Genevieve Van de Bittner
Genevieve Van de Bittner
Harvard Medical School, Massachusetts General Hospital
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Boronate oxidation as a bioorthogonal reaction approach for studying the chemistry of hydrogen peroxide in living systems
AR Lippert, GC Van de Bittner, CJ Chang
Accounts of chemical research 44 (9), 793-804, 2011
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
GC Van de Bittner, EA Dubikovskaya, CR Bertozzi, CJ Chang
Proceedings of the National Academy of Sciences 107 (50), 21316-21321, 2010
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
GC Van de Bittner, CR Bertozzi, CJ Chang
Journal of the American Chemical Society 135 (5), 1783-1795, 2013
Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model
T Hirayama, GC Van de Bittner, LW Gray, S Lutsenko, CJ Chang
Proceedings of the National Academy of Sciences 109 (7), 2228-2233, 2012
In vivo bioluminescence imaging reveals copper deficiency in a murine model of nonalcoholic fatty liver disease
MC Heffern, HM Park, HY Au-Yeung, GC Van de Bittner, CM Ackerman, ...
Proceedings of the National Academy of Sciences 113 (50), 14219-14224, 2016
A philosophy for CNS radiotracer design
GC Van de Bittner, EL Ricq, JM Hooker
Accounts of chemical research 47 (10), 3127-3134, 2014
A novel radiotracer for imaging monoacylglycerol lipase in the brain using positron emission tomography
C Wang, MS Placzek, GC Van de Bittner, FA Schroeder, JM Hooker
ACS chemical neuroscience 7 (4), 484-489, 2016
PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat
FA Schroeder, C Wang, GC Van de Bittner, R Neelamegam, ...
ACS chemical neuroscience 5 (10), 1055-1062, 2014
Functionally biased D2R antagonists: targeting the β-arrestin pathway to improve antipsychotic treatment
M We´wer, Q Xu, JP Gale, M Lewis, AJ Campbell, FA Schroeder, ...
ACS chemical biology 13 (4), 1038-1047, 2018
Development of a fluorinated class-I HDAC radiotracer reveals key chemical determinants of brain penetrance
MG Strebl, C Wang, FA Schroeder, MS Placzek, HY Wey, ...
ACS chemical neuroscience 7 (5), 528-533, 2016
Immediate and Persistent Effects of Salvinorin A on the Kappa Opioid Receptor in Rodents, Monitored In Vivo with PET
MS Placzek, GC Van de Bittner, HY Wey, SE Lukas, JM Hooker
Neuropsychopharmacology 40 (13), 2865, 2015
Strategy for dual-analyte luciferin imaging
GC Van de Bittner, CR Bertozzi, CJ Chang
vivo, 2013
Nasal neuron PET imaging quantifies neuron generation and degeneration
GC Van de Bittner, MM Riley, L Cao, J Ehses, SP Herrick, EL Ricq, ...
The Journal of clinical investigation 127 (2), 681-694, 2017
A Chemical Strategy for the Cell-Based Detection of HDAC Activity
HVK Diyabalanage, GC Van de Bittner, EL Ricq, JM Hooker
ACS chemical biology 9 (6), 1257-1262, 2014
Pretensioner of a seatbelt retractor
S Kim
US Patent App. 10/328,161, 2004
Positron emission tomography assessment of the intranasal delivery route for orexin A
GC Van de Bittner, KC Van de Bittner, HY Wey, W Rowe, ...
ACS chemical neuroscience 9 (2), 358-368, 2018
Fluorescent probes for detection of copper
CJ Chang, GC van de Bittner, T Hirayama, C Jefferson
US Patent 8,865,914, 2014
Compounds and Methods for Detecting Reactive Oxygen Species
CJ Chang, GC van de Bittner, EA Dubikovskaya, CR Bertozzi
US Patent App. 13/642,082, 2013
Imaging agents for neural flux
G Van de Bittner, JM Hooker
US Patent 10,519,160, 2019
Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof
CJ Chang, CR Bertozzi, GC van de Bittner, EA Dubikovskaya
US Patent App. 16/440,348, 2019
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