Philippe P. Roux
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Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
M Cargnello, PP Roux
Microbiology and molecular biology reviews 75 (1), 50-83, 2011
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
PP Roux, J Blenis
Microbiology and molecular biology reviews 68 (2), 320-344, 2004
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
AR Tee, BD Manning, PP Roux, LC Cantley, J Blenis
Current biology 13 (15), 1259-1268, 2003
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
AY Choo, SO Yoon, SG Kim, PP Roux, J Blenis
Proceedings of the National Academy of Sciences 105 (45), 17414-17419, 2008
Neurotrophin signaling through the p75 neurotrophin receptor
PP Roux, PA Barker
Progress in neurobiology 67 (3), 203-233, 2002
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
PP Roux, BA Ballif, R Anjum, SP Gygi, J Blenis
Proceedings of the National Academy of Sciences 101 (37), 13489-13494, 2004
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
PP Roux, D Shahbazian, H Vu, MK Holz, MS Cohen, J Taunton, ...
Journal of Biological Chemistry 282 (19), 14056-14064, 2007
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
D Shahbazian, PP Roux, V Mieulet, MS Cohen, B Raught, J Taunton, ...
The EMBO journal 25 (12), 2781-2791, 2006
mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling
LA Julien, A Carriere, J Moreau, PP Roux
Molecular and cellular biology 30 (4), 908-921, 2010
Actin cortex architecture regulates cell surface tension
P Chugh, AG Clark, MB Smith, DAD Cassani, K Dierkes, A Ragab, ...
Nature cell biology 19 (6), 689-697, 2017
Regulation and function of the RSK family of protein kinases
Y Romeo, X Zhang, PP Roux
Biochemical Journal 441 (2), 553-569, 2012
Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation
A Carrière, M Cargnello, LA Julien, H Gao, É Bonneil, P Thibault, ...
Current biology 18 (17), 1269-1277, 2008
NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor–dependent apoptosis
AH Salehi, PP Roux, CJ Kubu, C Zeindler, A Bhakar, LL Tannis, JM Verdi, ...
Neuron 27 (2), 279-288, 2000
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
WJ Oh, C Wu, SJ Kim, V Facchinetti, LA Julien, M Finlan, PP Roux, B Su, ...
The EMBO journal 29 (23), 3939-3951, 2010
ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1)
A Carriere, Y Romeo, HA Acosta-Jaquez, J Moreau, E Bonneil, P Thibault, ...
Journal of Biological Chemistry 286 (1), 567-577, 2011
Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5′ TOP mRNA translation
J Tcherkezian, M Cargnello, Y Romeo, EL Huttlin, G Lavoie, SP Gygi, ...
Genes & development 28 (4), 357-371, 2014
A comprehensive map of the mTOR signaling network
E Caron, S Ghosh, Y Matsuoka, D Ashton‐Beaucage, M Therrien, ...
Molecular systems biology 6 (1), 453, 2010
Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation
J Tcherkezian, PA Brittis, F Thomas, PP Roux, JG Flanagan
Cell 141 (4), 632-644, 2010
p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure
PP Roux, MA Colicos, PA Barker, TE Kennedy
Journal of neuroscience 19 (16), 6887-6896, 1999
Signaling pathways involved in the regulation of mRNA translation
PP Roux, I Topisirovic
Molecular and cellular biology, 2018
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