עקוב אחר
Tomáš Etrych
Tomáš Etrych
Research profesor, Institute of macromolecular chemistry
כתובת אימייל מאומתת בדומיין imc.cas.cz
כותרת
צוטט על ידי
צוטט על ידי
שנה
New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties
T Etrych, M Jelı́nková, B Řı́hová, K Ulbrich
Journal of Controlled Release 73 (1), 89-102, 2001
4282001
In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity
GM Lynn, R Laga, PA Darrah, AS Ishizuka, AJ Balaci, AE Dulcey, ...
Nature biotechnology 33 (11), 1201-1210, 2015
4182015
Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin
M Talelli, M Iman, AK Varkouhi, CJF Rijcken, RM Schiffelers, T Etrych, ...
Biomaterials 31 (30), 7797-7804, 2010
2932010
HPMA copolymers with pH-controlled release of doxorubicin: in vitro cytotoxicity and in vivo antitumor activity
K Ulbrich, T Etrych, P Chytil, M Jelınková, B Řı́hová
Journal of Controlled Release 87 (1-3), 33-47, 2003
2592003
Biodegradable star HPMA polymer–drug conjugates: Biodegradability, distribution and anti-tumor efficacy
T Etrych, L Kovář, J Strohalm, P Chytil, B Říhová, K Ulbrich
Journal of controlled release 154 (3), 241-248, 2011
2002011
New HPMA copolymer-based drug carriers with covalently bound hydrophobic substituents for solid tumour targeting
P Chytil, T Etrych, Č Koňák, M Šírová, T Mrkvan, J Bouček, B Říhová, ...
Journal of Controlled Release 127 (2), 121-130, 2008
1672008
Synthesis of HPMA copolymers containing doxorubicin bound via a hydrazone linkage. Effect of spacer on drug release and in vitro cytotoxicity
T Etrych, P Chytil, M Jelínková, B Říhová, K Ulbrich
Macromolecular bioscience 2 (1), 43-52, 2002
1672002
Antibody-targeted polymer–doxorubicin conjugates with pH-controlled activation
K Ulbrich, T Etrych, P Chytil, M Jelínková, B Říhová
Journal of drug targeting 12 (8), 477-489, 2004
1552004
HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release
T Etrych, M Šírová, L Starovoytova, B Říhová, K Ulbrich
Molecular pharmaceutics 7 (4), 1015-1026, 2010
1522010
Polymer‐coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction
RC Carlisle, T Etrych, SS Briggs, JA Preece, K Ulbrich, LW Seymour
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004
1512004
Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes
L Quan, Y Zhang, BJ Crielaard, A Dusad, SM Lele, CJF Rijcken, ...
ACS nano 8 (1), 458-466, 2014
1502014
Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers
T Lammers, R Kühnlein, M Kissel, V Subr, T Etrych, R Pola, M Pechar, ...
Journal of controlled release 110 (1), 103-118, 2005
1472005
Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy
M Talelli, S Oliveira, CJF Rijcken, EHE Pieters, T Etrych, K Ulbrich, ...
Biomaterials 34 (4), 1255-1260, 2013
1442013
Fluorescence optical imaging in anticancer drug delivery
T Etrych, H Lucas, O Janoušková, P Chytil, T Mueller, K Mäder
Journal of Controlled Release 226, 168-181, 2016
1422016
HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity
T Etrych, V Šubr, J Strohalm, M Šírová, B Říhová, K Ulbrich
Journal of controlled release 164 (3), 346-354, 2012
1422012
N-(2-Hydroxypropyl) methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT …
P Chytil, T Etrych, J Kříž, V Šubr, K Ulbrich
European journal of pharmaceutical sciences 41 (3-4), 473-482, 2010
1422010
Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes
B Rıhová, T Etrych, M Pechar, M Jelınková, M Štastný, O Hovorka, ...
Journal of controlled release 74 (1-3), 225-232, 2001
1392001
Noninvasive optical imaging of nanomedicine biodistribution
S Kunjachan, F Gremse, B Theek, P Koczera, R Pola, M Pechar, T Etrych, ...
ACS nano 7 (1), 252-262, 2013
1342013
N‐(2‐hydroxypropyl)methacrylamide‐based polymer conjugates with pH‐controlled activation of doxorubicin. I. New synthesis, physicochemical characterization …
T Etrych, T Mrkvan, P Chytil, Č Koňák, B Říhová, K Ulbrich
Journal of applied polymer science 109 (5), 3050-3061, 2008
1222008
HPMA-based polymer conjugates with drug combination
H Krakovičová, T Etrych, K Ulbrich
European Journal of Pharmaceutical Sciences 37 (3-4), 405-412, 2009
1182009
המערכת אינה יכולה לבצע את הפעולה כעת. נסה שוב מאוחר יותר.
מאמרים 1–20