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Nicholas Lesniak
Nicholas Lesniak
Verified email at umich.edu
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Year
A framework for effective application of machine learning to microbiome-based classification problems
BD Topçuoğlu, NA Lesniak, MT Ruffin IV, J Wiens, PD Schloss
MBio 11 (3), 10.1128/mbio. 00434-20, 2020
1362020
The glucoamylase inhibitor acarbose has a diet-dependent and reversible effect on the murine gut microbiome
NT Baxter, NA Lesniak, H Sinani, PD Schloss, NM Koropatkin
Msphere 4 (1), 10.1128/msphere. 00528-18, 2019
532019
Glutathione-dependent one-electron transfer reactions catalyzed by a B12 trafficking protein
Z Li, C Gherasim, NA Lesniak, R Banerjee
Journal of Biological Chemistry 289 (23), 16487-16497, 2014
382014
Fecal short-chain fatty acids are not predictive of colonic tumor status and cannot be predicted based on bacterial community structure
MA Sze, BD Topçuoğlu, NA Lesniak, MT Ruffin IV, PD Schloss
MBio 10 (4), 10.1128/mbio. 01454-19, 2019
342019
Coordination chemistry controls the thiol oxidase activity of the B12-trafficking protein CblC
Z Li, A Shanmuganathan, M Ruetz, K Yamada, NA Lesniak, B Kräutler, ...
Journal of Biological Chemistry 292 (23), 9733-9744, 2017
222017
The gut bacterial community potentiates Clostridioides difficile infection severity
NA Lesniak, AM Schubert, KJ Flynn, JL Leslie, H Sinani, IL Bergin, ...
MBio 13 (4), e01183-22, 2022
182022
Unusual Aerobic Stabilization of Cob(I)alamin by a B12-Trafficking Protein Allows Chemoenzymatic Synthesis of Organocobalamins
Z Li, NA Lesniak, R Banerjee
Journal of the American Chemical Society 136 (46), 16108-16111, 2014
182014
A framework for effective application of machine learning to microbiome-based classification problems. mBio 11: e00434-20
BD Topçuoglu, NA Lesniak, MT Ruffin, J Wiens, PD Schloss, MJ Blaser
172020
Clearance of Clostridioides difficile colonization is associated with antibiotic-specific bacterial changes
NA Lesniak, AM Schubert, H Sinani, PD Schloss
Msphere 6 (3), 10.1128/msphere. 01238-20, 2021
162021
An osmotic laxative renders mice susceptible to prolonged Clostridioides difficile colonization and hinders clearance
S Tomkovich, A Taylor, J King, J Colovas, L Bishop, K McBride, ...
Msphere 6 (5), 10.1128/msphere. 00629-21, 2021
102021
Ten simple rules to increase computational skills among biologists with Code Clubs
AK Hagan, NA Lesniak, MJ Balunas, L Bishop, WL Close, MD Doherty, ...
PLOS Computational Biology 16 (8), e1008119, 2020
82020
The gut bacterial community potentiates
NA Lesniak, AM Schubert, KJ Flynn, JL Leslie, H Sinani, IL Bergin, ...
Clostridioides difficile, 01183-22, 2022
72022
The proton pump inhibitor omeprazole does not promote Clostridioides difficile colonization in a murine model
S Tomkovich, NA Lesniak, Y Li, L Bishop, MJ Fitzgerald, PD Schloss
Msphere 4 (6), 10.1128/msphere. 00693-19, 2019
72019
The gut bacterial community potentiates Clostridioides difficile infection severity. mBio 13: e0118322
NA Lesniak, AM Schubert, KJ Flynn, JL Leslie, H Sinani, IL Bergin, ...
52022
The proton pump inhibitor omeprazole does not promote Clostridioides difficile colonization in a murine model. mSphere 4: e00693-19
S Tomkovich, NA Lesniak, Y Li, L Bishop, MJ Fitzgerald, PD Schloss
42019
Developing and deploying an integrated workshop curriculum teaching computational skills for reproducible research
Z Lapp, KL Sovacool, N Lesniak, D King, C Barnier, M Flickinger, J Krüger, ...
The Journal of open source education 5 (47), 2022
32022
Diluted fecal community transplant restores Clostridioides difficile colonization resistance to antibiotic-perturbed murine communities
NA Lesniak, S Tomkovich, A Henry, A Taylor, J Colovas, L Bishop, ...
Mbio 13 (4), e01364-22, 2022
22022
Simplified fecal community transplant restores Clostridioides difficile colonization resistance to antibiotic perturbed murine communities
NA Lesniak, S Tomkovich, A Henry, A Taylor, J Colovas, L Bishop, ...
bioRxiv, 2022.05. 11.491589, 2022
2022
The Effect of Gut Microbiota Variation on Clostridioides difficile Infection
N Lesniak
2022
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Articles 1–19