| Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system N Strushkevich, F MacKenzie, T Cherkesova, I Grabovec, S Usanov, ... Proceedings of the National Academy of Sciences 108 (25), 10139-10143, 2011 | 308 | 2011 |
| Structural basis of human CYP51 inhibition by antifungal azoles N Strushkevich, SA Usanov, HW Park Journal of molecular biology 397 (4), 1067-1078, 2010 | 305 | 2010 |
| Structural analysis of CYP2R1 in complex with vitamin D3 N Strushkevich, SA Usanov, AN Plotnikov, G Jones, HW Park Journal of molecular biology 380 (1), 95-106, 2008 | 214 | 2008 |
| Structural insights into aldosterone synthase substrate specificity and targeted inhibition N Strushkevich, AA Gilep, L Shen, CH Arrowsmith, AM Edwards, ... Molecular endocrinology 27 (2), 315-324, 2013 | 133 | 2013 |
| Molecular identification of adrenal inner zone antigen as a heme‐binding protein L Min, NV Strushkevich, IN Harnastai, H Iwamoto, AA Gilep, H Takemori, ... The FEBS journal 272 (22), 5832-5843, 2005 | 119 | 2005 |
| Probing the interaction of bovine cytochrome P450scc (CYP11A1) with adrenodoxin: evaluating site-directed mutations by molecular modeling SA Usanov, SE Graham, GI Lepesheva, TN Azeva, NV Strushkevich, ... Biochemistry 41 (26), 8310-8320, 2002 | 81 | 2002 |
| Human steroid and oxysterol 7α‐hydroxylase CYP 7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants AV Yantsevich, YV Dichenko, F MacKenzie, DV Mukha, AV Baranovsky, ... The FEBS journal 281 (6), 1700-1713, 2014 | 41 | 2014 |
| Compound I is the reactive intermediate in the first monooxygenation step during conversion of cholesterol to pregnenolone by cytochrome P450scc: EPR/ENDOR/cryoreduction … R Davydov, AA Gilep, NV Strushkevich, SA Usanov, BM Hoffman Journal of the American Chemical Society 134 (41), 17149-17156, 2012 | 41 | 2012 |
| Structural characterization of human cholesterol 7α-hydroxylase W Tempel, I Grabovec, F MacKenzie, YV Dichenko, SA Usanov, AA Gilep, ... Journal of lipid research 55 (9), 1925-1932, 2014 | 38 | 2014 |
| Conformational dynamics and molecular interaction reactions of recombinant cytochrome P450scc (CYP11A1) detected by fluorescence energy transfer GI Lepesheva, NV Strushkevich, SA Usanov Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1999 | 38 | 1999 |
| Evidence that compound I is the active species in both the hydroxylase and lyase steps by which P450scc converts cholesterol to pregnenolone: EPR/ENDOR/cryoreduction/annealing … R Davydov, N Strushkevich, D Smil, A Yantsevich, A Gilep, S Usanov, ... Biochemistry 54 (48), 7089-7097, 2015 | 36 | 2015 |
| A large-scale comparative analysis of affinity, thermodynamics and functional characteristics of interactions of twelve cytochrome P450 isoforms and their redox partners EO Yablokov, TA Sushko, PV Ershov, AV Florinskaya, OV Gnedenko, ... Biochimie 162, 156-166, 2019 | 23 | 2019 |
| Metabolic fate of human immunoactive sterols in Mycobacterium tuberculosis T Varaksa, S Bukhdruker, I Grabovec, E Marin, A Kavaleuski, A Gusach, ... Journal of molecular biology 433 (4), 166763, 2021 | 22 | 2021 |
| In vitro interactions of abiraterone, erythromycin, and CYP3A4: implications for drug–drug interactions RA Masamrekh, AV Kuzikov, YI Haurychenka, KA Shcherbakov, ... Fundamental & clinical pharmacology 34 (1), 120-130, 2020 | 21 | 2020 |
| Thermodynamics of interactions between mammalian cytochromes P450 and b5 E Yablokov, A Florinskaya, A Medvedev, G Sergeev, N Strushkevich, ... Archives of biochemistry and biophysics 619, 10-15, 2017 | 21 | 2017 |
| Direct molecular fishing of new protein partners for human thromboxane synthase AV Svirid, PV Ershov, EO Yablokov, LA Kaluzhskiy, AV Florinskaya, ... Acta Naturae (англоязычная версия) 9 (4 (34)), 92-100, 2017 | 17 | 2017 |
| Electrochemical oxidation of estrogens as a method for CYP19A1 (aromatase) electrocatalytic activity determination AV Kuzikov, RA Masamrekh, TA Filippova, YI Haurychenka, AA Gilep, ... Electrochimica Acta 333, 135539, 2020 | 16 | 2020 |
| Site-directed mutagenesis of cytochrome P450scc. II. Effect of replacement of the Arg425 and Arg426 residues on the structural and functional properties of the cytochrome P450scc TN Azeva, AA Gilep, GI Lepesheva, NV Strushkevich, SA Usanov Biochemistry (Moscow) 66, 564-575, 2001 | 16 | 2001 |
| Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system EO Yablokov, TA Sushko, LA Kaluzhskiy, AA Kavaleuski, YV Mezentsev, ... The Journal of Steroid Biochemistry and Molecular Biology 208, 105793, 2021 | 15 | 2021 |
| Hydroxylation of antitubercular drug candidate, SQ109, by mycobacterial cytochrome P450 S Bukhdruker, T Varaksa, I Grabovec, E Marin, P Shabunya, M Kadukova, ... International journal of molecular sciences 21 (20), 7683, 2020 | 15 | 2020 |
Sergey A UsanovInstitute of bioorganic chemistry NASBכתובת אימייל מאומתת בדומיין iboch.bas-net.by
