Kyle Jeffrie Gaulton
Kyle Jeffrie Gaulton
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The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
A Mahajan, MJ Go, W Zhang, JE Below, KJ Gaulton, T Ferreira, ...
Nature genetics 46 (3), 234-244, 2014
A map of open chromatin in human pancreatic islets
KJ Gaulton, T Nammo, L Pasquali, JM Simon, PG Giresi, MP Fogarty, ...
Nature genetics 42 (3), 255-259, 2010
An expanded genome-wide association study of type 2 diabetes in Europeans
RA Scott, LJ Scott, R Mägi, L Marullo, KJ Gaulton, M Kaakinen, ...
Diabetes 66 (11), 2888-2902, 2017
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
L Pasquali, KJ Gaulton, SA Rodríguez-Seguí, L Mularoni, ...
Nature genetics 46 (2), 136-143, 2014
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
LA Lotta, P Gulati, FR Day, F Payne, H Ongen, M Van De Bunt, ...
Nature genetics 49 (1), 17-26, 2017
Genome-wide associations for birth weight and correlations with adult disease
M Horikoshi, RN Beaumont, FR Day, NM Warrington, MN Kooijman, ...
Nature 538 (7624), 248-252, 2016
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ...
Nature genetics 47 (12), 1415-1425, 2015
Detection of human adaptation during the past 2000 years
Y Field, EA Boyle, N Telis, Z Gao, KJ Gaulton, D Golan, L Yengo, ...
Science 354 (6313), 760-764, 2016
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ...
Nature medicine 27 (3), 546-559, 2021
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
NM Warrington, RN Beaumont, M Horikoshi, FR Day, Ø Helgeland, ...
Nature genetics 51 (5), 804-814, 2019
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol
LA Lange, Y Hu, H Zhang, C Xue, EM Schmidt, ZZ Tang, C Bizon, ...
The American Journal of Human Genetics 94 (2), 233-245, 2014
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: a soft clustering analysis
MS Udler, J Kim, M von Grotthuss, S Bonàs-Guarch, JB Cole, J Chiou, ...
PLoS medicine 15 (9), e1002654, 2018
The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis
M van de Bunt, KJ Gaulton, L Parts, I Moran, PR Johnson, CM Lindgren, ...
PloS one 8 (1), e55272, 2013
Choice of transcripts and software has a large effect on variant annotation
DJ McCarthy, P Humburg, A Kanapin, MA Rivas, K Gaulton, JB Cazier, ...
Genome medicine 6 (3), 1-16, 2014
Transcript expression data from human islets links regulatory signals from genome-wide association studies for type 2 diabetes and glycemic traits to their downstream effectors
M van de Bunt, JE Manning Fox, X Dai, A Barrett, C Grey, L Li, AJ Bennett, ...
PLoS genetics 11 (12), e1005694, 2015
The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease
L Moutsianas, V Agarwala, C Fuchsberger, J Flannick, MA Rivas, ...
PLoS genetics 11 (4), e1005165, 2015
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
AR Majithia, J Flannick, P Shahinian, M Guo, MA Bray, P Fontanillas, ...
Proceedings of the National Academy of Sciences 111 (36), 13127-13132, 2014
Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes
KJ Gaulton, CJ Willer, Y Li, LJ Scott, KN Conneely, AU Jackson, ...
Diabetes 57 (11), 3136-3144, 2008
A computational system to select candidate genes for complex human traits
KJ Gaulton, KL Mohlke, TJ Vision
Bioinformatics 23 (9), 1132-1140, 2007
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