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Philippe P. Roux
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Year
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
M Cargnello, PP Roux
Microbiology and molecular biology reviews 75 (1), 50-83, 2011
37232011
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
PP Roux, J Blenis
Microbiology and molecular biology reviews 68 (2), 320-344, 2004
32812004
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
AR Tee, BD Manning, PP Roux, LC Cantley, J Blenis
Current biology 13 (15), 1259-1268, 2003
15292003
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
AY Choo, SO Yoon, SG Kim, PP Roux, J Blenis
Proceedings of the National Academy of Sciences 105 (45), 17414-17419, 2008
10012008
Neurotrophin signaling through the p75 neurotrophin receptor
PP Roux, PA Barker
Progress in neurobiology 67 (3), 203-233, 2002
9812002
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
PP Roux, BA Ballif, R Anjum, SP Gygi, J Blenis
Proceedings of the National Academy of Sciences 101 (37), 13489-13494, 2004
9762004
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
PP Roux, D Shahbazian, H Vu, MK Holz, MS Cohen, J Taunton, ...
Journal of Biological Chemistry 282 (19), 14056-14064, 2007
8932007
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
D Shahbazian, PP Roux, V Mieulet, MS Cohen, B Raught, J Taunton, ...
The EMBO journal 25 (12), 2781-2791, 2006
6882006
mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling
LA Julien, A Carriere, J Moreau, PP Roux
Molecular and cellular biology 30 (4), 908-921, 2010
5462010
Actin cortex architecture regulates cell surface tension
P Chugh, AG Clark, MB Smith, DAD Cassani, K Dierkes, A Ragab, ...
Nature cell biology 19 (6), 689-697, 2017
4462017
Regulation and function of the RSK family of protein kinases
Y Romeo, X Zhang, PP Roux
Biochemical Journal 441 (2), 553-569, 2012
4302012
Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation
A Carrière, M Cargnello, LA Julien, H Gao, É Bonneil, P Thibault, ...
Current biology 18 (17), 1269-1277, 2008
4232008
NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor–dependent apoptosis
AH Salehi, PP Roux, CJ Kubu, C Zeindler, A Bhakar, LL Tannis, JM Verdi, ...
Neuron 27 (2), 279-288, 2000
4052000
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
WJ Oh, C Wu, SJ Kim, V Facchinetti, LA Julien, M Finlan, PP Roux, B Su, ...
The EMBO journal 29 (23), 3939-3951, 2010
3862010
ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1)
A Carriere, Y Romeo, HA Acosta-Jaquez, J Moreau, E Bonneil, P Thibault, ...
Journal of Biological Chemistry 286 (1), 567-577, 2011
3282011
Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5′ TOP mRNA translation
J Tcherkezian, M Cargnello, Y Romeo, EL Huttlin, G Lavoie, SP Gygi, ...
Genes & development 28 (4), 357-371, 2014
3082014
A comprehensive map of the mTOR signaling network
E Caron, S Ghosh, Y Matsuoka, D Ashton‐Beaucage, M Therrien, ...
Molecular systems biology 6 (1), 453, 2010
2992010
Signaling pathways involved in the regulation of mRNA translation
PP Roux, I Topisirovic
Molecular and cellular biology, 2018
2972018
p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure
PP Roux, MA Colicos, PA Barker, TE Kennedy
Journal of neuroscience 19 (16), 6887-6896, 1999
2961999
Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation
J Tcherkezian, PA Brittis, F Thomas, PP Roux, JG Flanagan
Cell 141 (4), 632-644, 2010
2912010
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Articles 1–20