Christopher D Brown
Christopher D Brown
Associate Professor of Genetics, University of Pennsylvania
Verified email at - Homepage
Cited by
Cited by
Genetic effects on gene expression across human tissues
GTE Consortium
Nature 550 (7675), 204, 2017
Identification of functional elements and regulatory circuits by Drosophila modENCODE
S Roy, J Ernst, PV Kharchenko, P Kheradpour, N Negre, ML Eaton, ...
Science 330 (6012), 1787-1797, 2010
Unlocking the secrets of the genome
SE Celniker, LAL Dillon, MB Gerstein, KC Gunsalus, S Henikoff, ...
Nature 459 (7249), 927-930, 2009
A cis-regulatory map of the Drosophila genome
N Nègre, CD Brown, L Ma, CA Bristow, SW Miller, U Wagner, ...
Nature 471 (7339), 527-531, 2011
Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas
TY Seiwert, Z Zuo, MK Keck, A Khattri, CS Pedamallu, T Stricker, C Brown, ...
Clinical cancer research 21 (3), 632-641, 2015
A comprehensive map of insulator elements for the Drosophila genome
N Nègre, CD Brown, PK Shah, P Kheradpour, CA Morrison, JG Henikoff, ...
PLoS genetics 6 (1), e1000814, 2010
Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes
MK Keck, Z Zuo, A Khattri, TP Stricker, CD Brown, M Imanguli, D Rieke, ...
Clinical cancer research 21 (4), 870-881, 2015
Dynamic landscape and regulation of RNA editing in mammals
MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ...
Nature 550 (7675), 249-254, 2017
The GTEx Consortium atlas of genetic regulatory effects across human tissues
GTEx Consortium
Science 369 (6509), 1318-1330, 2020
Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue
F Innocenti, GM Cooper, IB Stanaway, ER Gamazon, JD Smith, S Mirkov, ...
PLoS Genetics 7 (5), e1002078, 2011
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy
LM Mangravite, BE Engelhardt, MW Medina, JD Smith, CD Brown, ...
Nature 502 (7471), 377-380, 2013
Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs
CD Brown, LM Mangravite, BE Engelhardt
PLoS Genet 9 (8), e1003649, 2013
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data
Y Tao, J Ruan, SH Yeh, X Lu, Y Wang, W Zhai, J Cai, S Ling, Q Gong, ...
Proceedings of the National Academy of Sciences 108 (29), 12042, 2011
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
ME McNerney, CD Brown, X Wang, ET Bartom, S Karmakar, ...
Blood, 2012
Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer
J Liu, M Ghanim, L Xue, CD Brown, I Iossifov, C Angeletti, S Hua, N Nègre, ...
Science 323 (5918), 1218-1222, 2009
Functional architecture and evolution of transcriptional elements that drive gene coexpression
CD Brown, DS Johnson, A Sidow
Science 317 (5844), 1557, 2007
Transposable elements are the primary source of novelty in primate gene regulation
M Trizzino, YS Park, M Holsbach-Beltrame, K Aracena, K Mika, ...
Genome research 27 (10), 1623-1633, 2017
Co-expression networks reveal the tissue-specific regulation of transcription and splicing
A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ...
Genome research 27 (11), 1843-1858, 2017
Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis.
LC Doré, TM Chlon, CD Brown, KP White, JD Crispino
Blood, 2012
Large, diverse population cohorts of hiPSCs and derived hepatocyte-like cells reveal functional genetic variation at blood lipid-associated loci
EE Pashos, Y Park, X Wang, A Raghavan, W Yang, D Abbey, DT Peters, ...
Cell stem cell 20 (4), 558-570. e10, 2017
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