Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes Y Elyahu, I Hekselman, I Eizenberg-Magar, O Berner, I Strominger, ... Science advances 5 (8), eaaw8330, 2019 | 186 | 2019 |
Mechanisms of tissue and cell-type specificity in heritable traits and diseases I Hekselman, E Yeger-Lotem Nature Reviews Genetics 21 (3), 137-150, 2020 | 114 | 2020 |
The TissueNet v. 2 database: a quantitative view of protein-protein interactions across human tissues O Basha, R Barshir, M Sharon, E Lerman, BF Kirson, I Hekselman, ... Nucleic acids research 45 (D1), D427-D431, 2017 | 70 | 2017 |
The landscape of molecular chaperones across human tissues reveals a layered architecture of core and variable chaperones N Shemesh, J Jubran, S Dror, E Simonovsky, O Basha, C Argov, ... Nature communications 12 (1), 2180, 2021 | 66 | 2021 |
Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease A Cain, M Taga, C McCabe, GS Green, I Hekselman, CC White, DI Lee, ... Nature neuroscience 26 (7), 1267-1280, 2023 | 53 | 2023 |
Role of duplicate genes in determining the tissue-selectivity of hereditary diseases R Barshir, I Hekselman, N Shemesh, M Sharon, L Novack, E Yeger-Lotem PLoS genetics 14 (5), e1007327, 2018 | 36 | 2018 |
Differential network analysis of multiple human tissue interactomes highlights tissue-selective processes and genetic disorder genes O Basha, CM Argov, R Artzy, Y Zoabi, I Hekselman, L Alfandari, ... Bioinformatics 36 (9), 2821-2828, 2020 | 28 | 2020 |
Fractional exhaled Nitric Oxide (FeNO) level as a predictor of COVID-19 disease severity Y Lior, N Yatzkan, I Brami, Y Yogev, R Riff, I Hekselman, M Fremder, ... Nitric Oxide 124, 68-73, 2022 | 14 | 2022 |
The differential activity of biological processes in tissues and cell subsets can illuminate disease-related processes and cell-type identities M Sharon, E Vinogradov, CM Argov, O Lazarescu, Y Zoabi, I Hekselman, ... Bioinformatics 38 (6), 1584-1592, 2022 | 9 | 2022 |
Dosage-sensitive molecular mechanisms are associated with the tissue-specificity of traits and diseases J Jubran, I Hekselman, L Novack, E Yeger-Lotem Computational and Structural Biotechnology Journal 18, 4024-4032, 2020 | 7 | 2020 |
The organ-disease annotations (ODiseA) database of hereditary diseases and inflicted tissues I Hekselman, L Kerber, M Ziv, G Gruber, E Yeger-Lotem Journal of Molecular Biology 434 (11), 167619, 2022 | 5 | 2022 |
Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes. Sci Adv 5: eaaw8330 Y Elyahu, I Hekselman, I Eizenberg-Magar | 5 | 2019 |
Predicting molecular mechanisms of hereditary diseases by using their tissue‐selective manifestation E Simonovsky, M Sharon, M Ziv, O Mauer, I Hekselman, J Jubran, ... Molecular Systems Biology 19 (8), e11407, 2023 | 4 | 2023 |
A tissue-aware machine learning framework enhances the mechanistic understanding and genetic diagnosis of Mendelian and rare diseases E Simonovsky, M Sharon, M Ziv, O Mauer, I Hekselman, J Jubran, ... bioRxiv, 2021.02. 16.430825, 2021 | 2 | 2021 |
Differential network analysis of human tissue interactomes highlights tissue-selective processes and genetic disorder genes O Basha, CM Argov, R Artzy, Y Zoabi, I Hekselman, L Alfandari, ... bioRxiv, 612143, 2019 | 2 | 2019 |
Affected cell types for hundreds of Mendelian diseases revealed by analysis of human and mouse single-cell data I Hekselman, A Vital, M Ziv-Agam, L Kerber, I Yairi, E Yeger-Lotem Elife 13, e84613, 2024 | 1 | 2024 |
Cost containment by peer prior authorization program for second line treatment in patients with retinal disease A Rosenblatt, I Hekselman, I Rosenblatt, I Hekselman, D Gaton Israel Journal of Health Policy Research 10, 1-10, 2021 | 1 | 2021 |
Human subcutaneous and visceral adipocyte atlases uncover classical and specialized adipocytes and depot-specific patterns O Lazarescu, M Ziv Agam, Y Haim, I Hekselman, J Jubran, A Shneyour, ... bioRxiv, 2023.09. 04.555678, 2023 | | 2023 |
Kits, compositions and methods for evaluating immune system status A Monsonego, E Yeger-Lotem, Y Elyahu, I Hekselman US Patent App. 17/430,304, 2022 | | 2022 |
11 Elucidating Genotype-to-Phenotype Relationships via Analyses of Human Tissue Interactomes I Hekselman, M Sharon, O Basha, E Yeger-Lotem Analyzing Network Data in Biology and Medicine: An Interdisciplinary …, 2019 | | 2019 |