Nesli Ece Sen
Nesli Ece Sen
Max Planck Institute for Brain Research, Goethe University Frankfurt Medical School
Verified email at
Cited by
Cited by
The distinct genetic pattern of ALS in Turkey and novel mutations
A Özoğuz, Ö Uyan, G Birdal, C Iskender, E Kartal, S Lahut, Ö Ömür, ...
Neurobiology of aging 36 (4), 1764. e9-1764. e18, 2015
Ataxin-2 (Atxn2)-knock-out mice show branched chain amino acids and fatty acids pathway alterations
D Meierhofer, M Halbach, NE Şen, S Gispert, G Auburger
Molecular & Cellular Proteomics 15 (5), 1728-1739, 2016
Efficient prevention of neurodegenerative diseases by depletion of starvation response factor Ataxin-2
G Auburger, NE Sen, D Meierhofer, AN Başak, AD Gitler
Trends in neurosciences 40 (8), 507-516, 2017
Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels
NE Sen, J Drost, S Gispert, S Torres-Odio, E Damrath, M Klinkenberg, ...
Neurobiology of disease 96, 115-126, 2016
Quantitative global proteomics of yeast PBP1 deletion mutants and their stress responses identifies glucose metabolism, mitochondrial, and stress granule changes
G Seidel, D Meierhofer, NE Şen, A Guenther, S Krobitsch, G Auburger
Journal of proteome research 16 (2), 504-515, 2017
Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated
MV Halbach, T Stehning, E Damrath, M Jendrach, NE Şen, AN Başak, ...
PLoS One 10 (3), e0121089, 2015
Elevated global DNA methylation is not exclusive to amyotrophic lateral sclerosis and is also observed in spinocerebellar ataxia types 1 and 2
H Hamzeiy, D Savaş, C Tunca, NE Şen, AG Eken, I Şahbaz, D Calini, ...
Neurodegenerative Diseases 18 (1), 38-48, 2018
In human and mouse Spino-cerebellar tissue, Ataxin-2 expansion affects Ceramide-Sphingomyelin metabolism
NE Sen, A Arsovic, D Meierhofer, S Brodesser, C Oberschmidt, ...
International journal of molecular sciences 20 (23), 5854, 2019
Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation
NE Sen, J Canet-Pons, MV Halbach, A Arsovic, U Pilatus, WH Chae, ...
Neurobiology of disease 132, 104559, 2019
PINK1 and Ataxin-2 as modifiers of growth
NE Sen, S Gispert, G Auburger
Oncotarget 8 (20), 32382, 2017
Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression
J Canet-Pons, NE Sen, A Arsovic, LE Almaguer-Mederos, MV Halbach, ...
Neurobiology of Disease, 105289, 2021
Mid-Gestation lethality of Atxn2l-Ablated Mice
J Key, PN Harter, NE Sen, E Gradhand, G Auburger, S Gispert
International journal of molecular sciences 21 (14), 5124, 2020
SerThr-PhosphoProteome of brain from aged PINK1-KO+ A53T-SNCA mice reveals pT1928-MAP1B and pS3781-ANK2 deficits, as hub between autophagy and synapse changes
G Auburger, S Gispert, S Torres-Odio, M Jendrach, N Brehm, ...
International journal of molecular sciences 20 (13), 3284, 2019
Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence
J Key, NE Sen, A Arsović, S Krämer, R Hülse, NN Khan, D Meierhofer, ...
Cells 9 (10), 2229, 2020
Revisiting the complex architecture of ALS in Turkey: Expanding genotypes, shared phenotypes, molecular networks, and a public variant database
C Tunca, T Şeker, F Akçimen, C Coşkun, E Bayraktar, R Palvadeau, S Zor, ...
Human Mutation 41 (8), e7-e45, 2020
In spino-cerebellar tissue, Ataxin-2 expansion affects ceramide-sphingomyelin metabolism
NE Sen, A Arsovic, D Meierhofer, S Brodesser, C Oberschmidt, ...
Preprints, 2019
Cover, Volume 41, Issue 8
C Tunca, T Şeker, F Akçimen, C Coşkun, E Bayraktar, R Palvadeau, S Zor, ...
Human Mutation 41 (8), iv-iv, 2020
Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule—Purkinje Neuron Synaptic Strength
A Arsović, MV Halbach, J Canet-Pons, D Esen-Sehir, C Döring, ...
International journal of molecular sciences 21 (18), 6673, 2020
Ataxin-2 Binds Alpha-Actinin-1
F Eich, DF Nonis, NE Sen, J Nowock, G Auburger
Preprints, 2019
Iron Depletion Reduces Abce1 Transcripts While Inducing the Mitophagy Factors Pink1 and Parkin
J Key, NE Sen, A Arsovic, S Krämer, R Hülse, S Gispert-Sanchez, ...
Preprints, 2019
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