An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages JM Silverman, J Clos, CC de'Oliveira, O Shirvani, Y Fang, C Wang, ... Journal of cell science 123 (6), 842-852, 2010 | 562 | 2010 |
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and-independent mechanisms LI Grad, JJ Yerbury, BJ Turner, WC Guest, E Pokrishevsky, MA O’Neill, ... Proceedings of the National Academy of Sciences 111 (9), 3620-3625, 2014 | 472 | 2014 |
Proteomic analysis of the secretome of Leishmania donovani JM Silverman, SK Chan, DP Robinson, DM Dwyer, D Nandan, LJ Foster, ... Genome biology 9, 1-21, 2008 | 381 | 2008 |
Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells JM Silverman, J Clos, E Horakova, AY Wang, M Wiesgigl, I Kelly, MA Lynn, ... The Journal of Immunology 185 (9), 5011-5022, 2010 | 372 | 2010 |
Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles F Martínez-Gutierrez, EP Thi, JM Silverman, CC de Oliveira, SL Svensson, ... Nanomedicine: Nanotechnology, Biology and Medicine 8 (3), 328-336, 2012 | 359 | 2012 |
Exosomes and other microvesicles in infection biology: organelles with unanticipated phenotypes JM Silverman, NE Reiner Cellular microbiology 13 (1), 1-9, 2011 | 252 | 2011 |
Leishmania Exosomes Deliver Preemptive Strikes to Create an Environment Permissive for Early Infection JM Silverman, NE Reiner Frontiers in cellular and infection microbiology 1, 26, 2012 | 164 | 2012 |
CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1) G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1 JM Silverman, D Christy, CC Shyu, KM Moon, S Fernando, Z Gidden, ... Journal of Biological Chemistry 294 (10), 3744-3759, 2019 | 151 | 2019 |
Disease mechanisms in ALS: misfolded SOD1 transferred through exosome-dependent and exosome-independent pathways JM Silverman, SM Fernando, LI Grad, AF Hill, BJ Turner, JJ Yerbury, ... Cellular and molecular neurobiology 36, 377-381, 2016 | 122 | 2016 |
Secreted virulence factors and immune evasion in visceral leishmaniasis U Lambertz, JM Silverman, D Nandan, WR McMaster, J Clos, LJ Foster, ... Journal of leukocyte biology 91 (6), 887-899, 2012 | 102 | 2012 |
Myeloid cell IL-10 production in response to leishmania involves inactivation of glycogen synthase kinase-3β downstream of phosphatidylinositol-3 kinase D Nandan, C Camargo de Oliveira, A Moeenrezakhanlou, M Lopez, ... The Journal of Immunology 188 (1), 367-378, 2012 | 78 | 2012 |
Generalization of the prion hypothesis to other neurodegenerative diseases: an imperfect fit WC Guest, JM Silverman, E Pokrishevsky, MA O'Neill, LI Grad, ... Journal of Toxicology and Environmental Health, Part A 74 (22-24), 1433-1459, 2011 | 77 | 2011 |
Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding LI Grad, E Pokrishevsky, JM Silverman, NR Cashman Prion 8 (5), 331-335, 2014 | 74 | 2014 |
Identification of leishmania fructose-1, 6-bisphosphate aldolase as a novel activator of host macrophage Src homology 2 domain containing protein tyrosine phosphatase SHP-1 D Nandan, T Tran, E Trinh, JM Silverman, M Lopez Biochemical and biophysical research communications 364 (3), 601-607, 2007 | 51 | 2007 |
A rationally designed humanized antibody selective for amyloid beta oligomers in Alzheimer’s disease E Gibbs, JM Silverman, B Zhao, X Peng, J Wang, CL Wellington, ... Scientific reports 9 (1), 9870, 2019 | 44 | 2019 |
Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E J Robert, EB Button, EM Martin, L McAlary, Z Gidden, M Gilmour, G Boyce, ... Molecular neurodegeneration 15, 1-21, 2020 | 34 | 2020 |
A rational structured epitope defines a distinct subclass of toxic amyloid-beta oligomers JM Silverman, E Gibbs, X Peng, KM Martens, C Balducci, J Wang, ... ACS Chemical Neuroscience 9 (7), 1591-1606, 2018 | 26 | 2018 |
P4‐299: A Computational Method to Predict Disease‐Specific Epitopes in Aβ, and its Application to Oligomer‐Selective Antibodies for Alzheimer’S Immunotherapy SS Plotkin, X Peng, JM Silverman, NR Cashman Alzheimer's & Dementia 12, P1148-P1148, 2016 | 10 | 2016 |
Targeting of toxic amyloid-beta oligomer species by monoclonal antibody PMN310: precision drug design for Alzheimer’s disease J Kaplan, JM Silverman, E Gibbs, J Wang, X Peng, SS Plotkin, ... Alzheimer's & Dementia 13 (7), P592, 2017 | 9 | 2017 |
A method for systematically ranking therapeutic drug candidates using multiple uncertain screening criteria X Peng, E Gibbs, JM Silverman, NR Cashman, SS Plotkin Statistical Methods in Medical Research 30 (6), 1502-1522, 2021 | 8 | 2021 |