|An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages|
JM Silverman, J Clos, CC de'Oliveira, O Shirvani, Y Fang, C Wang, ...
Journal of cell science 123 (6), 842-852, 2010
|Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and-independent mechanisms|
LI Grad, JJ Yerbury, BJ Turner, WC Guest, E Pokrishevsky, MA O’Neill, ...
Proceedings of the National Academy of Sciences 111 (9), 3620-3625, 2014
|Proteomic analysis of the secretome of Leishmania donovani|
JM Silverman, SK Chan, DP Robinson, DM Dwyer, D Nandan, LJ Foster, ...
Genome biology 9 (2), 1-21, 2008
|Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles|
F Martínez-Gutierrez, EP Thi, JM Silverman, CC de Oliveira, SL Svensson, ...
Nanomedicine: Nanotechnology, Biology and Medicine 8 (3), 328-336, 2012
|Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells|
JM Silverman, J Clos, E Horakova, AY Wang, M Wiesgigl, I Kelly, MA Lynn, ...
The Journal of Immunology 185 (9), 5011-5022, 2010
|Exosomes and other microvesicles in infection biology: organelles with unanticipated phenotypes|
JM Silverman, NE Reiner
Cellular microbiology 13 (1), 1-9, 2011
|Leishmania exosomes deliver preemptive strikes to create an environment permissive for early infection|
JM Silverman, NE Reiner
Frontiers in cellular and infection microbiology 1, 26, 2012
|Secreted virulence factors and immune evasion in visceral leishmaniasis|
U Lambertz, JM Silverman, D Nandan, WR McMaster, J Clos, LJ Foster, ...
Journal of leukocyte biology 91 (6), 887-899, 2012
|Disease mechanisms in ALS: misfolded SOD1 transferred through exosome-dependent and exosome-independent pathways|
JM Silverman, SM Fernando, LI Grad, AF Hill, BJ Turner, JJ Yerbury, ...
Cellular and molecular neurobiology 36 (3), 377-381, 2016
|Generalization of the prion hypothesis to other neurodegenerative diseases: an imperfect fit|
WC Guest, JM Silverman, E Pokrishevsky, MA O'Neill, LI Grad, ...
Journal of Toxicology and Environmental Health, Part A 74 (22-24), 1433-1459, 2011
|Myeloid cell IL-10 production in response to leishmania involves inactivation of glycogen synthase kinase-3β downstream of phosphatidylinositol-3 kinase|
D Nandan, CC de Oliveira, A Moeenrezakhanlou, M Lopez, JM Silverman, ...
The Journal of Immunology 188 (1), 367-378, 2012
|Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding|
LI Grad, E Pokrishevsky, JM Silverman, NR Cashman
Prion 8 (5), 331-335, 2014
|CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1) G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1|
JM Silverman, D Christy, CC Shyu, KM Moon, S Fernando, Z Gidden, ...
Journal of Biological Chemistry 294 (10), 3744-3759, 2019
|Identification of leishmania fructose-1, 6-bisphosphate aldolase as a novel activator of host macrophage Src homology 2 domain containing protein tyrosine phosphatase SHP-1|
D Nandan, T Tran, E Trinh, JM Silverman, M Lopez
Biochemical and biophysical research communications 364 (3), 601-607, 2007
|A rationally designed humanized antibody selective for amyloid beta oligomers in Alzheimer’s disease|
E Gibbs, JM Silverman, B Zhao, X Peng, J Wang, CL Wellington, ...
Scientific reports 9 (1), 1-14, 2019
|A rational structured epitope defines a distinct subclass of toxic amyloid-beta oligomers|
JM Silverman, E Gibbs, X Peng, KM Martens, C Balducci, J Wang, ...
ACS chemical neuroscience 9 (7), 1591-1606, 2018
|Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E|
J Robert, EB Button, EM Martin, L McAlary, Z Gidden, M Gilmour, G Boyce, ...
Molecular neurodegeneration 15 (1), 1-21, 2020
|[O2–14–03]: TARGETING OF TOXIC AMYLOID‐BETA OLIGOMER SPECIES BY MONOCLONAL ANTIBODY PMN310: PRECISION DRUG DESIGN FOR ALZHEIMER's DISEASE|
J Kaplan, JM Silverman, E Gibbs, J Wang, X Peng, SS Plotkin, ...
Alzheimer's & Dementia 13 (7S_Part_11), P592-P592, 2017
|A COMPUTATIONAL METHOD TO PREDICT DISEASE-SPECIFIC EPITOPES IN Aβ, AND ITS APPLICATION TO OLIGOMER-SELECTIVE ANTIBODIES FOR ALZHEIMER’S IMMUNOTHERAPY|
SS Plotkin, X Peng, JM Silverman, NR Cashman
Alzheimer's & Dementia 7 (12), P1148, 2016
|Achieving the optimal profile for Alzheimer’s immunotherapy: Rational generation of antibodies specific for toxic Aβ oligomers (P6. 084)|
S Plotkin, E Gibbs, X Peng, J Silverman, N Cashman
Neurology 88 (16 Supplement), 2017