| Targeting the SARS-CoV-2 RNA genome with small molecule binders and ribonuclease targeting chimera (RIBOTAC) degraders HS Haniff, Y Tong, X Liu, JL Chen, BM Suresh, RJ Andrews, JM Peterson, ... ACS Central Science 6 (10), 1713-1721, 2020 | 147 | 2020 |
| Bacterial-derived exopolysaccharides enhance antifungal drug tolerance in a cross-kingdom oral biofilm D Kim, Y Liu, RI Benhamou, H Sanchez, Á Simón-Soro, Y Li, G Hwang, ... The ISME journal 12 (6), 1427-1442, 2018 | 125 | 2018 |
| Real-time imaging of the azole class of antifungal drugs in live Candida cells RI Benhamou, M Bibi, KB Steinbuch, H Engel, M Levin, Y Roichman, ... ACS chemical biology 12 (7), 1769-1777, 2017 | 68 | 2017 |
| Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus D Matzov, Z Eyal, RI Benhamou, M Shalev-Benami, Y Halfon, M Krupkin, ... Nucleic acids research 45 (17), 10284-10292, 2017 | 67 | 2017 |
| Reprogramming of protein-targeted small-molecule medicines to RNA by ribonuclease recruitment P Zhang, X Liu, D Abegg, T Tanaka, Y Tong, RI Benhamou, J Baisden, ... Journal of the American Chemical Society 143 (33), 13044-13055, 2021 | 58 | 2021 |
| Antifungal activity, mode of action variability, and subcellular distribution of coumarin-based antifungal azoles R Elias, RI Benhamou, QZ Jaber, O Dorot, SL Zada, K Oved, E Pichinuk, ... European journal of medicinal chemistry 179, 779-790, 2019 | 57 | 2019 |
| Di‐N‐Methylation of Anti‐Gram‐Positive Aminoglycoside‐Derived Membrane Disruptors Improves Antimicrobial Potency and Broadens Spectrum to Gram … RI Benhamou, P Shaul, IM Herzog, M Fridman Angewandte Chemie 127 (46), 13821-13825, 2015 | 53 | 2015 |
| Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models JA Bush, H Aikawa, R Fuerst, Y Li, A Ursu, SM Meyer, RI Benhamou, ... Science translational medicine 13 (617), eabd5991, 2021 | 41 | 2021 |
| Tobramycin and nebramine as pseudo‐oligosaccharide scaffolds for the development of antimicrobial cationic amphiphiles Y Berkov‐Zrihen, IM Herzog, RI Benhamou, M Feldman, KB Steinbuch, ... Chemistry–A European Journal 21 (11), 4340-4349, 2015 | 40 | 2015 |
| Localizing Antifungal Drugs to the Correct Organelle can Markedly Enhance their Efficacy RI Benhamou, M Bibi, J Berman, M Fridman Angewandte Chemie, 2018 | 37 | 2018 |
| Increased degree of unsaturation in the lipid of antifungal cationic amphiphiles facilitates selective fungal cell disruption KB Steinbuch, RI Benhamou, L Levin, R Stein, M Fridman ACS Infectious Diseases 4 (5), 825-836, 2018 | 33 | 2018 |
| Fluorescent tracking of the endoplasmic reticulum in live pathogenic fungal cells RI Benhamou, QZ Jaber, IM Herzog, Y Roichman, M Fridman ACS Chemical Biology 13 (12), 3325-3332, 2018 | 31 | 2018 |
| Programming inactive RNA-binding small molecules into bioactive degraders Y Tong, Y Lee, X Liu, JL Childs-Disney, BM Suresh, RI Benhamou, ... Nature 618 (7963), 169-179, 2023 | 28 | 2023 |
| DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor RI Benhamou, BM Suresh, Y Tong, WG Cochrane, V Cavett, ... Proceedings of the National Academy of Sciences 119 (6), e2114971119, 2022 | 27 | 2022 |
| A small molecule that binds an RNA repeat expansion stimulates its decay via the exosome complex AJ Angelbello, RI Benhamou, SG Rzuczek, S Choudhary, Z Tang, ... Cell chemical biology 28 (1), 34-45. e6, 2021 | 25 | 2021 |
| Cationic amphiphiles induce macromolecule denaturation and organelle decomposition in pathogenic yeast QZ Jaber, RI Benhamou, IM Herzog, B Ben Baruch, M Fridman Angewandte Chemie 130 (50), 16629-16633, 2018 | 24 | 2018 |
| Antifungal Imidazole‐Decorated Cationic Amphiphiles with Markedly Low Hemolytic Activity RI Benhamou, KB Steinbuch, M Fridman Chemistry–A European Journal 22 (32), 11148-11151, 2016 | 22 | 2016 |
| Structure-specific cleavage of an RNA repeat expansion with a dimeric small molecule is advantageous over sequence-specific recognition by an oligonucleotide RI Benhamou, AJ Angelbello, RJ Andrews, ET Wang, WN Moss, ... ACS chemical biology 15 (2), 485-493, 2020 | 21 | 2020 |
| Tuning the Effects of Bacterial Membrane Permeability through Photo‐Isomerization of Antimicrobial Cationic Amphiphiles J Salta, RI Benhamou, IM Herzog, M Fridman Chemistry a European Journal 23 (52), 12724-12728, 2017 | 21 | 2017 |
| Combining colistin and fluconazole synergistically increases fungal membrane permeability and antifungal cidality M Bibi, S Murphy, RI Benhamou, A Rosenberg, A Ulman, T Bicanic, ... ACS Infectious Diseases 7 (2), 377-389, 2021 | 20 | 2021 |
