Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2 … EA Rozeman, AM Menzies, ACJ van Akkooi, C Adhikari, C Bierman, ... The Lancet Oncology 20 (7), 948-960, 2019 | 459 | 2019 |
Molecular tests for colorectal cancer screening LJW Bosch, B Carvalho, RJA Fijneman, CR Jimenez, HM Pinedo, ... Clinical colorectal cancer 10 (1), 8-23, 2011 | 150 | 2011 |
Consensus molecular subtype classification of colorectal adenomas MA Komor, LJW Bosch, G Bounova, AS Bolijn, PM Delis‐van Diemen, ... The Journal of pathology 246 (3), 266-276, 2018 | 86 | 2018 |
Understanding molecular mechanisms in peritoneal dissemination of colorectal cancer: future possibilities for personalised treatment by use of biomarkers EMV De Cuba, R Kwakman, M Van Egmond, LJW Bosch, HJ Bonjer, ... Virchows Archiv 461, 231-243, 2012 | 82 | 2012 |
Multitarget stool DNA test performance in an average-risk colorectal cancer screening population LJW Bosch, V Melotte, S Mongera, KLJ Daenen, VMH Coupé, ... Official journal of the American College of Gastroenterology| ACG 114 (12 …, 2019 | 78 | 2019 |
Genomic landscape of metastatic colorectal cancer JC Haan, M Labots, C Rausch, M Koopman, J Tol, LJM Mekenkamp, ... Nature communications 5 (1), 5457, 2014 | 75 | 2014 |
Promoter CpG island hypermethylation-and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without … S Derks, LJW Bosch, HEC Niessen, PTM Moerkerk, SM Van Den Bosch, ... Carcinogenesis 30 (6), 1041-1048, 2009 | 72 | 2009 |
DNA methylation of phosphatase and actin regulator 3 detects colorectal cancer in stool and complements FIT LJW Bosch, FA Oort, M Neerincx, CAJ Khalid-de Bakker, JST sive Droste, ... Cancer Prevention Research 5 (3), 464-472, 2012 | 68 | 2012 |
Novel stool-based protein biomarkers for improved colorectal cancer screening: a case–control study LJW Bosch, M De Wit, TV Pham, VMH Coupé, AC Hiemstra, SR Piersma, ... Annals of Internal Medicine 167 (12), 855-866, 2017 | 59 | 2017 |
Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer A Jacobsen, LJW Bosch, SR Martens-de Kemp, B Carvalho, ... Scientific reports 8 (1), 7522, 2018 | 55 | 2018 |
Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers EMV De Cuba, P Snaebjornsson, DAM Heideman, NCT Van Grieken, ... International journal of cancer 138 (5), 1139-1145, 2016 | 55 | 2016 |
Cost-effectiveness of high-performance biomarker tests vs fecal immunochemical test for noninvasive colorectal cancer screening I Lansdorp-Vogelaar, SL Goede, LJW Bosch, V Melotte, B Carvalho, ... Clinical gastroenterology and hepatology 16 (4), 504-512. e11, 2018 | 51 | 2018 |
Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study SJ Schraa, KL Van Rooijen, DEW Van Der Kruijssen, C Rubio Alarcón, ... BMC cancer 20, 1-10, 2020 | 47 | 2020 |
Proteins in stool as biomarkers for non‐invasive detection of colorectal adenomas with high risk of progression MA Komor, LJW Bosch, VMH Coupé, C Rausch, TV Pham, SR Piersma, ... The Journal of pathology 250 (3), 288-298, 2020 | 46 | 2020 |
Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE) KG Samsom, LJW Bosch, LJ Schipper, P Roepman, E de Bruijn, LR Hoes, ... BMC medical genomics 13, 1-7, 2020 | 36 | 2020 |
Fecal tests: From blood to molecular markers GP Young, LJW Bosch Current colorectal cancer reports 7, 62-70, 2011 | 36 | 2011 |
IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma ILM Reijers, D Rao, JM Versluis, AM Menzies, P Dimitriadis, MW Wouters, ... Journal of Experimental Medicine 220 (5), e20221952, 2023 | 34 | 2023 |
Clinical validation of a multitarget fecal immunochemical test for colorectal cancer screening: a diagnostic test accuracy study W de Klaver, PHA Wisse, F van Wifferen, LJW Bosch, CR Jimenez, ... Annals of Internal Medicine 174 (9), 1224-1231, 2021 | 33 | 2021 |
Analytical sensitivity and stability of DNA methylation testing in stool samples for colorectal cancer detection LJW Bosch, S Mongera, JST sive Droste, FA Oort, ST van Turenhout, ... Cellular oncology 35, 309-315, 2012 | 31 | 2012 |
Feasibility of whole‐genome sequencing‐based tumor diagnostics in routine pathology practice KG Samsom, LJ Schipper, P Roepman, LJW Bosch, F Lalezari, ... The Journal of pathology 258 (2), 179-188, 2022 | 27 | 2022 |