GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases SQ Tsai, Z Zheng, NT Nguyen, M Liebers, VV Topkar, V Thapar, ... Nature biotechnology 33 (2), 187-197, 2015 | 2254 | 2015 |
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing SQ Tsai, N Wyvekens, C Khayter, JA Foden, V Thapar, D Reyon, ... Nature biotechnology 32 (6), 569-576, 2014 | 1265 | 2014 |
Non-cell-autonomous tumor suppression by p53 A Lujambio, L Akkari, J Simon, D Grace, DF Tschaharganeh, JE Bolden, ... Cell 153 (2), 449-460, 2013 | 760 | 2013 |
Stromal microenvironment shapes the intratumoral architecture of pancreatic cancer M Ligorio, S Sil, J Malagon-Lopez, LT Nieman, S Misale, M Di Pilato, ... Cell 178 (1), 160-175. e27, 2019 | 441 | 2019 |
EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma N Riggi, B Knoechel, SM Gillespie, E Rheinbay, G Boulay, ML Suvà, ... Cancer cell 26 (5), 668-681, 2014 | 411 | 2014 |
BRD4 connects enhancer remodeling to senescence immune surveillance N Tasdemir, A Banito, JS Roe, D Alonso-Curbelo, M Camiolo, ... Cancer discovery 6 (6), 612-629, 2016 | 323* | 2016 |
Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles E Reátegui, KE Van Der Vos, CP Lai, M Zeinali, NA Atai, B Aldikacti, ... Nature communications 9 (1), 175, 2018 | 275 | 2018 |
Enhanced isolation and release of circulating tumor cells using nanoparticle binding and ligand exchange in a microfluidic chip MH Park, E Reátegui, W Li, SN Tessier, KHK Wong, AE Jensen, V Thapar, ... Journal of the American Chemical Society 139 (7), 2741-2749, 2017 | 248 | 2017 |
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection N Desai, A Neyaz, A Szabolcs, AR Shih, JH Chen, V Thapar, LT Nieman, ... Nature communications 11 (1), 6319, 2020 | 222 | 2020 |
Minimotif Miner: a tool for investigating protein function S Balla, V Thapar, S Verma, TB Luong, T Faghri, CH Huang, ... Nature methods 3 (3), 175-177, 2006 | 161 | 2006 |
Prediction of potent shRNAs with a sequential classification algorithm R Pelossof, L Fairchild, CH Huang, C Widmer, VT Sreedharan, N Sinha, ... Nature biotechnology 35 (4), 350-353, 2017 | 144 | 2017 |
Development of siRNA Payloads to Target KRAS-Mutant Cancer TL Yuan, C Fellmann, CS Lee, CD Ritchie, V Thapar, LC Lee, DJ Hsu, ... Cancer discovery 4 (10), 1182-1197, 2014 | 122 | 2014 |
Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma RL Porter, NKC Magnus, V Thapar, R Morris, A Szabolcs, A Neyaz, ... Proceedings of the National Academy of Sciences 116 (52), 26835-26845, 2019 | 88 | 2019 |
Parametric studies on bio-diesel prepared from rice bran oil PK Gupta, R Kumar, BS Panesar, VK Thapar Agricultural Engineering International: CIGR Journal, 2007 | 62 | 2007 |
Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells KHK Wong, SN Tessier, DT Miyamoto, KL Miller, LD Bookstaver, ... Nature communications 8 (1), 1733, 2017 | 60 | 2017 |
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs VK Kundeti, S Rajasekaran, H Dinh, M Vaughn, V Thapar BMC bioinformatics 11, 1-14, 2010 | 47 | 2010 |
A tunable delivery platform to provide local chemotherapy for pancreatic ductal adenocarcinoma L Indolfi, M Ligorio, DT Ting, K Xega, AR Tzafriri, F Bersani, N Aceto, ... Biomaterials 93, 71-82, 2016 | 41 | 2016 |
High-performance exact algorithms for motif search S Rajasekaran, S Balla, CH Huang, V Thapar, M Gryk, M Maciejewski, ... Journal of clinical monitoring and computing 19, 319-328, 2005 | 36 | 2005 |
Reverse transcriptase inhibition disrupts repeat element life cycle in colorectal cancer M Rajurkar, AR Parikh, A Solovyov, E You, AS Kulkarni, C Chu, KH Xu, ... Cancer discovery 12 (6), 1462-1481, 2022 | 30 | 2022 |
Storage studies on plant oils and their methyl esters MK Sangha, PK Gupta, SR Verma Agricultural Engineering International: CIGR Journal, 2004 | 23 | 2004 |