Clarence Yapp
Clarence Yapp
Harvard Medical School, University of Oxford
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Cited by
Cited by
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
JR Lin, B Izar, S Wang, C Yapp, S Mei, PM Shah, S Santagata, PK Sorger
elife 7, e31657, 2018
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues
SK Saka, Y Wang, JY Kishi, A Zhu, Y Zeng, W Xie, K Kirli, C Yapp, ...
Nature biotechnology 37 (9), 1080-1090, 2019
Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains
DA Hay, O Fedorov, S Martin, DC Singleton, C Tallant, C Wells, S Picaud, ...
Journal of the American Chemical Society 136 (26), 9308-9319, 2014
Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy
S Picaud, O Fedorov, A Thanasopoulou, K Leonards, K Jones, J Meier, ...
Cancer research 75 (23), 5106-5119, 2015
Inflammation activation and resolution in human tendon disease
SG Dakin, FO Martinez, C Yapp, G Wells, U Oppermann, BJF Dean, ...
Science translational medicine 7 (311), 311ra173-311ra173, 2015
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
A Färkkilä, DC Gulhan, J Casado, CA Jacobson, H Nguyen, ...
Nature communications 11 (1), 1459, 2020
5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ...
Chemical science 4 (8), 3110-3117, 2013
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides
A Kawamura, M Münzel, T Kojima, C Yapp, B Bhushan, Y Goto, A Tumber, ...
Nature communications 8 (1), 14773, 2017
MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging
D Schapiro, A Sokolov, C Yapp, YA Chen, JL Muhlich, J Hess, ...
Nature methods 19 (3), 311-315, 2022
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities
D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ...
Journal of medicinal chemistry 57 (1), 42-55, 2014
Potent and selective KDM5 inhibitor stops cellular demethylation of H3K4me3 at transcription start sites and proliferation of MM1S myeloma cells
A Tumber, A Nuzzi, ES Hookway, SB Hatch, S Velupillai, C Johansson, ...
Cell chemical biology 24 (3), 371-380, 2017
Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer
JR Lin, S Wang, S Coy, YA Chen, C Yapp, M Tyler, MK Nariya, CN Heiser, ...
Cell 186 (2), 363-381. e19, 2023
The spatial landscape of progression and immunoediting in primary melanoma at single-cell resolution
AJ Nirmal, Z Maliga, T Vallius, B Quattrochi, AA Chen, CA Jacobson, ...
Cancer Discovery 12 (6), 1518-1541, 2022
[1,2,4]Triazolo[4,3-a]phthalazines: Inhibitors of Diverse Bromodomains
O Fedorov, H Lingard, C Wells, OP Monteiro, S Picaud, T Keates, C Yapp, ...
Journal of medicinal chemistry 57 (2), 462-476, 2014
Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies
D Reichart, EL Lindberg, H Maatz, AMA Miranda, A Viveiros, N Shvetsov, ...
Science 377 (6606), eabo1984, 2022
Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching
M Philpott, CM Rogers, C Yapp, C Wells, JP Lambert, C Strain-Damerell, ...
Epigenetics & chromatin 7, 1-12, 2014
HSF1 phase transition mediates stress adaptation and cell fate decisions
G Gaglia, R Rashid, C Yapp, GN Joshi, CG Li, SL Lindquist, KA Sarosiek, ...
Nature Cell Biology 22 (2), 151-158, 2020
Stitching and registering highly multiplexed whole-slide images of tissues and tumors using ASHLAR
JL Muhlich, YA Chen, C Yapp, D Russell, S Santagata, PK Sorger
Bioinformatics 38 (19), 4613-4621, 2022
Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting …
CL Sutherell, C Tallant, OP Monteiro, C Yapp, JE Fuchs, O Fedorov, ...
Journal of Medicinal Chemistry 59 (10), 5095-5101, 2016
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