Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation E Hirsch, VL Katanaev, C Garlanda, O Azzolino, L Pirola, L Silengo, ... Science 287 (5455), 1049-1053, 2000 | 1565 | 2000 |
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response C Garlanda, E Hirsch, S Bozza, A Salustri, M De Acetis, R Nota, ... Nature 420 (6912), 182-186, 2002 | 825 | 2002 |
Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion‐dependent cell survival L Moro, M Venturino, C Bozzo, L Silengo, F Altruda, L Beguinot, G Tarone, ... The EMBO journal, 1998 | 732 | 1998 |
PI3Kγ modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and-independent effects E Patrucco, A Notte, L Barberis, G Selvetella, A Maffei, M Brancaccio, ... Cell 118 (3), 375-387, 2004 | 604 | 2004 |
Hemopexin: structure, function, and regulation E Tolosano, F Altruda DNA and cell biology 21 (4), 297-306, 2002 | 495 | 2002 |
Phosphoinositide 3-kinase γ is an essential amplifier of mast cell function M Laffargue, R Calvez, P Finan, A Trifilieff, M Barbier, F Altruda, E Hirsch, ... Immunity 16 (3), 441-451, 2002 | 391 | 2002 |
Melusin, a muscle-specific integrin β1–interacting protein, is required to prevent cardiac failure in response to chronic pressure overload M Brancaccio, L Fratta, A Notte, E Hirsch, R Poulet, S Guazzone, ... Nature medicine 9 (1), 68-75, 2003 | 358 | 2003 |
Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cells. AM Belkin, NI Zhidkova, F Balzac, F Altruda, D Tomatis, A Maier, G Tarone, ... The Journal of cell biology 132 (1), 211-226, 1996 | 300 | 1996 |
Hemoglobin and heme scavenging P Ascenzi, A Bocedi, P Visca, F Altruda, E Tolosano, T Beringhelli, ... IUBMB life 57 (11), 749-759, 2005 | 296 | 2005 |
Phosphoinositide 3-kinase p110β activity: key role in metabolism and mammary gland cancer but not development E Ciraolo, M Iezzi, R Marone, S Marengo, C Curcio, C Costa, O Azzolino, ... Science signaling 1 (36), ra3-ra3, 2008 | 294 | 2008 |
Resistance to thromboembolism in PI3Kγ‐deficient mice E Hirsch, O Bosco, P Tropel, M Laffargue, R Calvez, F Altruda, ... The FASEB Journal 15 (11), 2019-2021, 2001 | 281 | 2001 |
Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis F Di Cunto, S Imarisio, E Hirsch, V Broccoli, A Bulfone, A Migheli, C Atzori, ... Neuron 28 (1), 115-127, 2000 | 280 | 2000 |
Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK L Barberis, KK Wary, G Fiucci, F Liu, E Hirsch, M Brancaccio, F Altruda, ... Journal of Biological Chemistry 275 (47), 36532-36540, 2000 | 255 | 2000 |
Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases F Vinchi, L De Franceschi, A Ghigo, T Townes, J Cimino, L Silengo, ... Circulation 127 (12), 1317-1329, 2013 | 224 | 2013 |
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ A Perino, A Ghigo, E Ferrero, F Morello, G Santulli, GS Baillie, F Damilano, ... Molecular cell 42 (1), 84-95, 2011 | 219 | 2011 |
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation D Chiabrando, S Marro, S Mercurio, C Giorgi, S Petrillo, F Vinchi, V Fiorito, ... The Journal of clinical investigation 122 (12), 4569-4579, 2012 | 198 | 2012 |
Functional antagonism between Sall4 and Plzf defines germline progenitors RM Hobbs, S Fagoonee, A Papa, K Webster, F Altruda, R Nishinakamura, ... Cell stem cell 10 (3), 284-298, 2012 | 196 | 2012 |
Protection from angiotensin II–mediated vasculotoxic and hypertensive response in mice lacking PI3Kγ C Vecchione, E Patrucco, G Marino, L Barberis, R Poulet, A Aretini, ... The Journal of experimental medicine 201 (8), 1217-1228, 2005 | 195 | 2005 |
Lipids on the move: phosphoinositide 3-kinases in leukocyte function MP Wymann, S Sozzani, F Altruda, A Mantovani, E Hirsch Immunology today 21 (6), 260-264, 2000 | 183 | 2000 |
Phosphoinositide 3-kinase γ: a key modulator in inflammation and allergy MP Wymann, K Björklöf, R Calvez, P Finan, M Thomast, A Trifilieff, ... Biochemical Society Transactions 31 (1), 275-280, 2003 | 182 | 2003 |