Doc toxin is a kinase that inactivates elongation factor Tu JW Cruz, FP Rothenbacher, T Maehigashi, WS Lane, CM Dunham, ... Journal of Biological Chemistry 289 (11), 7788-7798, 2014 | 99 | 2014 |
Structure of the Proteus vulgaris HigB-(HigA) 2-HigB toxin-antitoxin complex MA Schureck, T Maehigashi, SJ Miles, J Marquez, SE Cho, R Erdman, ... Journal of Biological Chemistry 289 (2), 1060-1070, 2014 | 89 | 2014 |
Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase JW Cruz, JD Sharp, ED Hoffer, T Maehigashi, IO Vvedenskaya, ... Nature communications 6 (1), 7480, 2015 | 88 | 2015 |
Structural insights into+ 1 frameshifting promoted by expanded or modification-deficient anticodon stem loops T Maehigashi, JA Dunkle, SJ Miles, CM Dunham Proceedings of the National Academy of Sciences 111 (35), 12740-12745, 2014 | 68 | 2014 |
High-resolution structure of an extended A-tract:[d (CGCAAATTTGCG)] 2 KK Woods, T Maehigashi, SB Howerton, CC Sines, S Tannenbaum, ... Journal of the American Chemical Society 126 (47), 15330-15331, 2004 | 63 | 2004 |
Structure of the basal components of a bacterial transporter J Meisner, T Maehigashi, I André, CM Dunham, CP Moran Jr Proceedings of the National Academy of Sciences 109 (14), 5446-5451, 2012 | 60 | 2012 |
B-DNA structure is intrinsically polymorphic: even at the level of base pair positions T Maehigashi, C Hsiao, K Kruger Woods, T Moulaei, NV Hud, ... Nucleic acids research 40 (8), 3714-3722, 2012 | 52 | 2012 |
Mechanisms of toxin inhibition and transcriptional repression by Escherichia coli DinJ-YafQ A Ruangprasert, T Maehigashi, SJ Miles, N Giridharan, JX Liu, ... Journal of Biological Chemistry 289 (30), 20559-20569, 2014 | 51 | 2014 |
Mechanism of tRNA-mediated+ 1 ribosomal frameshifting S Hong, S Sunita, T Maehigashi, ED Hoffer, JA Dunkle, CM Dunham Proceedings of the National Academy of Sciences 115 (44), 11226-11231, 2018 | 43 | 2018 |
Defining the mRNA recognition signature of a bacterial toxin protein MA Schureck, JA Dunkle, T Maehigashi, SJ Miles, CM Dunham Proceedings of the National Academy of Sciences 112 (45), 13862-13867, 2015 | 36 | 2015 |
Molecular basis of ribosome recognition and mRNA hydrolysis by the E. coli YafQ toxin T Maehigashi, A Ruangprasert, SJ Miles, CM Dunham Nucleic acids research 43 (16), 8002-8012, 2015 | 34 | 2015 |
Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state CE Fagan, JA Dunkle, T Maehigashi, MN Dang, A Devaraj, SJ Miles, ... Proceedings of the National Academy of Sciences 110 (24), 9716-9721, 2013 | 34 | 2013 |
Structure of B-DNA with Cations Tethered in the Major Groove, T Moulaei, T Maehigashi, GT Lountos, S Komeda, D Watkins, MP Stone, ... Biochemistry 44 (20), 7458-7468, 2005 | 33 | 2005 |
Structural insights into translational recoding by frameshift suppressor tRNASufJ CE Fagan, T Maehigashi, JA Dunkle, SJ Miles, CM Dunham RNA 20 (12), 1944-1954, 2014 | 28 | 2014 |
Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon–anticodon pairing ED Hoffer, S Hong, S Sunita, T Maehigashi, RL Gonzalez, PC Whitford, ... Elife 9, e51898, 2020 | 27 | 2020 |
Comparative study of the temperature sensitive, cold adapted and attenuated mutations present in the master donor viruses of the two commercial human live attenuated influenza … L Rodriguez, P Blanco-Lobo, EC Reilly, T Maehigashi, A Nogales, ... Viruses 11 (10), 928, 2019 | 23 | 2019 |
Interplay of ancestral non-primate lentiviruses with the virus-restricting SAMHD1 proteins of their hosts SA Mereby, T Maehigashi, JM Holler, DH Kim, RF Schinazi, B Kim Journal of Biological Chemistry 293 (42), 16402-16412, 2018 | 20 | 2018 |
A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site T Maehigashi, S Ahn, UI Kim, J Lindenberger, A Oo, PC Koneru, ... PLoS pathogens 17 (7), e1009671, 2021 | 17 | 2021 |
Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability IJ Pavelich, T Maehigashi, ED Hoffer, A Ruangprasert, SJ Miles, ... Nucleic acids research 47 (19), 10400-10413, 2019 | 14 | 2019 |
Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding ED Hoffer, T Maehigashi, K Fredrick, CM Dunham Nucleic Acids Research 47 (3), 1557-1563, 2019 | 14 | 2019 |