Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling G Zimmermann, B Papke, S Ismail, N Vartak, A Chandra, M Hoffmann, ... Nature 497 (7451), 638-642, 2013 | 496 | 2013 |
Drugging RAS: Know the enemy B Papke, CJ Der Science 355 (6330), 1158-1163, 2017 | 188 | 2017 |
KRas localizes to the plasma membrane by spatial cycles of solubilization, trapping and vesicular transport M Schmick, N Vartak, B Papke, M Kovacevic, DC Truxius, L Rossmannek, ... Cell 157 (2), 459-471, 2014 | 176 | 2014 |
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ... Nature medicine 25 (4), 628-640, 2019 | 150 | 2019 |
Identification of pyrazolopyridazinones as PDEδ inhibitors B Papke, S Murarka, HA Vogel, P Martín-Gago, M Kovacevic, DC Truxius, ... Nature communications 7 (1), 1-9, 2016 | 99 | 2016 |
The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins N Vartak, B Papke, HE Grecco, L Rossmannek, H Waldmann, C Hedberg, ... Biophysical journal 106 (1), 93-105, 2014 | 60 | 2014 |
Precise measurement of protein interacting fractions with fluorescence lifetime imaging microscopy KA Walther, B Papke, MB Sinn, K Michel, A Kinkhabwala Molecular Biosystems 7 (2), 322-336, 2011 | 46 | 2011 |
Atypical KRASG12R mutant is impaired in PI3K signaling and macropinocytosis in pancreatic cancer GA Hobbs, NM Baker, AM Miermont, RD Thurman, M Pierobon, TH Tran, ... Cancer discovery 10 (1), 104-123, 2020 | 22 | 2020 |
Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers I Ozkan-Dagliyan, JN Diehl, SD George, A Schaefer, B Papke, ... Cell reports 31 (11), 107764, 2020 | 3 | 2020 |
Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ... Nature medicine, 1-1, 2020 | 1 | 2020 |
The Spatial Organization of Ras Signaling B Papke, M Schmick, N Vartak, PIH Bastiaens Ras Superfamily Small G Proteins: Biology and Mechanisms 1, 173-188, 2014 | 1 | 2014 |
Silencing of oncogenic KRAS by a mutant-favoring short interfering RNA. B Papke, AED Van Swearingen, AY Feng, SH Azam, EB Harrison, R Yang, ... MOLECULAR CANCER RESEARCH 18 (5), 68-69, 2020 | | 2020 |
Abstract B32: Silencing of oncogenic KRAS by a mutant-favoring short interfering RNA B Papke, AED Van Swearingen, AY Feng, SH Azam, EB Harrison, R Yang, ... Molecular Cancer Research 18 (5 Supplement), B32-B32, 2020 | | 2020 |
Silencing of oncogenic KRAS by mutant-selective small interfering RNA B Papke, SH Azam, AY Feng, AED Van Swearingen, C Gutierrez-Ford, ... bioRxiv, 2020 | | 2020 |
Abstract LB-287: Combination therapies with CDK4/6 inhibitors to treat KRAS-mutant pancreatic cancer CM Goodwin, S Javaid, AM Waters, B Papke, R Yang, M Pierobon, ... Cancer Research 79 (13 Supplement), LB-287-LB-287, 2019 | | 2019 |
Therapeutic Silencing of Oncogenic KRAS With a Mutant-Specific Short Interfering RNA: MA27. 06 C Pecot, A Van Swearingen, B Papke Journal of Thoracic Oncology 13 (10), 2018 | | 2018 |
MA27. 06 Therapeutic Silencing of Oncogenic KRAS With a Mutant-Specific Short Interfering RNA C Pecot, A Van Swearingen, B Papke Journal of Thoracic Oncology 13 (10), S456, 2018 | | 2018 |
Pharmacological interference with the PDEδ-K-Ras interaction impairs oncogenic K-Ras signaling B Papke Private Universität Witten/Herdecke Witten, 2014 | | 2014 |
Targeting P130Cas-and Microtubule-Dependent MYC Regulation Sensitizes Pancreatic Cancer to ERK MAPK Inhibition AM Waters, TO Khatib, B Papke, C Goodwin, GA Hobbs, JN Diehl, ... | | |