Christopher D Brown
Christopher D Brown
Associate Professor of Genetics, University of Pennsylvania
Verified email at pennmedicine.upenn.edu - Homepage
Title
Cited by
Cited by
Year
Genetic effects on gene expression across human tissues
GTE Consortium
Nature 550 (7675), 204, 2017
14482017
Identification of functional elements and regulatory circuits by Drosophila modENCODE
S Roy, J Ernst, PV Kharchenko, P Kheradpour, N Negre, ML Eaton, ...
Science 330 (6012), 1787-1797, 2010
8972010
Unlocking the secrets of the genome
SE Celniker, LAL Dillon, MB Gerstein, KC Gunsalus, S Henikoff, ...
Nature 459 (7249), 927-930, 2009
8522009
A cis-regulatory map of the Drosophila genome
N Nègre, CD Brown, L Ma, CA Bristow, SW Miller, U Wagner, ...
Nature 471 (7339), 527-531, 2011
4882011
Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas
TY Seiwert, Z Zuo, MK Keck, A Khattri, CS Pedamallu, T Stricker, C Brown, ...
Clinical cancer research 21 (3), 632-641, 2015
4502015
A comprehensive map of insulator elements for the Drosophila genome
N Nègre, CD Brown, PK Shah, P Kheradpour, CA Morrison, JG Henikoff, ...
PLoS genetics 6 (1), e1000814, 2010
3082010
Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes
MK Keck, Z Zuo, A Khattri, TP Stricker, CD Brown, M Imanguli, D Rieke, ...
Clinical cancer research 21 (4), 870-881, 2015
2622015
Dynamic landscape and regulation of RNA editing in mammals
MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ...
Nature 550 (7675), 249-254, 2017
2572017
The GTEx Consortium atlas of genetic regulatory effects across human tissues
GTEx Consortium
Science 369 (6509), 1318-1330, 2020
2562020
Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue
F Innocenti, GM Cooper, IB Stanaway, ER Gamazon, JD Smith, S Mirkov, ...
PLoS Genetics 7 (5), e1002078, 2011
2382011
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy
LM Mangravite, BE Engelhardt, MW Medina, JD Smith, CD Brown, ...
Nature 502 (7471), 377-380, 2013
1962013
Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs
CD Brown, LM Mangravite, BE Engelhardt
PLoS Genet 9 (8), e1003649, 2013
1622013
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data
Y Tao, J Ruan, SH Yeh, X Lu, Y Wang, W Zhai, J Cai, S Ling, Q Gong, ...
Proceedings of the National Academy of Sciences 108 (29), 12042, 2011
1482011
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
ME McNerney, CD Brown, X Wang, ET Bartom, S Karmakar, ...
Blood, 2012
1342012
Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer
J Liu, M Ghanim, L Xue, CD Brown, I Iossifov, C Angeletti, S Hua, N Nègre, ...
Science 323 (5918), 1218-1222, 2009
1302009
Functional architecture and evolution of transcriptional elements that drive gene coexpression
CD Brown, DS Johnson, A Sidow
Science 317 (5844), 1557, 2007
1282007
Transposable elements are the primary source of novelty in primate gene regulation
M Trizzino, YS Park, M Holsbach-Beltrame, K Aracena, K Mika, ...
Genome research 27 (10), 1623-1633, 2017
1162017
Co-expression networks reveal the tissue-specific regulation of transcription and splicing
A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ...
Genome research 27 (11), 1843-1858, 2017
1072017
Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis.
LC Doré, TM Chlon, CD Brown, KP White, JD Crispino
Blood, 2012
1042012
Large, diverse population cohorts of hiPSCs and derived hepatocyte-like cells reveal functional genetic variation at blood lipid-associated loci
EE Pashos, Y Park, X Wang, A Raghavan, W Yang, D Abbey, DT Peters, ...
Cell stem cell 20 (4), 558-570. e10, 2017
932017
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