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Raphael I. Benhamou
Raphael I. Benhamou
Verified email at mail.huji.ac.il
Title
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Cited by
Year
Targeting the SARS-CoV-2 RNA genome with small molecule binders and ribonuclease targeting chimera (RIBOTAC) degraders
HS Haniff, Y Tong, X Liu, JL Chen, BM Suresh, RJ Andrews, JM Peterson, ...
ACS Central Science 6 (10), 1713-1721, 2020
1642020
Bacterial-derived exopolysaccharides enhance antifungal drug tolerance in a cross-kingdom oral biofilm
D Kim, Y Liu, RI Benhamou, H Sanchez, Á Simón-Soro, Y Li, G Hwang, ...
The ISME Journal 12 (6), 1427-1442, 2018
1282018
Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus
D Matzov, Z Eyal, RI Benhamou, M Shalev-Benami, Y Halfon, M Krupkin, ...
Nucleic acids research 45 (17), 10284-10292, 2017
682017
Real-time imaging of the azole class of antifungal drugs in live Candida cells
RI Benhamou, M Bibi, KB Steinbuch, H Engel, M Levin, Y Roichman, ...
ACS chemical biology 12 (7), 1769-1777, 2017
682017
Reprogramming of protein-targeted small-molecule medicines to RNA by ribonuclease recruitment
P Zhang, X Liu, D Abegg, T Tanaka, Y Tong, RI Benhamou, J Baisden, ...
Journal of the American Chemical Society 143 (33), 13044-13055, 2021
642021
Antifungal activity, mode of action variability, and subcellular distribution of coumarin-based antifungal azoles
R Elias, RI Benhamou, QZ Jaber, O Dorot, SL Zada, K Oved, E Pichinuk, ...
European journal of medicinal chemistry 179, 779-790, 2019
582019
Di‐N‐Methylation of Anti‐Gram‐Positive Aminoglycoside‐Derived Membrane Disruptors Improves Antimicrobial Potency and Broadens Spectrum to Gram …
RI Benhamou, P Shaul, IM Herzog, M Fridman
Angewandte Chemie 127 (46), 13821-13825, 2015
532015
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models
JA Bush, H Aikawa, R Fuerst, Y Li, A Ursu, SM Meyer, RI Benhamou, ...
Science translational medicine 13 (617), eabd5991, 2021
482021
Tobramycin and nebramine as pseudo‐oligosaccharide scaffolds for the development of antimicrobial cationic amphiphiles
Y Berkov‐Zrihen, IM Herzog, RI Benhamou, M Feldman, KB Steinbuch, ...
Chemistry–A European Journal 21 (11), 4340-4349, 2015
412015
Programming inactive RNA-binding small molecules into bioactive degraders
Y Tong, Y Lee, X Liu, JL Childs-Disney, BM Suresh, RI Benhamou, ...
Nature 618 (7963), 169-179, 2023
402023
Localizing Antifungal Drugs to the Correct Organelle can Markedly Enhance their Efficacy
RI Benhamou, M Bibi, J Berman, M Fridman
Angewandte Chemie, 2018
372018
DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor
RI Benhamou, BM Suresh, Y Tong, WG Cochrane, V Cavett, ...
Proceedings of the National Academy of Sciences 119 (6), e2114971119, 2022
332022
Increased degree of unsaturation in the lipid of antifungal cationic amphiphiles facilitates selective fungal cell disruption
KB Steinbuch, RI Benhamou, L Levin, R Stein, M Fridman
ACS Infectious Diseases 4 (5), 825-836, 2018
332018
Fluorescent tracking of the endoplasmic reticulum in live pathogenic fungal cells
RI Benhamou, QZ Jaber, IM Herzog, Y Roichman, M Fridman
ACS Chemical Biology 13 (12), 3325-3332, 2018
302018
A small molecule that binds an RNA repeat expansion stimulates its decay via the exosome complex
AJ Angelbello, RI Benhamou, SG Rzuczek, S Choudhary, Z Tang, ...
Cell chemical biology 28 (1), 34-45. e6, 2021
282021
Combining colistin and fluconazole synergistically increases fungal membrane permeability and antifungal cidality
M Bibi, S Murphy, RI Benhamou, A Rosenberg, A Ulman, T Bicanic, ...
ACS Infectious Diseases 7 (2), 377-389, 2021
242021
Structure-specific cleavage of an RNA repeat expansion with a dimeric small molecule is advantageous over sequence-specific recognition by an oligonucleotide
RI Benhamou, AJ Angelbello, RJ Andrews, ET Wang, WN Moss, ...
ACS chemical biology 15 (2), 485-493, 2020
242020
Cationic amphiphiles induce macromolecule denaturation and organelle decomposition in pathogenic yeast
QZ Jaber, RI Benhamou, IM Herzog, B Ben Baruch, M Fridman
Angewandte Chemie 130 (50), 16629-16633, 2018
242018
Antifungal Imidazole‐Decorated Cationic Amphiphiles with Markedly Low Hemolytic Activity
RI Benhamou, KB Steinbuch, M Fridman
Chemistry–A European Journal 22 (32), 11148-11151, 2016
222016
Tuning the Effects of Bacterial Membrane Permeability through Photo‐Isomerization of Antimicrobial Cationic Amphiphiles
J Salta, RI Benhamou, IM Herzog, M Fridman
Chemistry a European Journal 23 (52), 12724-12728, 2017
212017
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