Sarah Gillmor Hymowitz
Sarah Gillmor Hymowitz
The Column Group
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Cited by
Cited by
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
AJ Souers, JD Leverson, ER Boghaert, SL Ackler, ND Catron, J Chen, ...
Nature medicine 19 (2), 202-208, 2013
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
W Ouyang, S Rutz, NK Crellin, PA Valdez, SG Hymowitz
Annual review of immunology 29, 71-109, 2011
Therapeutic antibody targeting of individual Notch receptors
Y Wu, C Cain-Hom, L Choy, TJ Hagenbeek, GP De Leon, Y Chen, ...
Nature 464 (7291), 1052-1057, 2010
IL‐17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL‐17F, and implications for receptor binding
SG Hymowitz, EH Filvaroff, JP Yin, J Lee, L Cai, P Risser, M Maruoka, ...
The EMBO journal, 2001
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
KW Wagner, EA Punnoose, T Januario, DA Lawrence, RM Pitti, ...
Nature medicine 13 (9), 1070-1077, 2007
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies
K Newton, ML Matsumoto, IE Wertz, DS Kirkpatrick, JR Lill, J Tan, ...
Cell 134 (4), 668-678, 2008
Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5
SG Hymowitz, HW Christinger, G Fuh, M Ultsch, M O'Connell, RF Kelley, ...
Molecular cell 4 (4), 563-571, 1999
The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity
SA Gillmor, A Villaseņor, R Fletterick, E Sigal, MF Browner
Nature structural biology 4 (12), 1003-1009, 1997
K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody
ML Matsumoto, KE Wickliffe, KC Dong, C Yu, I Bosanac, D Bustos, L Phu, ...
Molecular cell 39 (3), 477-484, 2010
Loss of the tumor suppressor BAP1 causes myeloid transformation
A Dey, D Seshasayee, R Noubade, DM French, J Liu, MS Chaurushiya, ...
Science 337 (6101), 1541-1546, 2012
Specific Btk inhibition suppresses B cell–and myeloid cell–mediated arthritis
JA Di Paolo, T Huang, M Balazs, J Barbosa, KH Barck, BJ Bravo, ...
Nature chemical biology 7 (1), 41-50, 2011
Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors
M Yan, LC Wang, SG Hymowitz, S Schilbach, J Lee, A Goddard, ...
Science 290 (5491), 523-527, 2000
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL
SG Hymowitz, MP O'Connell, MH Ultsch, A Hurst, K Totpal, A Ashkenazi, ...
Biochemistry 39 (4), 633-640, 2000
An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells
NS Wilson, B Yang, A Yang, S Loeser, S Marsters, D Lawrence, Y Li, ...
Cancer cell 19 (1), 101-113, 2011
Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than …
RF Kelley, K Totpal, SH Lindstrom, M Mathieu, K Billeci, L DeForge, R Pai, ...
Journal of Biological Chemistry 280 (3), 2205-2212, 2005
Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity
ZF Tao, L Hasvold, L Wang, X Wang, AM Petros, CH Park, ER Boghaert, ...
ACS medicinal chemistry letters 5 (10), 1088-1093, 2014
A20: from ubiquitin editing to tumour suppression
SG Hymowitz, IE Wertz
Nature Reviews Cancer 10 (5), 332-341, 2010
Molecular recognition by a binary code
FA Fellouse, B Li, DM Compaan, AA Peden, SG Hymowitz, SS Sidhu
Journal of molecular biology 348 (5), 1153-1162, 2005
Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152)
JA Flygare, M Beresini, N Budha, H Chan, IT Chan, S Cheeti, F Cohen, ...
Journal of medicinal chemistry 55 (9), 4101-4113, 2012
Interactions between Hedgehog proteins and their binding partners come into view
PA Beachy, SG Hymowitz, RA Lazarus, DJ Leahy, C Siebold
Genes & development 24 (18), 2001-2012, 2010
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