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john bringas
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Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach
KS Bankiewicz, JL Eberling, M Kohutnicka, W Jagust, P Pivirotto, ...
Experimental neurology 164 (1), 2-14, 2000
4782000
A review of brain retraction and recommendations for minimizing intraoperative brain injury
RJ Andrews, JR Bringas
Neurosurgery 33 (6), 1052-1064, 1993
3731993
Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging
R Saito, JR Bringas, TR McKnight, MF Wendland, C Mamot, ...
Cancer research 64 (7), 2572-2579, 2004
3362004
Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates
L Samaranch, EA Salegio, W San Sebastian, AP Kells, KD Foust, ...
Human gene therapy 23 (4), 382-389, 2012
3302012
Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC
KS Bankiewicz, J Forsayeth, JL Eberling, R Sanchez-Pernaute, P Pivirotto, ...
Molecular Therapy 14 (4), 564-570, 2006
3162006
Reflux-free cannula for convection-enhanced high-speed delivery of therapeutic agents
MT Krauze, R Saito, C Noble, M Tamas, J Bringas, JW Park, MS Berger, ...
Journal of neurosurgery 103 (5), 923-929, 2005
2602005
Eight years of clinical improvement in MPTP-lesioned primates after gene therapy with AAV2-hAADC
P Hadaczek, JL Eberling, P Pivirotto, J Bringas, J Forsayeth, ...
Molecular Therapy 18 (8), 1458-1461, 2010
1852010
Extensive distribution of liposomes in rodent brains and brain tumors following convection-enhanced delivery
C Mamot, JB Nguyen, M Pourdehnad, P Hadaczek, R Saito, JR Bringas, ...
Journal of neuro-oncology 68, 1-9, 2004
1822004
Gadolinium-loaded liposomes allow for real-time magnetic resonance imaging of convection-enhanced delivery in the primate brain
R Saito, MT Krauze, JR Bringas, C Noble, TR McKnight, P Jackson, ...
Experimental neurology 196 (2), 381-389, 2005
1722005
Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates
L Samaranch, EA Salegio, W San Sebastian, AP Kells, JR Bringas, ...
Human gene therapy 24 (5), 526-532, 2013
1632013
Efficient gene therapy-based method for the delivery of therapeutics to primate cortex
AP Kells, P Hadaczek, D Yin, J Bringas, V Varenika, J Forsayeth, ...
Proceedings of the National Academy of Sciences 106 (7), 2407-2411, 2009
1622009
AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction
L Samaranch, W San Sebastian, AP Kells, EA Salegio, G Heller, ...
Molecular Therapy 22 (2), 329-337, 2014
1602014
Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial …
R Saito, JR Bringas, A Panner, M Tamas, RO Pieper, MS Berger, ...
Cancer research 64 (19), 6858-6862, 2004
1492004
Convection-enhanced delivery of adeno-associated virus type 2 (AAV2) into the striatum and transport of AAV2 within monkey brain
P Hadaczek, M Kohutnicka, MT Krauze, J Bringas, P Pivirotto, ...
Human gene therapy 17 (3), 291-302, 2006
1392006
Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF
AP Kells, J Eberling, X Su, P Pivirotto, J Bringas, P Hadaczek, WC Narrow, ...
Journal of Neuroscience 30 (28), 9567-9577, 2010
1332010
Canine spontaneous glioma: a translational model system for convection-enhanced delivery
PJ Dickinson, RA LeCouteur, RJ Higgins, JR Bringas, RF Larson, ...
Neuro-oncology 12 (9), 928-940, 2010
1312010
Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys
X Su, AP Kells, EJ Huang, HS Lee, P Hadaczek, J Beyer, J Bringas, ...
Human gene therapy 20 (12), 1627-1640, 2009
1182009
A dose-ranging study of AAV-hAADC therapy in Parkinsonian monkeys
JR Forsayeth, JL Eberling, LM Sanftner, Z Zhen, P Pivirotto, J Bringas, ...
Molecular Therapy 14 (4), 571-577, 2006
1172006
Canine model of convection-enhanced delivery of liposomes containing CPT-11 monitored with real-time magnetic resonance imaging
PJ Dickinson, RA LeCouteur, RJ Higgins, JR Bringas, B Roberts, ...
Journal of neurosurgery 108 (5), 989-998, 2008
1122008
Real-time MR imaging of adeno-associated viral vector delivery to the primate brain
MS Fiandaca, V Varenika, J Eberling, T McKnight, J Bringas, P Pivirotto, ...
Neuroimage 47, T27-T35, 2009
1112009
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