Nesli Ece Sen
Nesli Ece Sen
Max Planck Institute for Brain Research, Goethe University Frankfurt Medical School
Verified email at stud.uni-frankfurt.de
Title
Cited by
Cited by
Year
The distinct genetic pattern of ALS in Turkey and novel mutations
A Özoğuz, Ö Uyan, G Birdal, C Iskender, E Kartal, S Lahut, Ö Ömür, ...
Neurobiology of aging 36 (4), 1764. e9-1764. e18, 2015
792015
Ataxin-2 (Atxn2)-knock-out mice show branched chain amino acids and fatty acids pathway alterations
D Meierhofer, M Halbach, NE Şen, S Gispert, G Auburger
Molecular & Cellular Proteomics 15 (5), 1728-1739, 2016
542016
Efficient prevention of neurodegenerative diseases by depletion of starvation response factor Ataxin-2
G Auburger, NE Sen, D Meierhofer, AN Başak, AD Gitler
Trends in neurosciences 40 (8), 507-516, 2017
382017
Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels
NE Sen, J Drost, S Gispert, S Torres-Odio, E Damrath, M Klinkenberg, ...
Neurobiology of disease 96, 115-126, 2016
282016
Quantitative global proteomics of yeast PBP1 deletion mutants and their stress responses identifies glucose metabolism, mitochondrial, and stress granule changes
G Seidel, D Meierhofer, NE Şen, A Guenther, S Krobitsch, G Auburger
Journal of proteome research 16 (2), 504-515, 2017
202017
Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated
MV Halbach, T Stehning, E Damrath, M Jendrach, NE Şen, AN Başak, ...
PLoS One 10 (3), e0121089, 2015
182015
Elevated global DNA methylation is not exclusive to amyotrophic lateral sclerosis and is also observed in spinocerebellar ataxia types 1 and 2
H Hamzeiy, D Savaş, C Tunca, NE Şen, AG Eken, I Şahbaz, D Calini, ...
Neurodegenerative Diseases 18 (1), 38-48, 2018
162018
In human and mouse Spino-cerebellar tissue, Ataxin-2 expansion affects Ceramide-Sphingomyelin metabolism
NE Sen, A Arsovic, D Meierhofer, S Brodesser, C Oberschmidt, ...
International journal of molecular sciences 20 (23), 5854, 2019
142019
Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation
NE Sen, J Canet-Pons, MV Halbach, A Arsovic, U Pilatus, WH Chae, ...
Neurobiology of disease 132, 104559, 2019
132019
PINK1 and Ataxin-2 as modifiers of growth
NE Sen, S Gispert, G Auburger
Oncotarget 8 (20), 32382, 2017
62017
Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression
J Canet-Pons, NE Sen, A Arsovic, LE Almaguer-Mederos, MV Halbach, ...
Neurobiology of Disease, 105289, 2021
32021
Mid-Gestation lethality of Atxn2l-Ablated Mice
J Key, PN Harter, NE Sen, E Gradhand, G Auburger, S Gispert
International journal of molecular sciences 21 (14), 5124, 2020
32020
SerThr-PhosphoProteome of brain from aged PINK1-KO+ A53T-SNCA mice reveals pT1928-MAP1B and pS3781-ANK2 deficits, as hub between autophagy and synapse changes
G Auburger, S Gispert, S Torres-Odio, M Jendrach, N Brehm, ...
International journal of molecular sciences 20 (13), 3284, 2019
32019
Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence
J Key, NE Sen, A Arsović, S Krämer, R Hülse, NN Khan, D Meierhofer, ...
Cells 9 (10), 2229, 2020
12020
Revisiting the complex architecture of ALS in Turkey: Expanding genotypes, shared phenotypes, molecular networks, and a public variant database
C Tunca, T Şeker, F Akçimen, C Coşkun, E Bayraktar, R Palvadeau, S Zor, ...
Human Mutation 41 (8), e7-e45, 2020
12020
In spino-cerebellar tissue, Ataxin-2 expansion affects ceramide-sphingomyelin metabolism
NE Sen, A Arsovic, D Meierhofer, S Brodesser, C Oberschmidt, ...
Preprints, 2019
12019
Cover, Volume 41, Issue 8
C Tunca, T Şeker, F Akçimen, C Coşkun, E Bayraktar, R Palvadeau, S Zor, ...
Human Mutation 41 (8), iv-iv, 2020
2020
Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule—Purkinje Neuron Synaptic Strength
A Arsović, MV Halbach, J Canet-Pons, D Esen-Sehir, C Döring, ...
International journal of molecular sciences 21 (18), 6673, 2020
2020
Ataxin-2 Binds Alpha-Actinin-1
F Eich, DF Nonis, NE Sen, J Nowock, G Auburger
Preprints, 2019
2019
Iron Depletion Reduces Abce1 Transcripts While Inducing the Mitophagy Factors Pink1 and Parkin
J Key, NE Sen, A Arsovic, S Krämer, R Hülse, S Gispert-Sanchez, ...
Preprints, 2019
2019
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