger, K Sathiyamoorthy, ...
Nature communications 7 (1), 11610, 2016
1052016
Accuracy of serological testing for SARS‐CoV‐2 antibodies: first results of a large mixed‐method evaluation study
D Brigger, MP Horn, LF Pennington, AE Powell, D Siegrist, B Weber, ...
Allergy 76 (3), 853-865, 2021
362021
H-IPSE is a pathogen-secreted host nucleus-infiltrating protein (infiltrin) expressed exclusively by the Schistosoma haematobium egg stage
LF Pennington, A Alouffi, EC Mbanefo, D Ray, DM Heery, TS Jardetzky, ...
Infection and Immunity 85 (12), 10.1128/iai. 00301-17, 2017
362017
Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions
LF Pennington, P Gasser, D Brigger, P Guntern, A Eggel, TS Jardetzky
Journal of Allergy and Clinical Immunology 148 (4), 1049-1060, 2021
252021
The soluble isoform of human Fcɛ RI is an endogenous inhibitor of IgE‐mediated mast cell responses
S Moñino‐Romero, L Erkert, K Schmidthaler, SC Diesner, BF Sallis, ...
Allergy 74 (2), 236-245, 2019
252019
Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis
EC Mbanefo, L Le, LF Pennington, JI Odegaard, TS Jardetzky, A Alouffi, ...
The FASEB Journal 32 (8), 4408, 2018
232018
A new mouse model for female genital schistosomiasis
ML Richardson, CL Fu, LF Pennington, JD Honeycutt, JL Odegaard, ...
PLoS Neglected Tropical Diseases 8 (5), e2825, 2014
172014
IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways
EC Mbanefo, L Le, R Zee, N Banskota, K Ishida, LF Pennington, ...
Scientific Reports 9 (1), 1586, 2019
152019
IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis
EC Mbanefo, CT Agbo, Y Zhao, OK Lamanna, KH Thai, SE Karinshak, ...
Infectious Agents and Cancer 15, 1-10, 2020
132020
Immune response to parasitic infections
LF Pennington, MH Hsieh
Bentham ebooks 2, 93-124, 2014
92014
IPSE, a parasite-derived host immunomodulatory protein, is a potential therapeutic for hemorrhagic cystitis
RS Zee, EC Mbanefo, LH Le, LF Pennington, JI Odegaard, TS Jardetzky, ...
American Journal of Physiology-Renal Physiology 316 (6), F1133-F1140, 2019
82019
Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex
LF Pennington, P Gasser, S Kleinboelting, C Zhang, G Skiniotis, A Eggel, ...
Nature Communications 12 (1), 7069, 2021
62021
SLAP deficiency decreases dsDNA autoantibody production
LK Peterson, LF Pennington, LA Shaw, M Brown, EC Treacy, SF Friend, ...
Clinical Immunology 150 (2), 201-209, 2014
42014
IPSE, a urogenital parasite-derived immunomodulatory molecule, suppresses bladder pathogenesis and anti-microbial peptide gene expression in bacterial urinary tract infection
EC Mbanefo, L Le, LF Pennington, YJ Hsieh, JI Odegaard, K Lapira, ...
Parasites & Vectors 13, 1-11, 2020
32020
Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange. Nat Commun. 2016; 7: 11610
LF Pennington, S Tarchevskaya, D Brigger, K Sathiyamoorthy, ...
3
IPSE, a parasite-derived, host Immunomodulatory Infiltrin protein, alleviates Resiniferatoxin-induced bladder pain
K Ishida, EC Mbanefo, L Le, O Lamanna, LF Pennington, JC Finkel, ...
Molecular Pain 16, 1744806920970099, 2020
22020
Sex-specific differences in immune response to SARS-CoV-2 vaccination vanish with age.
D Brigger, PM Guntern, HR Jonsdottir, LF Pennington, B Weber, ...
Allergy 78 (6), 1683-1686, 2023
12023
Omalizumab resistant IgE variants and their use in anti-IgE therapy
TS Jardetzky, L Pennington
US Patent App. 15/759,188, 2018
12018
The Immunobiology of Urogenital Schistosomiasis
LF Pennington, MH Hsieh
Immunity to Helminths and Novel Therapeutic Approaches 2, 93-124, 2014
12014
The Disruptive Anti-IgE Molecule KIH_E07_79 Rapidly Desensitizes Allergic Effector Cells and Suppresses IgE Production in B-cells
P Guntern, L Pennington, D Brigger, T Jardetzky, A Eggel
Journal of Allergy and Clinical Immunology 153 (2), AB63, 2024
2024
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