Deep biomarkers of human aging: application of deep neural networks to biomarker development E Putin, P Mamoshina, A Aliper, M Korzinkin, A Moskalev, A Kolosov, ... Aging (Albany NY) 8 (5), 1021, 2016 | 360 | 2016 |
Oncofinder, a new method for the analysis of intracellular signaling pathway activation using transcriptomic data AA Buzdin, AA Zhavoronkov, MB Korzinkin, LS Venkova, AA Zenin, ... Frontiers in genetics 5, 78170, 2014 | 97 | 2014 |
AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor F Ren, X Ding, M Zheng, M Korzinkin, X Cai, W Zhu, A Mantsyzov, ... Chemical Science 14 (6), 1443-1452, 2023 | 92 | 2023 |
Signaling pathways activation profiles make better markers of cancer than expression of individual genes NM Borisov, NV Terekhanova, AM Aliper, LS Venkova, PY Smirnov, ... Oncotarget 5 (20), 10198, 2014 | 78 | 2014 |
Immune profiles in primary squamous cell carcinoma of the head and neck V Saloura, E Izumchenko, Z Zuo, R Bao, M Korzinkin, I Ozerov, ... Oral Oncology 96, 77-88, 2019 | 67 | 2019 |
The OncoFinder algorithm for minimizing the errors introduced by the high-throughput methods of transcriptome analysis AA Buzdin, AA Zhavoronkov, MB Korzinkin, SA Roumiantsev, AM Aliper, ... Frontiers in molecular biosciences 1, 8, 2014 | 60 | 2014 |
A method for predicting target drug efficiency in cancer based on the analysis of signaling pathway activation A Artemov, A Aliper, M Korzinkin, K Lezhnina, L Jellen, N Zhukov, ... Oncotarget 6 (30), 29347, 2015 | 58 | 2015 |
Data aggregation at the level of molecular pathways improves stability of experimental transcriptomic and proteomic data N Borisov, M Suntsova, M Sorokin, A Garazha, O Kovalchuk, A Aliper, ... Cell cycle 16 (19), 1810-1823, 2017 | 49 | 2017 |
Novel robust biomarkers for human bladder cancer based on activation of intracellular signaling pathways K Lezhnina, O Kovalchuk, AA Zhavoronkov, MB Korzinkin, ... Oncotarget 5 (19), 9022, 2014 | 48 | 2014 |
Use of deep neural network ensembles to identify embryonic-fetal transition markers: repression of COX7A1 in embryonic and cancer cells MD West, I Labat, H Sternberg, D Larocca, I Nasonkin, KB Chapman, ... Oncotarget 9 (8), 7796, 2018 | 41 | 2018 |
Molecular pathway activation features linked with transition from normal skin to primary and metastatic melanomas in human D Shepelin, M Korzinkin, A Vanyushina, A Aliper, N Borisov, R Vasilov, ... Oncotarget 7 (1), 656, 2016 | 36 | 2016 |
Mathematical justification of expression-based pathway activation scoring (PAS) AM Aliper, MB Korzinkin, NB Kuzmina, AA Zenin, LS Venkova, ... Biological Networks and Pathway Analysis, 31-51, 2017 | 26 | 2017 |
MiRImpact, a new bioinformatic method using complete microRNA expression profiles to assess their overall influence on the activity of intracellular molecular pathways AV Artcibasova, MB Korzinkin, MI Sorokin, PV Shegay, AA Zhavoronkov, ... Cell Cycle 15 (5), 689-698, 2016 | 24 | 2016 |
Radioprotectors. org: an open database of known and predicted radioprotectors AM Aliper, ME Bozdaganyan, VA Sarkisova, AP Veviorsky, IV Ozerov, ... Aging (Albany NY) 12 (15), 15741, 2020 | 19 | 2020 |
Doublecortin-like kinase 1 (DCLK1) is a novel NOTCH pathway signaling regulator in head and neck squamous cell carcinoma EC Broner, JA Trujillo, M Korzinkin, T Subbannayya, N Agrawal, ... Frontiers in Oncology 11, 677051, 2021 | 17 | 2021 |
Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma JL Chao, M Korzinkin, A Zhavoronkov, IV Ozerov, MT Walker, K Higgins, ... Cell Reports Medicine 2 (9), 2021 | 13 | 2021 |
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization M Berquez, Z Chen, BP Festa, P Krohn, SA Keller, S Parolo, M Korzinkin, ... Nature Communications 14 (1), 3994, 2023 | 12 | 2023 |
PIM1 kinase promotes gallbladder cancer cell proliferation via inhibition of proline-rich Akt substrate of 40 kDa (PRAS40) T Subbannayya, P Leal-Rojas, A Zhavoronkov, IV Ozerov, M Korzinkin, ... Journal of Cell Communication and Signaling 13, 163-177, 2019 | 12 | 2019 |
Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics-an AI-enabled biological target discovery platform A Olsen, Z Harpaz, C Ren, A Shneyderman, A Veviorskiy, M Dralkina, ... Aging (Albany NY) 15 (8), 2863, 2023 | 3 | 2023 |
System, Method and Software for Predicting Drug Efficacy in a Patient A Zhavoronkov, K Lezhnina, M Korzinkin, D Shepelin, A Artemov, A Aliper, ... US Patent App. 15/008,465, 2016 | 1 | 2016 |